Population-Level Analysis to Determine Parameters That Drive Variation in the Plasma Metabolite Profiles

by Mahmoud Al-Majdoub, Katharina Herzog, Bledar Daka, Martin Magnusson, Lennart Råstam, Ulf Lindblad, Peter Spégel
Published 2018-11-01

The transcriptional co-repressor myeloid translocation gene 16 inhibits glycolysis and stimulates mitochondrial respiration.

by Parveen Kumar, Vladimir V Sharoyko, Peter Spégel, Urban Gullberg, Hindrik Mulder, Inge Olsson, Ram Ajore
Published 2013-01-01

Discriminative Prediction of A-To-I RNA Editing Events from DNA Sequence.

by Jiangming Sun, Yang De Marinis, Peter Osmark, Pratibha Singh, Annika Bagge, Bérengère Valtat, Petter Vikman, Peter Spégel, Hindrik Mulder
Published 2016-01-01

Probiotic fruit beverages with different polyphenol profiles attenuated early insulin response

by Jie Xu, Tommy Jönsson, Merichel Plaza, Åsa Håkansson, Martin Antonsson, Irini Lazou Ahrén, Charlotta Turner, Peter Spégel, Yvonne Granfeldt
Published 2018-02-01

Characterization of stimulus-secretion coupling in the human pancreatic EndoC-βH1 beta cell line.

by Lotta E Andersson, Bérengère Valtat, Annika Bagge, Vladimir V Sharoyko, David G Nicholls, Philippe Ravassard, Raphael Scharfmann, Peter Spégel, Hindrik Mulder
Published 2015-01-01

NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells

by Laila R.B. Santos, Carole Muller, Arnaldo H. de Souza, Hilton K. Takahashi, Peter Spégel, Ian R. Sweet, Heeyoung Chae, Hindrik Mulder, Jean-Christophe Jonas
Published 2017-06-01

The impact of Roux-en-Y gastric bypass surgery on normal metabolism in a porcine model.

by Andreas Lindqvist, Mikael Ekelund, Eliana Garcia-Vaz, Marcus Ståhlman, Stefan Pierzynowski, Maria F Gomez, Jens F Rehfeld, Leif Groop, Jan Hedenbro, Nils Wierup, Peter Spégel
Published 2017-01-01

Inhibition of nuclear factor of activated T-cells (NFAT) suppresses accelerated atherosclerosis in diabetic mice.

by Anna V Zetterqvist, Lisa M Berglund, Fabiana Blanco, Eliana Garcia-Vaz, Maria Wigren, Pontus Dunér, Anna-Maria Dutius Andersson, Fong To, Peter Spegel, Jan Nilsson, Eva Bengtsson, Maria F Gomez
Published 2014-01-01

Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes

by Julie Adam, Reshma Ramracheya, Margarita V. Chibalina, Nicola Ternette, Alexander Hamilton, Andrei I. Tarasov, Quan Zhang, Eduardo Rebelato, Nils J.G. Rorsman, Rafael Martín-del-Río, Amy Lewis, Gizem Özkan, Hyun Woong Do, Peter Spégel, Kaori Saitoh, Keiko Kato, Kaori Igarashi, Benedikt M. Kessler, Christopher W. Pugh, Jorge Tamarit-Rodriguez, Hindrik Mulder, Anne Clark, Norma Frizzell, Tomoyoshi Soga, Frances M. Ashcroft, Andrew Silver, Patrick J. Pollard, Patrik Rorsman
Published 2017-09-01