An improved, scalable synthesis of Notum inhibitor LP-922056 using 1-chloro-1,2-benziodoxol-3-one as a superior electrophilic chlorinating agent

by Nicky J. Willis, Elliott D. Bayle, George Papageorgiou, David Steadman, Benjamin N. Atkinson, William Mahy, Paul V. Fish
Published 2019-11-01

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes

by Frederick A. Partridge, Anwen E. Brown, Steven D. Buckingham, Nicky J. Willis, Graham M. Wynne, Ruth Forman, Kathryn J. Else, Alison A. Morrison, Jacqueline B. Matthews, Angela J. Russell, David A. Lomas, David B. Sattelle
Published 2018-04-01

Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo.

by Frederick A Partridge, Emma A Murphy, Nicky J Willis, Carole J R Bataille, Ruth Forman, Narinder Heyer-Chauhan, Bruno Marinič, Daniel J C Sowood, Graham M Wynne, Kathryn J Else, Angela J Russell, David B Sattelle
Published 2017-02-01

2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm.

by Frederick A Partridge, Ruth Forman, Nicky J Willis, Carole J R Bataille, Emma A Murphy, Anwen E Brown, Narinder Heyer-Chauhan, Bruno Marinič, Daniel J C Sowood, Graham M Wynne, Kathryn J Else, Angela J Russell, David B Sattelle
Published 2018-07-01