Glycoform and net charge heterogeneity in gp120 immunogens used in HIV vaccine trials.

by Bin Yu, Javier F Morales, Sara M O'Rourke, Gwen P Tatsuno, Phillip W Berman
Published 2012-01-01

Monoclonal antibodies to the V2 domain of MN-rgp120: fine mapping of epitopes and inhibition of α4β7 binding.

by Gerald R Nakamura, Dora P A J Fonseca, Sara M O'Rourke, Aaron L Vollrath, Phillip W Berman
Published 2012-01-01

Phylodynamics of HIV-1 from a phase III AIDS vaccine trial in Bangkok, Thailand.

by Marcos Pérez-Losada, David V Jobes, Faruk Sinangil, Keith A Crandall, Miguel Arenas, David Posada, Phillip W Berman
Published 2011-03-01

Glycan modifications to the gp120 immunogens used in the RV144 vaccine trial improve binding to broadly neutralizing antibodies.

by Rachel C Doran, Gwen P Tatsuno, Sara M O'Rourke, Bin Yu, David L Alexander, Kathryn A Mesa, Phillip W Berman
Published 2018-01-01

Comparative immunogenicity of HIV-1 clade C envelope proteins for prime/boost studies.

by Douglas H Smith, Peggy Winters-Digiacinto, Misrach Mitiku, Sara O'Rourke, Faruk Sinangil, Terri Wrin, David C Montefiori, Phillip W Berman
Published 2010-08-01

Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens.

by Sophia W Li, Meredith Wright, John F Healey, Jennie M Hutchinson, Sara O'Rourke, Kathryn A Mesa, Pete Lollar, Phillip W Berman
Published 2020-01-01

Peptide Targeted by Human Antibodies Associated with HIV Vaccine-Associated Protection Assumes a Dynamic α-Helical Structure.

by Mohammed S Aiyegbo, Evgeny Shmelkov, Lorenzo Dominguez, Michael Goger, Shibani Battacharya, Allan C deCamp, Peter B Gilbert, Phillip W Berman, Timothy Cardozo
Published 2017-01-01

Robotic selection for the rapid development of stable CHO cell lines for HIV vaccine production.

by Sara M O'Rourke, Gabriel Byrne, Gwen Tatsuno, Meredith Wright, Bin Yu, Kathryn A Mesa, Rachel C Doran, David Alexander, Phillip W Berman
Published 2018-01-01

CRISPR/Cas9 gene editing for the creation of an MGAT1-deficient CHO cell line to control HIV-1 vaccine glycosylation.

by Gabriel Byrne, Sara M O'Rourke, David L Alexander, Bin Yu, Rachel C Doran, Meredith Wright, Qiushi Chen, Parastoo Azadi, Phillip W Berman
Published 2018-08-01

Glycans flanking the hypervariable connecting peptide between the A and B strands of the V1/V2 domain of HIV-1 gp120 confer resistance to antibodies that neutralize CRF01_AE viruse...

by Sara M O'Rourke, Ruengpung Sutthent, Pham Phung, Kathryn A Mesa, Normand L Frigon, Briana To, Navin Horthongkham, Kay Limoli, Terri Wrin, Phillip W Berman
Published 2015-01-01

Unusual Cysteine Content in V1 Region of gp120 From an Elite Suppressor That Produces Broadly Neutralizing Antibodies

by Jennie M. Hutchinson, Kathryn A. Mesa, David L. Alexander, Bin Yu, Sara M. O'Rourke, Kay L. Limoli, Terri Wrin, Steven G. Deeks, Phillip W. Berman
Published 2019-05-01

Development of a Stable MGAT1− CHO Cell Line to Produce Clade C gp120 With Improved Binding to Broadly Neutralizing Antibodies

by Rachel C. Doran, Rachel C. Doran, Bin Yu, Meredith Wright, Sara M. O'Rourke, Lu Yin, Jennie M. Richardson, Gabriel Byrne, Kathryn A. Mesa, Phillip W. Berman
Published 2018-10-01

Ancestral sequences from an elite neutralizer proximal to the development of neutralization resistance as a potential source of HIV vaccine immunogens.

by Kathryn A Mesa, Bin Yu, Terri Wrin, Christos J Petropoulos, Grant H Pogson, David L Alexander, Gerardo Perez, Sara M O'Rourke, Faruk Sinangil, Joseph Robinson, Marcus A Conant, Phillip W Berman
Published 2019-01-01

V1V2-specific complement activating serum IgG as a correlate of reduced HIV-1 infection risk in RV144.

by Lautaro G Perez, David R Martinez, Allan C deCamp, Abraham Pinter, Phillip W Berman, Donald Francis, Faruk Sinangil, Carter Lee, Kelli Greene, Hongmei Gao, Sorachai Nitayaphan, Supachai Rerks-Ngarm, Jaranit Kaewkungwal, Punnee Pitisuttithum, James Tartaglia, Robert J O'Connell, Merlin L Robb, Nelson L Michael, Jerome H Kim, Peter Gilbert, David C Montefiori
Published 2017-01-01

Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women.

by Peter B Gilbert, Jean-Louis Excler, Georgia D Tomaras, Lindsay N Carpp, Barton F Haynes, Hua-Xin Liao, David C Montefiori, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Jaranit Kaewkungwal, Gustavo H Kijak, Sodsai Tovanabutra, Donald P Francis, Carter Lee, Faruk Sinangil, Phillip W Berman, Nakorn Premsri, Prayura Kunasol, Robert J O'Connell, Nelson L Michael, Merlin L Robb, Rhoda Morrow, Lawrence Corey, Jerome H Kim
Published 2017-01-01

Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk of infection in the RV144 vaccine efficacy trial.

by Raphael Gottardo, Robert T Bailer, Bette T Korber, S Gnanakaran, Joshua Phillips, Xiaoying Shen, Georgia D Tomaras, Ellen Turk, Gregory Imholte, Larry Eckler, Holger Wenschuh, Johannes Zerweck, Kelli Greene, Hongmei Gao, Phillip W Berman, Donald Francis, Faruk Sinangil, Carter Lee, Sorachai Nitayaphan, Supachai Rerks-Ngarm, Jaranit Kaewkungwal, Punnee Pitisuttithum, James Tartaglia, Merlin L Robb, Nelson L Michael, Jerome H Kim, Susan Zolla-Pazner, Barton F Haynes, John R Mascola, Steve Self, Peter Gilbert, David C Montefiori
Published 2013-01-01