An siRNA screen of membrane trafficking genes highlights pathways common to HIV-1 and M-PMV virus assembly and release.

by Xiaoyun Wen, Lingmei Ding, Eric Hunter, Paul Spearman
Published 2014-01-01

CAML does not modulate tetherin-mediated restriction of HIV-1 particle release.

by Mohammed S Ali, Jason Hammonds, Lingmei Ding, Paul Spearman
Published 2010-02-01

Immunoelectron microscopic evidence for Tetherin/BST2 as the physical bridge between HIV-1 virions and the plasma membrane.

by Jason Hammonds, Jaang-Jiun Wang, Hong Yi, Paul Spearman
Published 2010-02-01

Comparative analysis of human microglial models for studies of HIV replication and pathogenesis

by Mohammad A. Rai, Jason Hammonds, Mario Pujato, Christopher Mayhew, Krishna Roskin, Paul Spearman
Published 2020-11-01

A Mason-Pfizer Monkey virus Gag-GFP fusion vector allows visualization of capsid transport in live cells and demonstrates a role for microtubules.

by Jasmine Clark, Petra Grznarova, Elizabeth Stansell, William Diehl, Jan Lipov, Paul Spearman, Tomas Ruml, Eric Hunter
Published 2013-01-01

The intracellular virus-containing compartments in primary human macrophages are largely inaccessible to antibodies and small molecules.

by Hin Chu, Jaang-Jiun Wang, Mingli Qi, Jeong-Joong Yoon, Xiaoyun Wen, Xuemin Chen, Lingmei Ding, Paul Spearman
Published 2012-01-01

Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1.

by Jason E Hammonds, Neal Beeman, Lingmei Ding, Sarah Takushi, Ashwanth C Francis, Jaang-Jiun Wang, Gregory B Melikyan, Paul Spearman
Published 2017-01-01

Challenges and solutions for instituting an efficient maintenance program for laboratory equipment in Central Asian, and developing world, countries

by Riza Ikranbegiin, George Schmid, David Hoos, Andrew Young, Phyllis Della-Latta, Paul Spearman, Artur Ramos, Bereket Alemayehu, Begaiym Achmetova, Gulzhan Nauryzova, Adilya Albetkova
Published 2019-05-01

HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and are Commonly Detected in Plasma from HIV-infected Humans

by Katherine L. Williams, Valerie Cortez, Adam S. Dingens, Johannes S. Gach, Stephanie Rainwater, Julie F. Weis, Xuemin Chen, Paul Spearman, Donald N. Forthal, Julie Overbaugh
Published 2015-10-01

Rab11-FIP1C and Rab14 direct plasma membrane sorting and particle incorporation of the HIV-1 envelope glycoprotein complex.

by Mingli Qi, Janice A Williams, Hin Chu, Xuemin Chen, Jaang-Jiun Wang, Lingmei Ding, Ehiole Akhirome, Xiaoyun Wen, Lynne A Lapierre, James R Goldenring, Paul Spearman
Published 2013-01-01

Different pattern of immunoglobulin gene usage by HIV-1 compared to non-HIV-1 antibodies derived from the same infected subject.

by Liuzhe Li, Xiao-Hong Wang, Sagarika Banerjee, Barbara Volsky, Constance Williams, Diana Virland, Arthur Nadas, Michael S Seaman, Xuemin Chen, Paul Spearman, Susan Zolla-Pazner, Miroslaw K Gorny
Published 2012-01-01

Parainfluenza Virus 5 Priming Followed by SIV/HIV Virus-Like-Particle Boosting Induces Potent and Durable Immune Responses in Nonhuman Primates

by Peng Xiao, Krista Dienger-Stambaugh, Xuemin Chen, Huiling Wei, Shannon Phan, Ashley C. Beavis, Karnail Singh, Nihar R. Deb Adhikary, Pooja Tiwari, Francois Villinger, Biao He, Paul Spearman
Published 2021-02-01

Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein.

by Mark D Hicar, Xuemin Chen, Chidananda Sulli, Trevor Barnes, Jason Goodman, Hakimuddin Sojar, Bryan Briney, Jordan Willis, Valentine U Chukwuma, Spyros A Kalams, Benjamin J Doranz, Paul Spearman, James E Crowe
Published 2016-01-01

Microscale Generation of Cardiospheres Promotes Robust Enrichment of Cardiomyocytes Derived from Human Pluripotent Stem Cells

by Doan C. Nguyen, Tracy A. Hookway, Qingling Wu, Rajneesh Jha, Marcela K. Preininger, Xuemin Chen, Charles A. Easley, Paul Spearman, Shriprasad R. Deshpande, Kevin Maher, Mary B. Wagner, Todd C. McDevitt, Chunhui Xu
Published 2014-08-01

A polyvalent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques

by Sujin Lee, Minh Trang Nguyen, Michael G. Currier, Joe B. Jenkins, Elizabeth A. Strobert, Adriana E. Kajon, Ranjna Madan-Lala, Yury A. Bochkov, James E. Gern, Krishnendu Roy, Xiaoyan Lu, Dean D. Erdman, Paul Spearman, Martin L. Moore
Published 2016-09-01

DNA vaccine priming for seasonal influenza vaccine in children and adolescents 6 to 17 years of age: A phase 1 randomized clinical trial.

by Katherine V Houser, Galina V Yamshchikov, Abbie R Bellamy, Jeanine May, Mary E Enama, Uzma Sarwar, Brenda Larkin, Robert T Bailer, Richard Koup, Myeisha Paskel, Kanta Subbarao, Edwin Anderson, David I Bernstein, Buddy Creech, Harry Keyserling, Paul Spearman, Peter F Wright, Barney S Graham, Julie E Ledgerwood, VRC 702 study team
Published 2018-01-01

EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression.

by Michael G Currier, Sujin Lee, Christopher C Stobart, Anne L Hotard, Remi Villenave, Jia Meng, Carla D Pretto, Michael D Shields, Minh Trang Nguyen, Sean O Todd, Michael H Chi, Jason Hammonds, Stefanie A Krumm, Paul Spearman, Richard K Plemper, Kaori Sakamoto, R Stokes Peebles, Ultan F Power, Martin L Moore
Published 2016-05-01

Seroprevalence of SARS-CoV-2 infection in Cincinnati Ohio USA from August to December 2020.

by Greg Davis, Allen J York, Willis Clark Bacon, Suh-Chin Lin, Monica Malone McNeal, Alexander E Yarawsky, Joseph J Maciag, Jeanette L C Miller, Kathryn C S Locker, Michelle Bailey, Rebecca Stone, Michael Hall, Judith Gonzalez, Alyssa Sproles, E Steve Woodle, Kristen Safier, Kristine A Justus, Paul Spearman, Russell E Ware, Jose A Cancelas, Michael B Jordan, Andrew B Herr, David A Hildeman, Jeffery D Molkentin
Published 2021-01-01

Meta-analysis of HIV-1 vaccine elicited mucosal antibodies in humans

by Kelly E. Seaton, Aaron Deal, Xue Han, Shuying S. Li, Ashley Clayton, Jack Heptinstall, Ann Duerr, Mary A. Allen, Xiaoying Shen, Sheetal Sawant, Nicole L. Yates, Paul Spearman, Gavin Churchyard, Paul A. Goepfert, Janine Maenza, Glenda Gray, Giuseppe Pantaleo, Laura Polakowski, Harriet L. Robinson, Shannon Grant, April K. Randhawa, Ying Huang, Cecilia Morgan, Nicole Grunenberg, Shelly Karuna, Peter B. Gilbert, M. Juliana McElrath, Yunda Huang, Georgia D. Tomaras, NIAID HIV Vaccine Trials Network (HVTN) 076, 088, 086, 096, 097, 205 Study Teams
Published 2021-04-01