In silico design of a T-cell epitope vaccine candidate for parasitic helminth infection.

by Ayat Zawawi, Ruth Forman, Hannah Smith, Iris Mair, Murtala Jibril, Munirah H Albaqshi, Andrew Brass, Jeremy P Derrick, Kathryn J Else
Published 2020-03-01

Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages.

by Ruth Forman, Larisa Logunova, Hannah Smith, Kelly Wemyss, Iris Mair, Louis Boon, Judith E Allen, Werner Muller, Joanne L Pennock, Kathryn J Else
Published 2021-07-01

Anthelmintic drug discovery: target identification, screening methods and the role of open science

by Frederick A. Partridge, Ruth Forman, Carole J. R. Bataille, Graham M. Wynne, Marina Nick, Angela J. Russell, Kathryn J. Else, David B. Sattelle
Published 2020-06-01

IFNγ signaling endows DCs with the capacity to control type I inflammation during parasitic infection through promoting T-bet+ regulatory T cells.

by Hyang-Mi Lee, Anne Fleige, Ruth Forman, Sunglim Cho, Aly Azeem Khan, Ling-Li Lin, Duc T Nguyen, Aisling O'Hara-Hall, Zhinan Yin, Christopher A Hunter, Werner Muller, Li-Fan Lu
Published 2015-02-01

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes

by Frederick A. Partridge, Anwen E. Brown, Steven D. Buckingham, Nicky J. Willis, Graham M. Wynne, Ruth Forman, Kathryn J. Else, Alison A. Morrison, Jacqueline B. Matthews, Angela J. Russell, David A. Lomas, David B. Sattelle
Published 2018-04-01

Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo.

by Frederick A Partridge, Emma A Murphy, Nicky J Willis, Carole J R Bataille, Ruth Forman, Narinder Heyer-Chauhan, Bruno Marinič, Daniel J C Sowood, Graham M Wynne, Kathryn J Else, Angela J Russell, David B Sattelle
Published 2017-02-01

2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm.

by Frederick A Partridge, Ruth Forman, Nicky J Willis, Carole J R Bataille, Emma A Murphy, Anwen E Brown, Narinder Heyer-Chauhan, Bruno Marinič, Daniel J C Sowood, Graham M Wynne, Kathryn J Else, Angela J Russell, David B Sattelle
Published 2018-07-01