Critical Parameters for Efficient Sonication and Improved Chromatin Immunoprecipitation of High Molecular Weight Proteins.

by Nikolay A Pchelintsev, Peter D Adams, David M Nelson
Published 2016-01-01

Cytoplasmic chromatin fragments—from mechanisms to therapeutic potential

by Karl N Miller, Nirmalya Dasgupta, Tianhui Liu, Peter D Adams, Maria Grazia Vizioli
Published 2021-01-01

Placing the HIRA Histone Chaperone Complex in the Chromatin Landscape

by Nikolay A. Pchelintsev, Tony McBryan, Taranjit Singh Rai, John van Tuyn, Dominique Ray-Gallet, Geneviève Almouzni, Peter D. Adams
Published 2013-04-01

HIRA, a DiGeorge Syndrome Candidate Gene, Confers Proper Chromatin Accessibility on HSCs and Supports All Stages of Hematopoiesis

by Chao Chen, Ming-an Sun, Claude Warzecha, Mahesh Bachu, Anup Dey, Tiyun Wu, Peter D Adams, Todd Macfarlan, Paul Love, Keiko Ozato
Published 2020-02-01

Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila

by Maria Clara Guida, Ryan Tyge Birse, Alessandra Dall’Agnese, Paula Coutinho Toto, Soda Balla Diop, Antonello Mai, Peter D. Adams, Pier Lorenzo Puri, Rolf Bodmer
Published 2019-01-01

DNMT3B Oncogenic Activity in Human Intestinal Cancer Is Not Linked to CIMP or BRAFV600E Mutation

by Douglas J. MacKenzie, Neil A. Robertson, Iqbal Rather, Claire Reid, Gintare Sendzikaite, Hazel Cruickshanks, Tony McBryan, Andrew Hodges, Catrin Pritchard, Karen Blyth, Peter D. Adams
Published 2020-02-01

Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment

by Tina Wang, Brian Tsui, Jason F. Kreisberg, Neil A. Robertson, Andrew M. Gross, Michael Ku Yu, Hannah Carter, Holly M. Brown-Borg, Peter D. Adams, Trey Ideker
Published 2017-03-01

The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection.

by Steven McFarlane, Anne Orr, Ashley P E Roberts, Kristen L Conn, Victor Iliev, Colin Loney, Ana da Silva Filipe, Katherine Smollett, Quan Gu, Neil Robertson, Peter D Adams, Taranjit Singh Rai, Chris Boutell
Published 2019-03-01

Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions

by John J. Cole, Neil A. Robertson, Mohammed Iqbal Rather, John P. Thomson, Tony McBryan, Duncan Sproul, Tina Wang, Claire Brock, William Clark, Trey Ideker, Richard R. Meehan, Richard A. Miller, Holly M. Brown-Borg, Peter D. Adams
Published 2017-03-01

PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer

by Tânia D. F. Costa, Ting Zhuang, Julie Lorent, Emilia Turco, Helene Olofsson, Miriam Masia-Balague, Miao Zhao, Parisa Rabieifar, Neil Robertson, Raoul Kuiper, Jonas Sjölund, Matthias Spiess, Pablo Hernández-Varas, Uta Rabenhorst, Pernilla Roswall, Ran Ma, Xiaowei Gong, Johan Hartman, Kristian Pietras, Peter D. Adams, Paola Defilippi, Staffan Strömblad
Published 2019-08-01

DNA methylation aging clocks: challenges and recommendations

by Christopher G. Bell, Robert Lowe, Peter D. Adams, Andrea A. Baccarelli, Stephan Beck, Jordana T. Bell, Brock C. Christensen, Vadim N. Gladyshev, Bastiaan T. Heijmans, Steve Horvath, Trey Ideker, Jean-Pierre J. Issa, Karl T. Kelsey, Riccardo E. Marioni, Wolf Reik, Caroline L. Relton, Leonard C. Schalkwyk, Andrew E. Teschendorff, Wolfgang Wagner, Kang Zhang, Vardhman K. Rakyan
Published 2019-11-01

Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest

by Dina Dikovskaya, John J. Cole, Susan M. Mason, Colin Nixon, Saadia A. Karim, Lynn McGarry, William Clark, Rachael N. Hewitt, Morgan A. Sammons, Jiajun Zhu, Dimitris Athineos, Joshua D.G. Leach, Francesco Marchesi, John van Tuyn, Stephen W. Tait, Claire Brock, Jennifer P. Morton, Hong Wu, Shelley L. Berger, Karen Blyth, Peter D. Adams
Published 2015-09-01

BRD4-mediated repression of p53 is a target for combination therapy in AML

by Anne-Louise Latif, Ashley Newcombe, Sha Li, Kathryn Gilroy, Neil A. Robertson, Xue Lei, Helen J. S. Stewart, John Cole, Maria Terradas Terradas, Loveena Rishi, Lynn McGarry, Claire McKeeve, Claire Reid, William Clark, Joana Campos, Kristina Kirschner, Andrew Davis, Jonathan Lopez, Jun-ichi Sakamaki, Jennifer P. Morton, Kevin M. Ryan, Stephen W. G. Tait, Sheela A. Abraham, Tessa Holyoake, Brian Higgins, Xu Huang, Karen Blyth, Mhairi Copland, Timothy J. T. Chevassut, Karen Keeshan, Peter D. Adams
Published 2021-01-01