Caenorhabditis elegans meets microsporidia: the nematode killers from Paris.

by Jonathan Hodgkin, Frederick A Partridge
Published 2008-12-01

Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics

by Steven D. Buckingham, Frederick A. Partridge, David B. Sattelle
Published 2014-12-01

Serotonergic chemosensory neurons modify the C. elegans immune response by regulating G-protein signaling in epithelial cells.

by Alexandra Anderson, Henry Laurenson-Schafer, Frederick A Partridge, Jonathan Hodgkin, Rachel McMullan
Published 2013-01-01

Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance...

by Steven D Buckingham, Frederick A Partridge, Beth C Poulton, Benjamin S Miller, Rachel A McKendry, Gareth J Lycett, David B Sattelle
Published 2021-06-01

Anthelmintic drug discovery: target identification, screening methods and the role of open science

by Frederick A. Partridge, Ruth Forman, Carole J. R. Bataille, Graham M. Wynne, Marina Nick, Angela J. Russell, Kathryn J. Else, David B. Sattelle
Published 2020-06-01

The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease

by Shogo Furutani, Makoto Ihara, Kristin Lees, Steven D. Buckingham, Frederick A. Partridge, Jonathan A. David, Rohit Patel, Scott Warchal, Ian R. Mellor, Kazuhiko Matsuda, David B. Sattelle
Published 2018-08-01

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes

by Frederick A. Partridge, Anwen E. Brown, Steven D. Buckingham, Nicky J. Willis, Graham M. Wynne, Ruth Forman, Kathryn J. Else, Alison A. Morrison, Jacqueline B. Matthews, Angela J. Russell, David A. Lomas, David B. Sattelle
Published 2018-04-01

Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo.

by Frederick A Partridge, Emma A Murphy, Nicky J Willis, Carole J R Bataille, Ruth Forman, Narinder Heyer-Chauhan, Bruno Marinič, Daniel J C Sowood, Graham M Wynne, Kathryn J Else, Angela J Russell, David B Sattelle
Published 2017-02-01

2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm.

by Frederick A Partridge, Ruth Forman, Nicky J Willis, Carole J R Bataille, Emma A Murphy, Anwen E Brown, Narinder Heyer-Chauhan, Bruno Marinič, Daniel J C Sowood, Graham M Wynne, Kathryn J Else, Angela J Russell, David B Sattelle
Published 2018-07-01