Peripheral cannabinoid-1 receptor blockade restores hypothalamic leptin signaling

by Joseph Tam, Gergő Szanda, Adi Drori, Ziyi Liu, Resat Cinar, Yoshihiro Kashiwaya, Marc L. Reitman, George Kunos
Published 2017-10-01

Cholesterol as a modulator of cannabinoid receptor CB2 signaling

by Alexei Yeliseev, Malliga R. Iyer, Thomas T. Joseph, Nathan J. Coffey, Resat Cinar, Lioudmila Zoubak, George Kunos, Klaus Gawrisch
Published 2021-02-01

Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization

by Elias Björnson, Bani Mukhopadhyay, Anna Asplund, Nusa Pristovsek, Resat Cinar, Stefano Romeo, Mathias Uhlen, George Kunos, Jens Nielsen, Adil Mardinoglu
Published 2015-12-01

Peripheral Hybrid CB1R and iNOS Antagonist MRI-1867 Displays Anti-Fibrotic Efficacy in Bleomycin-Induced Skin Fibrosis

by Charles N. Zawatsky, Charles N. Zawatsky, Joshua K. Park, Jasmina Abdalla, George Kunos, Malliga R. Iyer, Malliga R. Iyer, Resat Cinar, Resat Cinar
Published 2021-09-01

Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice.

by Jaroslawna Meister, Derek B J Bone, Grzegorz Godlewski, Ziyi Liu, Regina J Lee, Sergey A Vishnivetskiy, Vsevolod V Gurevich, Danielle Springer, George Kunos, Jürgen Wess
Published 2019-10-01

Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysisResearch in context

by Rui Benfeitas, Gholamreza Bidkhori, Bani Mukhopadhyay, Martina Klevstig, Muhammad Arif, Cheng Zhang, Sunjae Lee, Resat Cinar, Jens Nielsen, Mathias Uhlen, Jan Boren, George Kunos, Adil Mardinoglu
Published 2019-02-01

Neutrophil–Hepatic Stellate Cell Interactions Promote Fibrosis in Experimental Steatohepatitis

by Zhou Zhou, Ming-Jiang Xu, Yan Cai, Wei Wang, Joy X. Jiang, Zoltan V. Varga, Dechun Feng, Pal Pacher, George Kunos, Natalie J. Torok, Bin Gao
Published 2018-01-01

The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system.

by Blerina Kola, Imre Farkas, Mirjam Christ-Crain, Gábor Wittmann, Francesca Lolli, Faisal Amin, Judith Harvey-White, Zsolt Liposits, George Kunos, Ashley B Grossman, Csaba Fekete, Márta Korbonits
Published 2008-03-01

Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice

by Tony Jourdan, Sarah M. Nicoloro, Zhou Zhou, Yuefei Shen, Jie Liu, Nathan J. Coffey, Resat Cinar, Grzegorz Godlewski, Bin Gao, Myriam Aouadi, Michael P. Czech, George Kunos
Published 2017-11-01

Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia

by Luis Santos-Molina, Alexa Herrerias, Charles N. Zawatsky, Ozge Gunduz-Cinar, Resat Cinar, Malliga R. Iyer, Casey M. Wood, Yuhong Lin, Bin Gao, George Kunos, Grzegorz Godlewski
Published 2021-08-01

Alcohol Binge-Induced Cardiovascular Dysfunction Involves Endocannabinoid–CB1-R Signaling

by Janos Paloczi, PhD, Csaba Matyas, MD, PhD, Resat Cinar, PhD, Zoltan V. Varga, MD, PhD, György Hasko, MD, PhD, Thomas H. Schindler, MD, George Kunos, MD, PhD, Pal Pacher, MD, PhD
Published 2019-09-01

CB1R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky–Pudlak syndrome

by Resat Cinar, Joshua K. Park, Charles N. Zawatsky, Nathan J. Coffey, Steven P. Bodine, Jasmina Abdalla, Tadafumi Yokoyama, Tony Jourdan, Lindsey Jay, Mei Xing G. Zuo, Kevin J. O'Brien, Junfeng Huang, Ken Mackie, Asaf Alimardanov, Malliga R. Iyer, William A. Gahl, George Kunos, Bernadette R. Gochuico, May Christine V. Malicdan
Published 2021-07-01

Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex

by So Yeon Kim, Jong-Min Jeong, Soo Jin Kim, Wonhyo Seo, Myung-Ho Kim, Won-Mook Choi, Wonbeak Yoo, Jun-Hee Lee, Young-Ri Shim, Hyon-Seung Yi, Young-Sun Lee, Hyuk Soo Eun, Byung Seok Lee, Kwangsik Chun, Suk-Jo Kang, Sun Chang Kim, Bin Gao, George Kunos, Ho Min Kim, Won-Il Jeong
Published 2017-12-01