An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory polyarthrit...

by Niki Karagianni, Ksanthi Kranidioti, Nikolaos Fikas, Maria Tsochatzidou, Panagiotis Chouvardas, Maria C Denis, George Kollias, Christoforos Nikolaou
Published 2019-05-01

Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment

by Lydia Ntari, Christoforos Nikolaou, Ksanthi Kranidioti, Dimitra Papadopoulou, Eleni Christodoulou-Vafeiadou, Panagiotis Chouvardas, Florian Meier, Christina Geka, Maria C. Denis, Niki Karagianni, George Kollias
Published 2021-04-01

Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects agains...

by Irini Papazian, Eleni Tsoukala, Athena Boutou, Maria Karamita, Konstantinos Kambas, Lida Iliopoulou, Roman Fischer, Roland E. Kontermann, Maria C. Denis, George Kollias, Hans Lassmann, Lesley Probert
Published 2021-09-01

Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis

by Eleni Christodoulou-Vafeiadou, Christina Geka, Lydia Ntari, Ksanthi Kranidioti, Eleni Argyropoulou, Florian Meier, Marietta Armaka, Iordanis Mourouzis, Constantinos Pantos, Maritina Rouchota, George Loudos, Maria C. Denis, Niki Karagianni, George Kollias
Published 2020-10-01