The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion.

by Jos van Rijssel, Mark Hoogenboezem, Lynn Wester, Peter L Hordijk, Jaap D Van Buul
Published 2012-01-01

The RhoGEF Trio: A Protein with a Wide Range of Functions in the Vascular Endothelium

by Lanette Kempers, Amber J. M. Driessen, Jos van Rijssel, Martijn A. Nolte, Jaap D. van Buul
Published 2021-09-01

ICAM-1 Clustering on Endothelial Cells Recruits VCAM-1

by Jaap D. van Buul, Jos van Rijssel, Floris P. J. van Alphen, Anna-Marieke van Stalborch, Erik P. J. Mul, Peter L. Hordijk
Published 2010-01-01

Inside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endothelium.

by Jaap D van Buul, Jos van Rijssel, Floris P J van Alphen, Mark Hoogenboezem, Simon Tol, Kees A Hoeben, Jan van Marle, Erik P J Mul, Peter L Hordijk
Published 2010-06-01

The Rho-GEF Trio regulates a novel pro-inflammatory pathway through the transcription factor Ets2

by Jos Van Rijssel, Ilse Timmerman, Floris P. J. Van Alphen, Mark Hoogenboezem, Olexandr Korchynskyi, Dirk Geerts, Judy Geissler, Kris A. Reedquist, Hans W. M. Niessen, Jaap D. Van Buul
Published 2013-04-01

F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling

by Niels Heemskerk, Lilian Schimmel, Chantal Oort, Jos van Rijssel, Taofei Yin, Bin Ma, Jakobus van Unen, Bettina Pitter, Stephan Huveneers, Joachim Goedhart, Yi Wu, Eloi Montanez, Abigail Woodfin, Jaap D. van Buul
Published 2016-01-01

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models

by Alina Klems, Jos van Rijssel, Anne S. Ramms, Raphael Wild, Julia Hammer, Melanie Merkel, Laura Derenbach, Laetitia Préau, Rabea Hinkel, Irina Suarez-Martinez, Stefan Schulte-Merker, Ramon Vidal, Sascha Sauer, Riikka Kivelä, Kari Alitalo, Christian Kupatt, Jaap D. van Buul, Ferdinand le Noble
Published 2020-10-01

Stiffness-Induced Endothelial DLC-1 Expression Forces Leukocyte Spreading through Stabilization of the ICAM-1 Adhesome

by Lilian Schimmel, Miesje van der Stoel, Carmela Rianna, Anne-Marieke van Stalborch, Aafke de Ligt, Mark Hoogenboezem, Simon Tol, Jos van Rijssel, Robert Szulcek, Harm Jan Bogaard, Patrick Hofmann, Reinier Boon, Manfred Radmacher, Vivian de Waard, Stephan Huveneers, Jaap D. van Buul
Published 2018-09-01

Human B Cells Engage the NCK/PI3K/RAC1 Axis to Internalize Large Particles via the IgM-BCR

by Niels J. M. Verstegen, Niels J. M. Verstegen, Peter-Paul A. Unger, Julia Z. Walker, Benoit P. Nicolet, Tineke Jorritsma, Jos van Rijssel, Robbert M. Spaapen, Jelle de Wit, Jaap D. van Buul, Anja ten Brinke, S. Marieke van Ham, S. Marieke van Ham
Published 2019-03-01

Endothelial Focal Adhesions Are Functional Obstacles for Leukocytes During Basolateral Crawling

by Janine J. G. Arts, Janine J. G. Arts, Eike K. Mahlandt, Lilian Schimmel, Max L. B. Grönloh, Sanne van der Niet, Bart J. A. M. Klein, Mar Fernandez-Borja, Daphne van Geemen, Stephan Huveneers, Jos van Rijssel, Joachim Goedhart, Jaap D. van Buul, Jaap D. van Buul
Published 2021-05-01

Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration

by Janine JG Arts, Eike K Mahlandt, Max LB Grönloh, Lilian Schimmel, Ivar Noordstra, Emma Gordon, Abraham CI van Steen, Simon Tol, Barbara Walzog, Jos van Rijssel, Martijn A Nolte, Marten Postma, Satya Khuon, John M Heddleston, Eric Wait, Teng Leong Chew, Mark Winter, Eloi Montanez, Joachim Goedhart, Jaap D van Buul
Published 2021-08-01