Selective Targeting of TNF Receptors as a Novel Therapeutic Approach

by Roman Fischer, Roland E. Kontermann, Klaus Pfizenmaier
Published 2020-05-01

Targeting sTNF/TNFR1 Signaling as a New Therapeutic Strategy

by Roman Fischer, Roland E. Kontermann, Olaf Maier
Published 2015-03-01

A Fab-Selective Immunoglobulin-Binding Domain from Streptococcal Protein G with Improved Half-Life Extension Properties.

by Felix Unverdorben, Meike Hutt, Oliver Seifert, Roland E Kontermann
Published 2015-01-01

A scDb-based trivalent bispecific antibody for T-cell-mediated killing of HER3-expressing cancer cells

by Nadine Aschmoneit, Sophia Steinlein, Lennart Kühl, Oliver Seifert, Roland E. Kontermann
Published 2021-07-01

Antitumor Activity of a Mesenchymal Stem Cell Line Stably Secreting a Tumor-Targeted TNF-Related Apoptosis-Inducing Ligand Fusion Protein

by Irene Marini, Martin Siegemund, Meike Hutt, Roland E. Kontermann, Klaus Pfizenmaier
Published 2017-05-01

Dual Targeting of Tumor Cells with Bispecific Single-Chain Fv-Immunoliposomes

by Katharina Mack, Ronny Rüger, Sina Fellermeier, Oliver Seifert, Roland E. Kontermann
Published 2012-07-01

Superior Treg-Expanding Properties of a Novel Dual-Acting Cytokine Fusion Protein

by Tanja Padutsch, Maksim Sendetski, Carina Huber, Nathalie Peters, Klaus Pfizenmaier, Klaus Pfizenmaier, John R. Bethea, Roland E. Kontermann, Roland E. Kontermann, Roman Fischer, Roman Fischer
Published 2019-12-01

Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans

by Sina Fellermeier-Kopf, Friederike Gieseke, Ugur Sahin, Dafne Müller, Klaus Pfizenmaier, Roland E. Kontermann
Published 2018-09-01

Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity.

by Fabian Richter, Timo Liebig, Eric Guenzi, Andreas Herrmann, Peter Scheurich, Klaus Pfizenmaier, Roland E Kontermann
Published 2013-01-01

Dataset on FAP-induced emergence of spontaneous metastases and on the preparation of activatable FAP-targeting immunoliposomes to detect the metastases

by Felista L. Tansi, Ronny Rüger, Claudia Böhm, Roland E. Kontermann, Ulf K. Teichgraeber, Alfred Fahr, Ingrid Hilger
Published 2016-12-01

Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2

by Roman Fischer, Jessica Marsal, Cristiano Guttà, Stephan A. Eisler, Nathalie Peters, John R. Bethea, Klaus Pfizenmaier, Roland E. Kontermann
Published 2017-07-01

Back-to-Germline (B2G) Procedure for Antibody Devolution

by Anja Schrade, Alexander Bujotzek, Christian Spick, Martina Wagner, Johannes Goerl, Xenia Wezler, Guy Georges, Roland E. Kontermann, Ulrich Brinkmann
Published 2019-08-01

Targeting the Tumor Microenvironment with Fluorescence-Activatable Bispecific Endoglin/Fibroblast Activation Protein Targeting Liposomes

by Felista L. Tansi, Ronny Rüger, Ansgar M. Kollmeier, Markus Rabenhold, Frank Steiniger, Roland E. Kontermann, Ulf K. Teichgräber, Alfred Fahr, Ingrid Hilger
Published 2020-04-01

Dataset on the role of endoglin expression on melanin production in murine melanoma and on the influence of melanin on optical imaging

by Felista L. Tansi, Ronny Rüger, Ansgar M. Kollmeier, Markus Rabenhold, Frank Steiniger, Roland E. Kontermann, Ulf K. Teichgraeber, Alfred Fahr, Ingrid Hilger
Published 2018-10-01

Rapid Target Binding and Cargo Release of Activatable Liposomes Bearing HER2 and FAP Single-Chain Antibody Fragments Reveal Potentials for Image-Guided Delivery to Tumors

by Felista L. Tansi, Ronny Rüger, Claudia Böhm, Frank Steiniger, Martin Raasch, Alexander S. Mosig, Roland E. Kontermann, Ulf K. Teichgräber, Alfred Fahr, Ingrid Hilger
Published 2020-10-01

Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects agains...

by Irini Papazian, Eleni Tsoukala, Athena Boutou, Maria Karamita, Konstantinos Kambas, Lida Iliopoulou, Roman Fischer, Roland E. Kontermann, Maria C. Denis, George Kollias, Hans Lassmann, Lesley Probert
Published 2021-09-01

The TNFR1 Antagonist Atrosimab Is Therapeutic in Mouse Models of Acute and Chronic Inflammation

by Fabian Richter, Fabian Richter, Sarah K. Williams, Sarah K. Williams, Katharina John, Carina Huber, Camille Vaslin, Henri Zanker, Henri Zanker, Richard Fairless, Richard Fairless, Kira Pichi, Kira Pichi, Silke Marhenke, Arndt Vogel, Marie-Ann Dhaen, Stefanie Herrmann, Andreas Herrmann, Klaus Pfizenmaier, Klaus Pfizenmaier, Heike Bantel, Ricarda Diem, Ricarda Diem, Roland E. Kontermann, Roland E. Kontermann, Roman Fischer, Roman Fischer
Published 2021-07-01

Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization.

by Patrick Baum, Ramona Schmid, Carina Ittrich, Werner Rust, Katrin Fundel-Clemens, Susanne Siewert, Martin Baur, Lisa Mara, Lore Gruenbaum, Armin Heckel, Roland Eils, Roland E Kontermann, Gerald J Roth, Florian Gantner, Andreas Schnapp, John E Park, Andreas Weith, Karsten Quast, Detlev Mennerich
Published 2010-12-01