Structural basis of human PCNA sliding on DNA

by Matteo De March, Nekane Merino, Susana Barrera-Vilarmau, Ramon Crehuet, Silvia Onesti, Francisco J. Blanco, Alfredo De Biasio
Published 2017-01-01

The metastasis suppressor KISS1 is an intrinsically disordered protein slightly more extended than a random coil.

by Alain Ibáñez de Opakua, Nekane Merino, Maider Villate, Tiago N Cordeiro, Georgina Ormaza, Marta Sánchez-Carbayo, Tammo Diercks, Pau Bernadó, Francisco J Blanco
Published 2017-01-01

The Gαi-GIV binding interface is a druggable protein-protein interaction

by Vincent DiGiacomo, Alain Ibáñez de Opakua, Maria P. Papakonstantinou, Lien T. Nguyen, Nekane Merino, Juan B. Blanco-Canosa, Francisco J. Blanco, Mikel Garcia-Marcos
Published 2017-08-01

Structure of the processive human Pol δ holoenzyme

by Claudia Lancey, Muhammad Tehseen, Vlad-Stefan Raducanu, Fahad Rashid, Nekane Merino, Timothy J. Ragan, Christos G. Savva, Manal S. Zaher, Afnan Shirbini, Francisco J. Blanco, Samir M. Hamdan, Alfredo De Biasio
Published 2020-02-01

Proliferating cell nuclear antigen (PCNA) interactions in solution studied by NMR.

by Alfredo De Biasio, Ramón Campos-Olivas, Ricardo Sánchez, Jorge P López-Alonso, David Pantoja-Uceda, Nekane Merino, Maider Villate, Jose M Martin-Garcia, Francisco Castillo, Irene Luque, Francisco J Blanco
Published 2012-01-01

Carcinoembryonic Antigen (CEA)-Specific 4-1BB-Costimulation Induced by CEA-Targeted 4-1BB-Agonistic Trimerbodies

by Kasper Mikkelsen, Seandean Lykke Harwood, Marta Compte, Nekane Merino, Kasper Mølgaard, Simon Lykkemark, Ana Alvarez-Mendez, Francisco J. Blanco, Francisco J. Blanco, Luis Álvarez-Vallina, Luis Álvarez-Vallina, Luis Álvarez-Vallina
Published 2019-07-01

Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif

by Alain Ibáñez de Opakua, Kshitij Parag-Sharma, Vincent DiGiacomo, Nekane Merino, Anthony Leyme, Arthur Marivin, Maider Villate, Lien T. Nguyen, Miguel Angel de la Cruz-Morcillo, Juan B. Blanco-Canosa, Sekar Ramachandran, George S. Baillie, Richard A. Cerione, Francisco J. Blanco, Mikel Garcia-Marcos
Published 2017-05-01

ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy

by Seandean Lykke Harwood, Ana Alvarez-Cienfuegos, Natalia Nuñez-Prado, Marta Compte, Sara Hernández-Pérez, Nekane Merino, Jaume Bonet, Rocio Navarro, Paul M. P. Van Bergen en Henegouwen, Simon Lykkemark, Kasper Mikkelsen, Kasper Mølgaard, Frederic Jabs, Laura Sanz, Francisco J. Blanco, Pedro Roda-Navarro, Luis Alvarez-Vallina
Published 2018-01-01

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity

by Marta Compte, Seandean Lykke Harwood, Ines G. Muñoz, Rocio Navarro, Manuela Zonca, Gema Perez-Chacon, Ainhoa Erce-Llamazares, Nekane Merino, Antonio Tapia-Galisteo, Angel M. Cuesta, Kasper Mikkelsen, Eduardo Caleiras, Natalia Nuñez-Prado, M. Angela Aznar, Simon Lykkemark, Jorge Martínez-Torrecuadrada, Ignacio Melero, Francisco J. Blanco, Jorge Bernardino de la Serna, Juan M. Zapata, Laura Sanz, Luis Alvarez-Vallina
Published 2018-11-01