Regulation of Rho GTPases in the Vasculature by Cullin3-Based E3 Ligase Complexes

by Fabienne Podieh, Peter L. Hordijk
Published 2021-05-01

The interplay of Rac1 activity, ubiquitination and GDI binding and its consequences for endothelial cell spreading.

by Jisca Majolée, Fabienne Podieh, Peter L Hordijk, Igor Kovačević
Published 2021-01-01

The presence of alpha-catenin in the VE-cadherin complex is required for efficient transendothelial migration of leukocytes

by Jaap D. van Buul, Floris P. van Alphen, Peter L. Hordijk
Published 2009-01-01

Rho GTPase expression in human myeloid cells.

by Suzanne F G van Helden, Eloise C Anthony, Rob Dee, Peter L Hordijk
Published 2012-01-01

Nucleophosmin1 is a negative regulator of the small GTPase Rac1.

by Younes Zoughlami, Anne M van Stalborgh, Paula B van Hennik, Peter L Hordijk
Published 2013-01-01

The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion.

by Jos van Rijssel, Mark Hoogenboezem, Lynn Wester, Peter L Hordijk, Jaap D Van Buul
Published 2012-01-01

A functional siRNA screen identifies RhoGTPase-associated genes involved in thrombin-induced endothelial permeability.

by Joana Amado-Azevedo, Renee X de Menezes, Geerten P van Nieuw Amerongen, Victor W M van Hinsbergh, Peter L Hordijk
Published 2018-01-01

Plasminogen Activator Inhibitor-1 Controls Vascular Integrity by Regulating VE-Cadherin Trafficking.

by Anna E Daniel, Ilse Timmerman, Igor Kovacevic, Peter L Hordijk, Luc Adriaanse, Ilkka Paatero, Heinz-Georg Belting, Jaap D van Buul
Published 2015-01-01

Altered intracellular localization and mobility of SBDS protein upon mutation in Shwachman-Diamond syndrome.

by Claudia Orelio, Renée M van der Sluis, Paul Verkuijlen, Micha Nethe, Peter L Hordijk, Timo K van den Berg, Taco W Kuijpers
Published 2011-01-01

A New Generation of FRET Sensors for Robust Measurement of Gαi1, Gαi2 and Gαi3 Activation Kinetics in Single Cells.

by Jakobus van Unen, Anette D Stumpf, Benedikt Schmid, Nathalie R Reinhard, Peter L Hordijk, Carsten Hoffmann, Theodorus W J Gadella, Joachim Goedhart
Published 2016-01-01

Correction: Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor.

by Michel W J Smeets, Ruben Bierings, Henriet Meems, Frederik P J Mul, Dirk Geerts, Alexander P J Vlaar, Jan Voorberg, Peter L Hordijk
Published 2018-01-01

ICAM-1 Clustering on Endothelial Cells Recruits VCAM-1

by Jaap D. van Buul, Jos van Rijssel, Floris P. J. van Alphen, Anna-Marieke van Stalborch, Erik P. J. Mul, Peter L. Hordijk
Published 2010-01-01

Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor.

by Michel W J Smeets, Ruben Bierings, Henriet Meems, Frederik P J Mul, Dirk Geerts, Alexander P J Vlaar, Jan Voorberg, Peter L Hordijk
Published 2017-01-01

The human minor histocompatibility antigen 1 is a RhoGAP.

by Bart-Jan de Kreuk, Antje Schaefer, Eloise C Anthony, Simon Tol, Mar Fernandez-Borja, Dirk Geerts, Jos Pool, Lothar Hambach, Els Goulmy, Peter L Hordijk
Published 2013-01-01

Inside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endothelium.

by Jaap D van Buul, Jos van Rijssel, Floris P J van Alphen, Mark Hoogenboezem, Simon Tol, Kees A Hoeben, Jan van Marle, Erik P J Mul, Peter L Hordijk
Published 2010-06-01

Early-onset preeclampsia predisposes to preclinical diastolic left ventricular dysfunction in the fifth decade of life: An observational study.

by Anouk Bokslag, Constantijn Franssen, Lisa J Alma, Igor Kovacevic, Floortje van Kesteren, Pim W Teunissen, Otto Kamp, Wessel Ganzevoort, Peter L Hordijk, Christianne J M de Groot, Walter J Paulus
Published 2018-01-01

Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-...

by Nicole A. M. Dekker, Anoek L. I. van Leeuwen, Willem W. J. van Strien, Jisca Majolée, Robert Szulcek, Alexander B. A. Vonk, Peter L. Hordijk, Christa Boer, Charissa E. van den Brom
Published 2019-04-01

Microembolus clearance through angiophagy is an auxiliary mechanism preserving tissue perfusion in the rat brain

by Anne-Eva van der Wijk, Theodosia Georgakopoulou, Jisca Majolée, Jan S. M. van Bezu, Miesje M. van der Stoel, Bert J. van het Hof, Helga E. de Vries, Stephan Huveneers, Peter L. Hordijk, Erik N. T. P. Bakker, Ed van Bavel
Published 2020-11-01

The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions

by Yvonne L. Dorland, Tsveta S. Malinova, Anne-Marieke D. van Stalborch, Adam G. Grieve, Daphne van Geemen, Nicolette S. Jansen, Bart-Jan de Kreuk, Kalim Nawaz, Jeroen Kole, Dirk Geerts, René J. P. Musters, Johan de Rooij, Peter L. Hordijk, Stephan Huveneers
Published 2016-07-01

Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental cardiopulmonary bypass

by Nicole A. M. Dekker, Anoek L. I. van Leeuwen, Matijs van Meurs, Jill Moser, Jeannette E. Pankras, Nicole N. van der Wel, Hans W. Niessen, Marc G. Vervloet, Alexander B. A. Vonk, Peter L. Hordijk, Christa Boer, Charissa E. van den Brom
Published 2021-06-01