Assessment of intrinsic and extrinsic signaling pathway in excitotoxic retinal ganglion cell death

by Berkeley K. Fahrenthold, Kimberly A. Fernandes, Richard T. Libby
Published 2018-03-01

Ciliary margin-derived BMP4 does not have a major role in ocular development.

by Rebecca L Rausch, Richard T Libby, Amy E Kiernan
Published 2018-01-01

DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury

by Kimberly A. Fernandes, Jeffrey M. Harder, Simon W. John, Peter Shrager, Richard T. Libby
Published 2014-09-01

Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury

by Stephanie B. Syc-Mazurek, Kimberly A. Fernandes, Michael P. Wilson, Peter Shrager, Richard T. Libby
Published 2017-10-01

Salinomycin inhibits proliferative vitreoretinopathy formation in a mouse model.

by Alison M Heffer, Victor Wang, Richard T Libby, Steven E Feldon, Collynn F Woeller, Ajay E Kuriyan
Published 2020-01-01

DBA/2J mice are susceptible to diabetic nephropathy and diabetic exacerbation of IOP elevation.

by Ileana Soto, Gareth R Howell, Cai W John, Joseph L Kief, Richard T Libby, Simon W M John
Published 2014-01-01

Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage.

by Richard T Libby, Yan Li, Olga V Savinova, Joseph Barter, Richard S Smith, Robert W Nickells, Simon W M John
Published 2005-07-01

Mutations in a P-type ATPase gene cause axonal degeneration.

by Xianjun Zhu, Richard T Libby, Wilhelmine N de Vries, Richard S Smith, Dana L Wright, Roderick T Bronson, Kevin L Seburn, Simon W M John
Published 2012-01-01

JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death

by Kimberly A. Fernandes, Jeffrey M. Harder, Laura B. Fornarola, Robert S. Freeman, Abbot F. Clark, Iok-Hou Pang, Simon W.M. John, Richard T. Libby
Published 2012-05-01

The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology.

by Alison M Heffer, Jacob Proaño, Elisa Roztocil, Richard P Phipps, Steven E Feldon, Krystel R Huxlin, Patricia J Sime, Richard T Libby, Collynn F Woeller, Ajay E Kuriyan
Published 2019-01-01