Key Inflammatory Processes in Human NASH Are Reflected in Ldlr−/−.Leiden Mice: A Translational Gene Profiling Study

by Martine C. Morrison, Robert Kleemann, Robert Kleemann, Arianne van Koppen, Roeland Hanemaaijer, Lars Verschuren
Published 2018-02-01

Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases

by Gustav Holmgren, Benjamin Ulfenborg, Annika Asplund, Karin Toet, Christian X Andersson, Ann Hammarstedt, Roeland Hanemaaijer, Barbara Küppers-Munther, Jane Synnergren
Published 2020-01-01

Identification of free nitric oxide radicals in rat bone marrow: implications for progenitor cell mobilization in hypertension.

by Marina A Aleksinskaya, Ernst E H van Faassen, Jelly Nelissen, Ben J A Janssen, Jo G R De Mey, Roeland Hanemaaijer, Ton Rabelink, Anton Jan van Zonneveld
Published 2013-01-01

A clinical evaluation of statin pleiotropy: statins selectively and dose-dependently reduce vascular inflammation.

by Evelien van der Meij, Giel G Koning, Patrick W Vriens, Marcel F Peeters, C Arnoud Meijer, Kim E Kortekaas, Ronald L Dalman, J Hajo van Bockel, Roeland Hanemaaijer, Teake Kooistra, Robert Kleemann, Jan H N Lindeman
Published 2013-01-01

Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr‐/‐.Leiden Mice

by Martine C. Morrison, Lars Verschuren, Kanita Salic, Joanne Verheij, Aswin Menke, Peter Y. Wielinga, Marta Iruarrizaga‐Lejarreta, Laurent Gole, Wei‐Miao Yu, Scott Turner, Martien P.M. Caspers, Ibon Martínez‐Arranz, Elsbet Pieterman, Reinout Stoop, Arianne van Koppen, Anita M. van den Hoek, José M. Mato, Roeland Hanemaaijer, Cristina Alonso, Robert Kleemann
Published 2018-12-01

Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model

by Arianne van Koppen, Lars Verschuren, Anita M. van den Hoek, Joanne Verheij, Martine C. Morrison, Kelvin Li, Hiroshi Nagabukuro, Adalberto Costessi, Martien P.M. Caspers, Tim J. van den Broek, John Sagartz, Cornelis Kluft, Carine Beysen, Claire Emson, Alain J. van Gool, Roel Goldschmeding, Reinout Stoop, Ivana Bobeldijk-Pastorova, Scott M. Turner, Guido Hanauer, Roeland Hanemaaijer
Published 2018-01-01