Development of a novel severe triple allergen asthma model in mice which is resistant to dexamethasone and partially resistant to TLR7 and TLR9 agonist treatment.

by Matthias J Duechs, Cornelia Tilp, Christopher Tomsic, Florian Gantner, Klaus J Erb
Published 2014-01-01

Opposing effects of in vitro differentiated macrophages sub-type on epithelial wound healing.

by Julia A Gindele, Samuel Mang, Nicolas Pairet, Ingrid Christ, Florian Gantner, Jürgen Schymeinsky, David J Lamb
Published 2017-01-01

The absence of mrp4 has no effect on the recruitment of neutrophils and eosinophils into the lung after LPS, cigarette smoke or allergen challenge.

by Jürgen Schymeinsky, Hannah Mayer, Christopher Tomsic, Cornelia Tilp, John D Schuetz, Yunhai Cui, Lutz Wollin, Florian Gantner, Klaus J Erb
Published 2013-01-01

PAR-2 Deficient CD4+ T Cells Exhibit Downregulation of IL-4 and Upregulation of IFN-γ after Antigen Challenge in Mice

by Michitaka Shichijo, Shinichi Kondo, Mina Ishimori, Shinichi Watanabe, Heidi Helin, Tsugiko Yamasaki, Mary E Stevens, Florian Gantner, Kevin B Bacon
Published 2006-01-01

Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96‑Transwell air–liquid interface model

by Teresa Bluhmki, Stefanie Traub, Ann-Kathrin Müller, Sarah Bitzer, Eva Schruf, Marie-Therese Bammert, Marcel Leist, Florian Gantner, James P Garnett, Ralf Heilker
Published 2021-08-01

Cigarette Smoke Specifically Affects Small Airway Epithelial Cell Populations and Triggers the Expansion of Inflammatory and Squamous Differentiation Associated Basal Cells

by Christian T. Wohnhaas, Julia A. Gindele, Tobias Kiechle, Yang Shen, Germán G. Leparc, Birgit Stierstorfer, Heiko Stahl, Florian Gantner, Coralie Viollet, Jürgen Schymeinsky, Patrick Baum
Published 2021-07-01

IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice

by Carolin K. Koss, Christian T. Wohnhaas, Jonathan R. Baker, Cornelia Tilp, Michèl Przibilla, Carmen Lerner, Silvia Frey, Martina Keck, Cara M. M. Williams, Daniel Peter, Meera Ramanujam, Jay Fine, Florian Gantner, Matthew Thomas, Peter J. Barnes, Louise E. Donnelly, Karim C. El Kasmi
Published 2021-02-01

Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization.

by Patrick Baum, Ramona Schmid, Carina Ittrich, Werner Rust, Katrin Fundel-Clemens, Susanne Siewert, Martin Baur, Lisa Mara, Lore Gruenbaum, Armin Heckel, Roland Eils, Roland E Kontermann, Gerald J Roth, Florian Gantner, Andreas Schnapp, John E Park, Andreas Weith, Karsten Quast, Detlev Mennerich
Published 2010-12-01