Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes

by Matthias Pawlowski, Daniel Ortmann, Alessandro Bertero, Joana M. Tavares, Roger A. Pedersen, Ludovic Vallier, Mark R.N. Kotter
Published 2017-04-01

Activin/Nodal Signaling Supports Retinal Progenitor Specification in a Narrow Time Window during Pluripotent Stem Cell Neuralization

by Michele Bertacchi, Giuseppe Lupo, Luca Pandolfini, Simona Casarosa, Mara D’Onofrio, Roger A. Pedersen, William A. Harris, Federico Cremisi
Published 2015-10-01

Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells.

by Amanda L Evans, Tiago Faial, Michael J Gilchrist, Thomas Down, Ludovic Vallier, Roger A Pedersen, Fiona C Wardle, James C Smith
Published 2012-01-01

Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic ste...

by Giuseppe Lupo, Claire Novorol, Joseph R. Smith, Ludovic Vallier, Elena Miranda, Morgan Alexander, Stefano Biagioni, Roger A. Pedersen, William A. Harris
Published 2013-01-01

Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways.

by Ludovic Vallier, Thomas Touboul, Zhenzhi Chng, Minodora Brimpari, Nicholas Hannan, Enrique Millan, Lucy E Smithers, Matthew Trotter, Peter Rugg-Gunn, Anne Weber, Roger A Pedersen
Published 2009-06-01

Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states

by René A. M. Dirks, Guido van Mierlo, Hindrik H. D. Kerstens, Andreia S. Bernardo, Julianna Kobolák, István Bock, Julien Maruotti, Roger A. Pedersen, András Dinnyés, Martijn A. Huynen, Alice Jouneau, Hendrik Marks
Published 2019-02-01

Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells

by Aster H. Juan, Stan Wang, Kyung Dae Ko, Hossein Zare, Pei-Fang Tsai, Xuesong Feng, Karinna O. Vivanco, Anthony M. Ascoli, Gustavo Gutierrez-Cruz, Jordan Krebs, Simone Sidoli, Adam L. Knight, Roger A. Pedersen, Benjamin A. Garcia, Rafael Casellas, Jizhong Zou, Vittorio Sartorelli
Published 2016-10-01

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

by Thomas Moreau, Amanda L. Evans, Louella Vasquez, Marloes R. Tijssen, Ying Yan, Matthew W. Trotter, Daniel Howard, Maria Colzani, Meera Arumugam, Wing Han Wu, Amanda Dalby, Riina Lampela, Guenaelle Bouet, Catherine M. Hobbs, Dean C. Pask, Holly Payne, Tatyana Ponomaryov, Alexander Brill, Nicole Soranzo, Willem H. Ouwehand, Roger A. Pedersen, Cedric Ghevaert
Published 2016-04-01

Correction: Corrigendum: Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

by Thomas Moreau, Amanda L. Evans, Louella Vasquez, Marloes R. Tijssen, Ying Yan, Matthew W. Trotter, Daniel Howard, Maria Colzani, Meera Arumugam, Wing Han Wu, Amanda Dalby, Riina Lampela, Guenaelle Bouet, Catherine M. Hobbs, Dean C. Pask, Holly Payne, Tatyana Ponomaryov, Alexander Brill, Nicole Soranzo, Willem H. Ouwehand, Roger A. Pedersen, Cedric Ghevaert
Published 2017-07-01

Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state

by Andreia S. Bernardo, Alice Jouneau, Hendrik Marks, Philip Kensche, Julianna Kobolak, Kristine Freude, Vanessa Hall, Anita Feher, Zsuzsanna Polgar, Chiara Sartori, Istvan Bock, Claire Louet, Tiago Faial, Hindrik H. D. Kerstens, Camille Bouissou, Gregory Parsonage, Kaveh Mashayekhi, James C. Smith, Giovanna Lazzari, Poul Hyttel, Hendrik G. Stunnenberg, Martijn Huynen, Roger A. Pedersen, Andras Dinnyes
Published 2018-08-01