Beneficial effects of alternate dietary regimen on liver inflammation, atherosclerosis and renal activation.

by Peter Y Wielinga, Gopala K Yakala, Peter Heeringa, Robert Kleemann, Teake Kooistra
Published 2011-01-01

Vaccination against GIP for the treatment of obesity.

by Alma Fulurija, Thomas A Lutz, Katja Sladko, Melania Osto, Peter Y Wielinga, Martin F Bachmann, Philippe Saudan
Published 2008-01-01

Beneficial effects of an alternating high- fat dietary regimen on systemic insulin resistance, hepatic and renal inflammation and renal function.

by Gopala K Yakala, Roel van der Heijden, Grietje Molema, Martin Schipper, Peter Y Wielinga, Robert Kleemann, Teake Kooistra, Peter Heeringa
Published 2012-01-01

A casein hydrolysate based formulation attenuates obesity and associated non-alcoholic fatty liver disease and atherosclerosis in LDLr-/-.Leiden mice.

by Marieke H Schoemaker, Robert Kleemann, Martine C Morrison, Joanne Verheij, Kanita Salic, Eric A F van Tol, Teake Kooistra, Peter Y Wielinga
Published 2017-01-01

Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of V...

by Martine C Morrison, Petra Mulder, P Mark Stavro, Manuel Suárez, Anna Arola-Arnal, Wim van Duyvenvoorde, Teake Kooistra, Peter Y Wielinga, Robert Kleemann
Published 2015-01-01

Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?

by Martine C. Morrison, Gopala K. Yakala, Wen Liang, Peter Y. Wielinga, Kanita Salic, Arianne van Koppen, Tushar Tomar, Robert Kleemann, Peter Heeringa, Teake Kooistra
Published 2017-06-01

Combined Treatment with L-Carnitine and Nicotinamide Riboside Improves Hepatic Metabolism and Attenuates Obesity and Liver Steatosis

by Kanita Salic, Eveline Gart, Florine Seidel, Lars Verschuren, Martien Caspers, Wim van Duyvenvoorde, Kari E. Wong, Jaap Keijer, Ivana Bobeldijk-Pastorova, Peter Y. Wielinga, Robert Kleemann
Published 2019-09-01

Coordinated and interactive expression of genes of lipid metabolism and inflammation in adipose tissue and liver during metabolic overload.

by Wen Liang, Giulia Tonini, Petra Mulder, Thomas Kelder, Marjan van Erk, Anita M van den Hoek, Rob Mariman, Peter Y Wielinga, Michela Baccini, Teake Kooistra, Annibale Biggeri, Robert Kleemann
Published 2013-01-01

Differential effects of drug interventions and dietary lifestyle in developing type 2 diabetes and complications: a systems biology analysis in LDLr-/- mice.

by Marijana Radonjic, Peter Y Wielinga, Suzan Wopereis, Thomas Kelder, Varshna S Goelela, Lars Verschuren, Karin Toet, Wim van Duyvenvoorde, Bianca van der Werff van der Vat, Johanna H M Stroeve, Nicole Cnubben, Teake Kooistra, Ben van Ommen, Robert Kleemann
Published 2013-01-01

Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance.

by Robert Kleemann, Marjan van Erk, Lars Verschuren, Anita M van den Hoek, Maud Koek, Peter Y Wielinga, Annie Jie, Linette Pellis, Ivana Bobeldijk-Pastorova, Thomas Kelder, Karin Toet, Suzan Wopereis, Nicole Cnubben, Chris Evelo, Ben van Ommen, Teake Kooistra
Published 2010-01-01

Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr‐/‐.Leiden Mice

by Martine C. Morrison, Lars Verschuren, Kanita Salic, Joanne Verheij, Aswin Menke, Peter Y. Wielinga, Marta Iruarrizaga‐Lejarreta, Laurent Gole, Wei‐Miao Yu, Scott Turner, Martien P.M. Caspers, Ibon Martínez‐Arranz, Elsbet Pieterman, Reinout Stoop, Arianne van Koppen, Anita M. van den Hoek, José M. Mato, Roeland Hanemaaijer, Cristina Alonso, Robert Kleemann
Published 2018-12-01