The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear.

by Amy E Kiernan, Jingxia Xu, Thomas Gridley
Published 2006-01-01

Ciliary margin-derived BMP4 does not have a major role in ocular development.

by Rebecca L Rausch, Richard T Libby, Amy E Kiernan
Published 2018-01-01

SOX2 is required for inner ear neurogenesis

by Aleta R. Steevens, Danielle L. Sookiasian, Jenna C. Glatzer, Amy E. Kiernan
Published 2017-06-01

Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells.

by Grace Savoy-Burke, Felicia A Gilels, Wei Pan, Diana Pratt, Jianwen Que, Lin Gan, Patricia M White, Amy E Kiernan
Published 2014-01-01

Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects.

by Georg Steffes, Beatriz Lorente-Cánovas, Selina Pearson, Rachael H Brooker, Sarah Spiden, Amy E Kiernan, Jean-Louis Guénet, Karen P Steel
Published 2012-01-01