Transcriptional Profiling of STAT1 Gain-of-Function Reveals Common and Mutation-Specific Fingerprints

by Simone Giovannozzi, Simone Giovannozzi, Jonas Demeulemeester, Jonas Demeulemeester, Rik Schrijvers, Rik Gijsbers, Rik Gijsbers
Published 2021-02-01

Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras.

by Lenard S Vranckx, Jonas Demeulemeester, Zeger Debyser, Rik Gijsbers
Published 2016-01-01

A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication.

by Erik Serrao, Wannes Thys, Jonas Demeulemeester, Laith Q Al-Mawsawi, Frauke Christ, Zeger Debyser, Nouri Neamati
Published 2012-01-01

BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements

by Sara El Ashkar, Jan De Rijck, Jonas Demeulemeester, Sofie Vets, Paradise Madlala, Katerina Cermakova, Zeger Debyser, Rik Gijsbers
Published 2014-01-01

Inhibitors of the integrase–transportin-SR2 interaction block HIV nuclear import

by Jonas Demeulemeester, Jolien Blokken, Stéphanie De Houwer, Lieve Dirix, Hugo Klaassen, Arnaud Marchand, Patrick Chaltin, Frauke Christ, Zeger Debyser
Published 2018-01-01

Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy

by Sara El Ashkar, Dominique Van Looveren, Franziska Schenk, Lenard S. Vranckx, Jonas Demeulemeester, Jan De Rijck, Zeger Debyser, Ute Modlich, Rik Gijsbers
Published 2017-06-01

Correction: LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs.

by Rik Schrijvers, Jan De Rijck, Jonas Demeulemeester, Noritaka Adachi, Sofie Vets, Keshet Ronen, Frauke Christ, Frederic D Bushman, Zeger Debyser, Rik Gijsbers
Published 2020-09-01

LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs.

by Rik Schrijvers, Jan De Rijck, Jonas Demeulemeester, Noritaka Adachi, Sofie Vets, Keshet Ronen, Frauke Christ, Frederic D Bushman, Zeger Debyser, Rik Gijsbers
Published 2012-01-01

LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV

by Lenard S. Vranckx, Jonas Demeulemeester, Suha Saleh, Annegret Boll, Gerlinde Vansant, Rik Schrijvers, Caroline Weydert, Emilie Battivelli, Eric Verdin, Anna Cereseto, Frauke Christ, Rik Gijsbers, Zeger Debyser
Published 2016-06-01

Correction to: HIV-1 IN/Pol recruits LEDGF/p75 into viral particles

by Belete Ayele Desimmie, Caroline Weydert, Rik Schrijvers, Sofie Vets, Jonas Demeulemeester, Paul Proost, Igor Paron, Jan De Rijck, Jan Mast, Norbert Bannert, Rik Gijsbers, Frauke Christ, Zeger Debyser
Published 2020-07-01

The BET Family of Proteins Targets Moloney Murine Leukemia Virus Integration near Transcription Start Sites

by Jan De Rijck, Christine de Kogel, Jonas Demeulemeester, Sofie Vets, Sara El Ashkar, Nirav Malani, Frederic D. Bushman, Bart Landuyt, Steven J. Husson, Katrien Busschots, Rik Gijsbers, Zeger Debyser
Published 2013-11-01

Correction to: LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions

by Belete Ayele Desimmie, Rik Schrijvers, Jonas Demeulemeester, Doortje Borrenberghs, Caroline Weydert, Wannes Thys, Sofie Vets, Barbara Van Remoortel, Johan Hofkens, Jan De Rijck, Jelle Hendrix, Norbert Bannert, Rik Gijsbers, Frauke Christ, Zeger Debyser
Published 2020-07-01

Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors

by Jiqiu Cheng, Jonas Demeulemeester, David C. Wedge, Hans Kristian M. Vollan, Jason J. Pitt, Hege G. Russnes, Bina P. Pandey, Gro Nilsen, Silje Nord, Graham R. Bignell, Kevin P. White, Anne-Lise Børresen-Dale, Peter J. Campbell, Vessela N. Kristensen, Michael R. Stratton, Ole Christian Lingjærde, Yves Moreau, Peter Van Loo
Published 2019-01-01

Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors

by Jiqiu Cheng, Jonas Demeulemeester, David C. Wedge, Hans Kristian M. Vollan, Jason J. Pitt, Hege G. Russnes, Bina P. Pandey, Gro Nilsen, Silje Nord, Graham R. Bignell, Kevin P. White, Anne-Lise Børresen-Dale, Peter J. Campbell, Vessela N. Kristensen, Michael R. Stratton, Ole Christian Lingjærde, Yves Moreau, Peter Van Loo
Published 2017-10-01

Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors

by Jiqiu Cheng, Jonas Demeulemeester, David C. Wedge, Hans Kristian M. Vollan, Jason J. Pitt, Hege G. Russnes, Bina P. Pandey, Gro Nilsen, Silje Nord, Graham R. Bignell, Kevin P. White, Anne-Lise Børresen-Dale, Peter J. Campbell, Vessela N. Kristensen, Michael R. Stratton, Ole Christian Lingjærde, Yves Moreau, Peter Van Loo
Published 2018-12-01

Recurrent rearrangements of FOS and FOSB define osteoblastoma

by Matthew W. Fittall, William Mifsud, Nischalan Pillay, Hongtao Ye, Anna-Christina Strobl, Annelien Verfaillie, Jonas Demeulemeester, Lei Zhang, Fitim Berisha, Maxime Tarabichi, Matthew D. Young, Elena Miranda, Patrick S. Tarpey, Roberto Tirabosco, Fernanda Amary, Agamemnon E. Grigoriadis, Michael R. Stratton, Peter Van Loo, Cristina R. Antonescu, Peter J. Campbell, Adrienne M. Flanagan, Sam Behjati
Published 2018-06-01