The Succinated Proteome of FH-Mutant Tumours

by Ming Yang, Nicola Ternette, Huizhong Su, Raliat Dabiri, Benedikt M. Kessler, Julie Adam, Bin Tean Teh, Patrick J. Pollard
Published 2014-08-01

Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α).

by Armin Thalhammer, Zuzana Bencokova, Rachel Poole, Christoph Loenarz, Julie Adam, Linda O'Flaherty, Johannes Schödel, David Mole, Konstantinos Giaslakiotis, Christopher J Schofield, Ester M Hammond, Peter J Ratcliffe, Patrick J Pollard
Published 2011-01-01

Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency

by Nicola Ternette, Ming Yang, Mahima Laroyia, Mitsuhiro Kitagawa, Linda O’Flaherty, Kathryn Wolhulter, Kaori Igarashi, Kaori Saito, Keiko Kato, Roman Fischer, Alexandre Berquand, Benedikt M. Kessler, Terry Lappin, Norma Frizzell, Tomoyoshi Soga, Julie Adam, Patrick J. Pollard
Published 2013-03-01

A Role for Cytosolic Fumarate Hydratase in Urea Cycle Metabolism and Renal Neoplasia

by Julie Adam, Ming Yang, Christina Bauerschmidt, Mitsuhiro Kitagawa, Linda O’Flaherty, Pratheesh Maheswaran, Gizem Özkan, Natasha Sahgal, Dilair Baban, Keiko Kato, Kaori Saito, Keiko Iino, Kaori Igarashi, Michael Stratford, Christopher Pugh, Daniel A. Tennant, Christian Ludwig, Benjamin Davies, Peter J. Ratcliffe, Mona El-Bahrawy, Houman Ashrafian, Tomoyoshi Soga, Patrick J. Pollard
Published 2013-05-01

Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes

by Julie Adam, Reshma Ramracheya, Margarita V. Chibalina, Nicola Ternette, Alexander Hamilton, Andrei I. Tarasov, Quan Zhang, Eduardo Rebelato, Nils J.G. Rorsman, Rafael Martín-del-Río, Amy Lewis, Gizem Özkan, Hyun Woong Do, Peter Spégel, Kaori Saitoh, Keiko Kato, Kaori Igarashi, Benedikt M. Kessler, Christopher W. Pugh, Jorge Tamarit-Rodriguez, Hindrik Mulder, Anne Clark, Norma Frizzell, Tomoyoshi Soga, Frances M. Ashcroft, Andrew Silver, Patrick J. Pollard, Patrik Rorsman
Published 2017-09-01