Combining fatty acid amide hydrolase (FAAH) inhibition with peroxisome proliferator-activated receptor (PPAR) activation: a new potential multi-target therapeutic strategy for the...

by Leonardo Brunetti, Antonio Laghezza, Fulvio Loiodice, Paolo Tortorella, Luca Piemontese
Published 2020-01-01

Importance of Biometals as Targets in Medicinal Chemistry: An Overview about the Role of Zinc (II) Chelating Agents

by Rosalba Leuci, Leonardo Brunetti, Antonio Laghezza, Fulvio Loiodice, Paolo Tortorella, Luca Piemontese
Published 2020-06-01

Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors

by Leonardo Brunetti, Antonio Carrieri, Luca Piemontese, Paolo Tortorella, Fulvio Loiodice, Antonio Laghezza
Published 2020-09-01

(2-Aminobenzothiazole)-Methyl-1,1-Bisphosphonic Acids: Targeting Matrix Metalloproteinase 13 Inhibition to the Bone

by Antonio Laghezza, Luca Piemontese, Leonardo Brunetti, Alessia Caradonna, Mariangela Agamennone, Fulvio Loiodice, Paolo Tortorella
Published 2021-01-01

Natural Compounds for the Prevention and Treatment of Cardiovascular and Neurodegenerative Diseases

by Rosalba Leuci, Leonardo Brunetti, Viviana Poliseno, Antonio Laghezza, Fulvio Loiodice, Paolo Tortorella, Luca Piemontese
Published 2021-12-01

H-NMR determination of the enantiomeric excess of the antiarrhytmic drug Mexiletine by using mandelic acid analogues as chiral solvating agents

by Giuseppe Carbonara, Alessia Carocci, Giuseppe Fracchiolla, Carlo Franchini, Giovanni Lentini, Fulvio Loiodice, Paolo Tortorella
Published 2003-10-01

Dual targeting of cancer-related human matrix metalloproteinases and carbonic anhydrases by chiral N-(biarylsulfonyl)-phosphonic acids

by Grazia Luisi, Guido Angelini, Carla Gasbarri, Antonio Laghezza, Mariangela Agamennone, Fulvio Loiodice, Claudiu T. Supuran, Cristina Campestre, Paolo Tortorella
Published 2017-01-01

Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease

by Luca Piemontese, Gabriele Vitucci, Marco Catto, Antonio Laghezza, Filippo Maria Perna, Mariagrazia Rullo, Fulvio Loiodice, Vito Capriati, Michele Solfrizzo
Published 2018-08-01

Antiproliferative Activity Evaluation of a Series of N-1,3-Benzothiazol-2-ylbenzamides as Novel Apoptosis Inducers

by Filomena Corbo, Alessia Carocci, Domenico Armenise, Nicolino De Laurentis, Antonio Laghezza, Fulvio Loiodice, Patrizia Ancona, Marilena Muraglia, Vincenzo Pagliarulo, Carlo Franchini, Alessia Catalano
Published 2016-01-01

Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis

by Gloria Brusotti, Roberta Montanari, Davide Capelli, Giulia Cattaneo, Antonio Laghezza, Paolo Tortorella, Fulvio Loiodice, Franck Peiretti, Bernadette Bonardo, Alessandro Paiardini, Enrica Calleri, Giorgio Pochetti
Published 2017-07-01

Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer’s Disease Agents

by Viviana Poliseno, Sílvia Chaves, Leonardo Brunetti, Fulvio Loiodice, Antonio Carrieri, Antonio Laghezza, Paolo Tortorella, João D. Magalhães, Sandra M. Cardoso, M. Amélia Santos, Luca Piemontese
Published 2021-01-01

Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal Malignancy

by Antonio Laghezza, Luca Piemontese, Leonardo Brunetti, Alessia Caradonna, Mariangela Agamennone, Antonella Di Pizio, Giorgio Pochetti, Roberta Montanari, Davide Capelli, Marilena Tauro, Fulvio Loiodice, Paolo Tortorella
Published 2020-06-01