PCSK9 and the Gut-Liver-Brain Axis: A Novel Therapeutic Target for Immune Regulation in Alcohol Use Disorder

by Ji Soo Lee, Emma M. O’Connell, Pal Pacher, Falk W. Lohoff
Published 2021-04-01

Restoration of altered microRNA expression in the ischemic heart with resveratrol.

by Partha Mukhopadhyay, Subhendu Mukherjee, Kaimul Ahsan, Angshuman Bagchi, Pal Pacher, Dipak K Das
Published 2010-12-01

Correction: Peroxynitrite Is a Key Mediator of the Cardioprotection Afforded by Ischemic Postconditioning In Vivo

by Jianhui Li, Noureddine Loukili, Nathalie Rosenblatt-Velin, Pal Pacher, François Feihl, Bernard Waeber, Lucas Liaudet
Published 2013-01-01

Peroxynitrite is a key mediator of the cardioprotection afforded by ischemic postconditioning in vivo.

by Jianhui Li, Noureddine Loukili, Nathalie Rosenblatt-Velin, Pal Pacher, François Feihl, Bernard Waeber, Lucas Liaudet
Published 2013-01-01

Correction: Peroxynitrite Is a Key Mediator of the Cardioprotection Afforded by Ischemic Postconditioning In Vivo.

by Jianhui Li, Noureddine Loukili, Nathalie Rosenblatt-Velin, Pal Pacher, François Feihl, Bernard Waeber, Lucas Liaudet
Published 2013-01-01

Correction: Trastuzumab Alters the Expression of Genes Essential for Cardiac Function and Induces Ultrastructural Changes of Cardiomyocytes in Mice

by M. Khair ElZarrad, Partha Mukhopadhyay, Nishant Mohan, Enkui Hao, Milos Dokmanovic, Dianne S. Hirsch, Yi Shen, Pal Pacher, Wen Jin Wu
Published 2014-01-01

Critical Role of TFEB-Mediated Lysosomal Biogenesis in Alcohol-Induced Pancreatitis in Mice and HumansSummary

by Shaogui Wang, Hong-Min Ni, Xiaojuan Chao, Xiaowen Ma, Thomas Kolodecik, Robert De Lisle, Andrew Ballabio, Pal Pacher, Wen-Xing Ding
Published 2020-01-01

Trastuzumab alters the expression of genes essential for cardiac function and induces ultrastructural changes of cardiomyocytes in mice.

by M Khair ElZarrad, Partha Mukhopadhyay, Nishant Mohan, Enkui Hao, Milos Dokmanovic, Dianne S Hirsch, Yi Shen, Pal Pacher, Wen Jin Wu
Published 2013-01-01

Correction: Trastuzumab Alters the Expression of Genes Essential for Cardiac Function and Induces Ultrastructural Changes of Cardiomyocytes in Mice.

by M. Khair ElZarrad, Partha Mukhopadhyay, Nishant Mohan, Enkui Hao, Milos Dokmanovic, Dianne S. Hirsch, Yi Shen, Pal Pacher, Wen Jin Wu
Published 2014-01-01

Bacterial flagellin triggers cardiac innate immune responses and acute contractile dysfunction.

by Joelle Rolli, Nathalie Rosenblatt-Velin, Jianhui Li, Noureddine Loukili, Sandra Levrand, Pal Pacher, Bernard Waeber, François Feihl, Patrick Ruchat, Lucas Liaudet
Published 2010-01-01

CB2 cannabinoid receptors contribute to bacterial invasion and mortality in polymicrobial sepsis.

by Balázs Csóka, Zoltán H Németh, Partha Mukhopadhyay, Zoltán Spolarics, Mohanraj Rajesh, Stephanie Federici, Edwin A Deitch, Sándor Bátkai, Pál Pacher, György Haskó
Published 2009-07-01

Cannabidiol Limits T Cell-Mediated Chronic Autoimmune Myocarditis: Implications to Autoimmune Disorders and Organ Transplantation

by Wen-Shin Lee, Katalin Erdelyi, Csaba Matyas, Partha Mukhopadhyay, Zoltan V Varga, Lucas Liaudet, György Haskó, Daniela Čiháková, Raphael Mechoulam, Pal Pacher
Published 2016-01-01

Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells.

by Christoph W Michalski, Milena Maier, Mert Erkan, Danguole Sauliunaite, Frank Bergmann, Pal Pacher, Sandor Batkai, Nathalia A Giese, Thomas Giese, Helmut Friess, Jörg Kleeff
Published 2008-02-01

Role of endocannabinoids and cannabinoid-1 receptors in cerebrocortical blood flow regulation.

by András Iring, Éva Ruisanchez, Miriam Leszl-Ishiguro, Béla Horváth, Rita Benkő, Zsombor Lacza, Zoltán Járai, Péter Sándor, Vincenzo Di Marzo, Pál Pacher, Zoltán Benyó
Published 2013-01-01

Endogenous cannabinoid receptor CB1 activation promotes vascular smooth-muscle cell proliferation and neointima formation

by Filippo Molica, Fabienne Burger, Aurélien Thomas, Christian Staub, Anne Tailleux, Bart Staels, Graziano Pelli, Andreas Zimmer, Benjamin Cravatt, Christian M. Matter, Pal Pacher, Sabine Steffens
Published 2013-05-01

Neutrophil–Hepatic Stellate Cell Interactions Promote Fibrosis in Experimental Steatohepatitis

by Zhou Zhou, Ming-Jiang Xu, Yan Cai, Wei Wang, Joy X. Jiang, Zoltan V. Varga, Dechun Feng, Pal Pacher, George Kunos, Natalie J. Torok, Bin Gao
Published 2018-01-01

Oxidative/Nitrative Stress and Inflammation Drive Progression of Doxorubicin-Induced Renal Fibrosis in Rats as Revealed by Comparing a Normal and a Fibrosis-Resistant Rat Strain.

by Csaba Imre Szalay, Katalin Erdélyi, Gábor Kökény, Enikő Lajtár, Mária Godó, Csaba Révész, Tamás Kaucsár, Norbert Kiss, Márta Sárközy, Tamás Csont, Tibor Krenács, Gábor Szénási, Pál Pacher, Péter Hamar
Published 2015-01-01

Alcohol Binge-Induced Cardiovascular Dysfunction Involves Endocannabinoid–CB1-R Signaling

by Janos Paloczi, PhD, Csaba Matyas, MD, PhD, Resat Cinar, PhD, Zoltan V. Varga, MD, PhD, György Hasko, MD, PhD, Thomas H. Schindler, MD, George Kunos, MD, PhD, Pal Pacher, MD, PhD
Published 2019-09-01

Alternative Splicing of NOX4 in the Failing Human Heart

by Zoltán V. Varga, Zoltán V. Varga, Márton Pipicz, Júlia A. Baán, Tamás Baranyai, Gábor Koncsos, Przemyslaw Leszek, Mariusz Kuśmierczyk, Fátima Sánchez-Cabo, Pablo García-Pavía, Gábor J. Brenner, Zoltán Giricz, Zoltán Giricz, Tamás Csont, Luca Mendler, Luca Mendler, Enrique Lara-Pezzi, Pál Pacher, Péter Ferdinandy, Péter Ferdinandy, Péter Ferdinandy
Published 2017-11-01

Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity

by Marjolein Soethoudt, Uwe Grether, Jürgen Fingerle, Travis W. Grim, Filomena Fezza, Luciano de Petrocellis, Christoph Ullmer, Benno Rothenhäusler, Camille Perret, Noortje van Gils, David Finlay, Christa MacDonald, Andrea Chicca, Marianela Dalghi Gens, Jordyn Stuart, Henk de Vries, Nicolina Mastrangelo, Lizi Xia, Georgios Alachouzos, Marc P. Baggelaar, Andrea Martella, Elliot D. Mock, Hui Deng, Laura H. Heitman, Mark Connor, Vincenzo Di Marzo, Jürg Gertsch, Aron H. Lichtman, Mauro Maccarrone, Pal Pacher, Michelle Glass, Mario van der Stelt
Published 2017-01-01