Identifying collateral and synthetic lethal vulnerabilities within the DNA-damage response

by Pietro Pinoli, Sriganesh Srihari, Limsoon Wong, Stefano Ceri
Published 2021-05-01

Proteome‐wide analysis of T‐cell response to BK polyomavirus in healthy virus carriers and kidney transplant recipients reveals a unique transcriptional and functional profile

by George R Ambalathingal, Ross S Francis, Dillon Corvino, Sriganesh Srihari, Blake T Aftab, Corey Smith, Rajiv Khanna
Published 2020-01-01

Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer

by Murugan Kalimutho, Debottam Sinha, Deepak Mittal, Sriganesh Srihari, Devathri Nanayakkara, Shagufta Shafique, Prahlad Raninga, Purba Nag, Kate Parsons, Kum Kum Khanna
Published 2019-02-01

Targeting BRF2 in Cancer Using Repurposed Drugs

by Behnam Rashidieh, Maryam Molakarimi, Ammar Mohseni, Simon Manuel Tria, Hein Truong, Sriganesh Srihari, Rachael C. Adams, Mathew Jones, Pascal H. G. Duijf, Murugan Kalimutho, Kum Kum Khanna
Published 2021-07-01

'Off-the-shelf’ allogeneic antigen-specific adoptive T-cell therapy for the treatment of multiple EBV-associated malignancies

by Debottam Sinha, Sriganesh Srihari, Kirrliee Beckett, Laetitia Le Texier, Matthew Solomon, Archana Panikkar, George R Ambalathingal, Lea Lekieffre, Pauline Crooks, Sweera Rehan, Michelle A. Neller, Corey Smith, Rajiv Khanna
Published 2021-02-01

Rapid detection of SARS‐CoV‐2‐specific memory T‐cell immunity in recovered COVID‐19 cases

by Katie E Lineburg, Sriganesh Srihari, Mohammed Altaf, Srividhya Swaminathan, Archana Panikkar, Jyothy Raju, Pauline Crooks, George R Ambalathingal, Jose Paulo Martins, Katherine K Matthews, Michelle A Neller, Rajiv Khanna, Corey Smith
Published 2020-01-01

Rapid whole‐blood assay to detect SARS‐CoV‐2‐specific memory T‐cell immunity following a single dose of AstraZeneca ChAdOx1‐S COVID‐19 vaccine

by Katie E Lineburg, Michelle A Neller, George R Ambalathingal, Laetitia Le Texier, Jyothy Raju, Srividhya Swaminathan, Lea Lekieffre, Caitlyn Smith, Sweera Rehan, Pauline Crooks, Archana Panikkar, Sriganesh Srihari, Rajiv Khanna, Corey Smith
Published 2021-01-01

CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer

by Murugan Kalimutho, Debottam Sinha, Jessie Jeffery, Katia Nones, Sriganesh Srihari, Winnie C Fernando, Pascal HG Duijf, Claire Vennin, Prahlad Raninga, Devathri Nanayakkara, Deepak Mittal, Jodi M Saunus, Sunil R Lakhani, J Alejandro López, Kevin J Spring, Paul Timpson, Brian Gabrielli, Nicola Waddell, Kum Kum Khanna
Published 2018-09-01

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D

by Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Published 2020-01-01