Isothiocyanates and Glucosinolates from Sisymbrium officinale (L.) Scop. (“the Singers’ Plant”): Isolation and in Vitro Assays on the Somatosensory and Pain Receptor TRPA1 Channel...

by Gigliola Borgonovo, Nathan Zimbaldi, Marta Guarise, Patrizia De Nisi, Luciano De Petrocellis, Aniello Schiano Moriello, Angela Bassoli
Published 2019-03-01

Moringin, A Stable Isothiocyanate from <i>Moringa oleifera</i>, Activates the Somatosensory and Pain Receptor TRPA1 Channel In Vitro

by Gigliola Borgonovo, Luciano De Petrocellis, Aniello Schiano Moriello, Simona Bertoli, Alessandro Leone, Alberto Battezzati, Stefania Mazzini, Angela Bassoli
Published 2020-02-01

The Combined Effect of Branching and Elongation on the Bioactivity Profile of Phytocannabinoids. Part I: Thermo-TRPs

by Daiana Mattoteia, Aniello Schiano Moriello, Orazio Taglialatela-Scafati, Pietro Amodeo, Luciano De Petrocellis, Giovanni Appendino, Rosa Maria Vitale, Diego Caprioglio
Published 2021-08-01

Identification and Characterization of Cannabimovone, a Cannabinoid from <i>Cannabis sativa</i>, as a Novel PPARγ Agonist via a Combined Computational and Functional Study

by Fabio Arturo Iannotti, Fabrizia De Maio, Elisabetta Panza, Giovanni Appendino, Orazio Taglialatela-Scafati, Luciano De Petrocellis, Pietro Amodeo, Rosa Maria Vitale
Published 2020-03-01

Leucettamols, Bifunctionalized Marine Sphingoids, Act as Modulators of TRPA1 and TRPM8 Channels

by Orazio Taglialatela-Scafati, Vincenzo Di Marzo, Aniello Schiano Moriello, Luciano De Petrocellis, Giorgio Bavestrello, Barbara Calcinai, Masteria Yunovilsa Putra, Ernesto Fattorusso, Giuseppina Chianese
Published 2012-11-01

A Glucuronic Acid-Palmitoylethanolamide Conjugate (GLUPEA) Is an Innovative Drug Delivery System and a Potential Bioregulator

by Emiliano Manzo, Aniello Schiano Moriello, Francesco Tinto, Roberta Verde, Marco Allarà, Luciano De Petrocellis, Ester Pagano, Angelo A. Izzo, Vincenzo Di Marzo, Stefania Petrosino
Published 2021-02-01

Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism.

by Katarzyna Starowicz, Wioletta Makuch, Michal Korostynski, Natalia Malek, Michal Slezak, Magdalena Zychowska, Stefania Petrosino, Luciano De Petrocellis, Luigia Cristino, Barbara Przewlocka, Vincenzo Di Marzo
Published 2013-01-01

Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes

by Sarah Mazzotta, Gabriele Carullo, Aniello Schiano Moriello, Pietro Amodeo, Vincenzo Di Marzo, Margarita Vega-Holm, Rosa Maria Vitale, Francesca Aiello, Antonella Brizzi, Luciano De Petrocellis
Published 2020-10-01

TRPA1 Modulating C14 Polyacetylenes from the Iranian Endemic Plant Echinophora platyloba

by Giuseppina Chianese, Carmina Sirignano, Yalda Shokoohinia, Zeynab Mohammadi, Leili Bazvandi, Fataneh Jafari, Fereshteh Jalilian, Aniello Schiano Moriello, Luciano De Petrocellis, Orazio Taglialatela-Scafati, Daniela Rigano
Published 2018-07-01

Identification and Characterization of Cannabidiol as an OX1R Antagonist by Computational and In Vitro Functional Validation

by Rosa Maria Vitale, Fabio Arturo Iannotti, Aniello Schiano Moriello, Lea Tunisi, Fabiana Piscitelli, Ranjev Savopoulos, Luigia Cristino, Luciano De Petrocellis, Pietro Amodeo, Roy Gray, Vincenzo Di Marzo
Published 2021-08-01

Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter.

by Alessia Ligresti, Luciano De Petrocellis, Dolores Hernán Pérez de la Ossa, Rosario Aberturas, Luigia Cristino, Aniello Schiano Moriello, Andrea Finizio, M Esther Gil, Ana-Isabel Torres, Jesús Molpeceres, Vincenzo Di Marzo
Published 2010-04-01

Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity

by Marjolein Soethoudt, Uwe Grether, Jürgen Fingerle, Travis W. Grim, Filomena Fezza, Luciano de Petrocellis, Christoph Ullmer, Benno Rothenhäusler, Camille Perret, Noortje van Gils, David Finlay, Christa MacDonald, Andrea Chicca, Marianela Dalghi Gens, Jordyn Stuart, Henk de Vries, Nicolina Mastrangelo, Lizi Xia, Georgios Alachouzos, Marc P. Baggelaar, Andrea Martella, Elliot D. Mock, Hui Deng, Laura H. Heitman, Mark Connor, Vincenzo Di Marzo, Jürg Gertsch, Aron H. Lichtman, Mauro Maccarrone, Pal Pacher, Michelle Glass, Mario van der Stelt
Published 2017-01-01