Cholesterol Accumulation as a Driver of Hepatic Inflammation Under Translational Dietary Conditions Can Be Attenuated by a Multicomponent Medicine

by Andrea M. Mueller, Robert Kleemann, Robert Kleemann, Eveline Gart, Eveline Gart, Wim van Duyvenvoorde, Lars Verschuren, Martien Caspers, Aswin Menke, Natascha Krömmelbein, Kanita Salic, Yvonne Burmeister, Bernd Seilheimer, Martine C. Morrison, Martine C. Morrison
Published 2021-03-01

Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr‐/‐.Leiden Mice

by Martine C. Morrison, Lars Verschuren, Kanita Salic, Joanne Verheij, Aswin Menke, Peter Y. Wielinga, Marta Iruarrizaga‐Lejarreta, Laurent Gole, Wei‐Miao Yu, Scott Turner, Martien P.M. Caspers, Ibon Martínez‐Arranz, Elsbet Pieterman, Reinout Stoop, Arianne van Koppen, Anita M. van den Hoek, José M. Mato, Roeland Hanemaaijer, Cristina Alonso, Robert Kleemann
Published 2018-12-01