Integrin Targeted Therapeutics

by Melissa Millard, Srinivas Odde, Nouri Neamati
Published 2011-01-01

Mechanistic evaluation of a novel small molecule targeting mitochondria in pancreatic cancer cells.

by Yumna H Shabaik, Melissa Millard, Nouri Neamati
Published 2013-01-01

Small Molecule Inhibitors of CXCR4

by Bikash Debnath, Shili Xu, Fedora Grande, Antonio Garofalo, Nouri Neamati
Published 2013-01-01

Preclinical evaluation of novel triphenylphosphonium salts with broad-spectrum activity.

by Melissa Millard, Divya Pathania, Yumna Shabaik, Laleh Taheri, Jinxia Deng, Nouri Neamati
Published 2010-01-01

A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication.

by Erik Serrao, Wannes Thys, Jonas Demeulemeester, Laith Q Al-Mawsawi, Frauke Christ, Zeger Debyser, Nouri Neamati
Published 2012-01-01

Tautomeric-Dependent Lactam Cycloaddition with Nitrile Oxide: Facile Synthesis of 1,2,4-Oxadiazole[4,5‑a]indolone Derivatives

by Kun-Ming Jiang, Urarika Luesakul, Shu-Yue Zhao, Kun An, Nongnuj Muangsin, Nouri Neamati, Yi Jin, Jun Lin
Published 2017-07-01

Design and Synthesis of Bis-amide and Hydrazide-containing Derivatives of Malonic Acid as Potential HIV-1 Integrase Inhibitors

by Nouri Neamati, Nicolino Pala, Alessia Cosseddu, Alessandro Dessì, Roberto Dallocchio, Maria Paola Delussu, Ugo Azzena, Mario Sechi
Published 2008-10-01

Design, Synthesis and Structure-activity Studies of Rhodanine Derivatives as HIV-1 Integrase Inhibitors

by Kavya Ramkumar, Vladimir N. Yarovenko, Alexandra S. Nikitina, Igor V. Zavarzin, Mikhail M. Krayushkin, Leonid V. Kovalenko, Adrian Esqueda, Srinivas Odde, Nouri Neamati
Published 2010-06-01

Clinicopathological significance of endoplasmic reticulum stress proteins in ovarian carcinoma

by Soma Samanta, Shuzo Tamura, Louis Dubeau, Paulette Mhawech-Fauceglia, Yohei Miyagi, Hisamori Kato, Rich Lieberman, Ronald J. Buckanovich, Yvonne G. Lin, Nouri Neamati
Published 2020-02-01

Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma.

by Helty Adisetiyo, Mengmeng Liang, Chun-Peng Liao, Ari Aycock-Williams, Michael B Cohen, Shili Xu, Nouri Neamati, Edward M Conway, Chieh-Yang Cheng, Alexander Yu Nikitin, Pradip Roy-Burman
Published 2013-01-01

Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor

by Kavya Ramkumar, Soma Samanta, Anahita Kyani, Suhui Yang, Shuzo Tamura, Elizabeth Ziemke, Jeanne A. Stuckey, Si Li, Krishnapriya Chinnaswamy, Hiroyuki Otake, Bikash Debnath, Vladimir Yarovenko, Judith S. Sebolt-Leopold, Mats Ljungman, Nouri Neamati
Published 2016-10-01

UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer

by Yajing Liu, Sahezeel Awadia, Amy Delaney, Merna Sitto, Carl G. Engelke, Heli Patel, Andrew Calcaterra, Sylvia Zelenka-Wang, Hojin Lee, Joseph Contessa, Nouri Neamati, Mats Ljungman, Theodore S. Lawrence, Meredith A. Morgan, Alnawaz Rehemtulla
Published 2020-11-01

Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation

by Mark M. Hughes, Alexander Hooftman, Stefano Angiari, Padmaja Tummala, Zbigniew Zaslona, Marah C. Runtsch, Anne F. McGettrick, Caroline E. Sutton, Ciana Diskin, Melissa Rooke, Shuhei Takahashi, Srinivasan Sundararaj, Marco G. Casarotto, Jane E. Dahlstrom, Eva M. Palsson-McDermott, Sinead C. Corr, Kingston H.G. Mills, Roger J.S. Preston, Nouri Neamati, Yiyue Xie, Jonathan B. Baell, Philip G. Board, Luke A.J. O’Neill
Published 2019-10-01