Dual-site phosphorylation of the control of virulence regulator impacts group a streptococcal global gene expression and pathogenesis.

by Nicola Horstmann, Miguel Saldaña, Pranoti Sahasrabhojane, Hui Yao, Xiaoping Su, Erika Thompson, Antonius Koller, Samuel A Shelburne
Published 2014-05-01

A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection.

by Samuel A Shelburne, Randall J Olsen, Bryce Suber, Pranoti Sahasrabhojane, Paul Sumby, Richard G Brennan, James M Musser
Published 2010-03-01

Streptococcus mitis Strains Causing Severe Clinical Disease in Cancer Patients

by Samuel A. Shelburne, Pranoti Sahasrabhojane, Miguel Saldana, Hui Yao, Xiaoping Su, Nicola Horstmann, Erika Thompson, Anthony R. Flores
Published 2014-05-01

VAMPr: VAriant Mapping and Prediction of antibiotic resistance via explainable features and machine learning.

by Jiwoong Kim, David E Greenberg, Reed Pifer, Shuang Jiang, Guanghua Xiao, Samuel A Shelburne, Andrew Koh, Yang Xie, Xiaowei Zhan
Published 2020-01-01

Observational Cohort Study of Oral Mycobiome and Interkingdom Interactions over the Course of Induction Therapy for Leukemia

by Sarah Robinson, Christine B. Peterson, Pranoti Sahasrabhojane, Nadim J. Ajami, Samuel A. Shelburne, Dimitrios P. Kontoyiannis, Jessica R. Galloway-Peña
Published 2020-04-01

Phosphatase activity of the control of virulence sensor kinase CovS is critical for the pathogenesis of group A streptococcus.

by Nicola Horstmann, Chau Nguyen Tran, Chelcy Brumlow, Sruti DebRoy, Hui Yao, Graciela Nogueras Gonzalez, Nishanth Makthal, Muthiah Kumaraswami, Samuel A Shelburne
Published 2018-10-01

Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis.

by Nicola Horstmann, Pranoti Sahasrabhojane, Bryce Suber, Muthiah Kumaraswami, Randall J Olsen, Anthony Flores, James M Musser, Richard G Brennan, Samuel A Shelburne
Published 2011-10-01

Population Genomics of <italic toggle="yes">emm4</italic> Group A <named-content content-type="genus-species">Streptococcus</named-content> Reveals Progressive Replacement with a H...

by Sruti DebRoy, Misu Sanson, Brittany Shah, Shirjana Regmi, Luis Alberto Vega, Chioma Odo, Pranoti Sahasrabhojane, Allison McGeer, Gregory J. Tyrrell, Nahuel Fittipaldi, Samuel A. Shelburne, Anthony R. Flores
Published 2021-08-01

Identifying novel genes and biological processes relevant to the development of cancer therapy-induced mucositis: An informative gene network analysis.

by Cielito C Reyes-Gibby, Stephanie C Melkonian, Jian Wang, Robert K Yu, Samuel A Shelburne, Charles Lu, Gary Brandon Gunn, Mark S Chambers, Ehab Y Hanna, Sai-Ching J Yeung, Sanjay Shete
Published 2017-01-01

Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface.

by Jessica Galloway-Peña, Sruti DebRoy, Chelcy Brumlow, Xiqi Li, Truc T Tran, Nicola Horstmann, Hui Yao, Ken Chen, Fang Wang, Bih-Fang Pan, David H Hawke, Erika J Thompson, Cesar A Arias, Vance G Fowler, Micah M Bhatti, Awdhesh Kalia, Anthony R Flores, Samuel A Shelburne
Published 2018-01-01

Implementation of a Pan-Genomic Approach to Investigate Holobiont-Infecting Microbe Interaction: A Case Report of a Leukemic Patient with Invasive Mucormycosis.

by Samuel A Shelburne, Nadim J Ajami, Marcus C Chibucos, Hannah C Beird, Jeffrey Tarrand, Jessica Galloway-Peña, Nathan Albert, Roy F Chemaly, Shashank S Ghantoji, Lisa Marsh, Naveen Pemmaraju, Michael Andreeff, Elizabeth J Shpall, Jennifer A Wargo, Katayoun Rezvani, Amin Alousi, Vincent M Bruno, Phillip A Futreal, Joseph F Petrosino, Dimitrios P Kontoyiannis
Published 2015-01-01