Development of a human immuno-oncology therapeutic agent targeting HER2: targeted delivery of granzyme B

by Lawrence H. Cheung, Yunli Zhao, Ana Alvarez-Cienfuegos, Khalid A. Mohamedali, Yu J. Cao, Walter N. Hittelman, Michael G. Rosenblum
Published 2019-07-01

The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype.

by Patricia Santos-Valle, Irene Guijarro-Muñoz, Angel M Cuesta, Vanesa Alonso-Camino, Maider Villate, Ana Alvarez-Cienfuegos, Francisco J Blanco, Laura Sanz, Luis Alvarez-Vallina
Published 2012-01-01

Basement membrane-rich organoids with functional human blood vessels are permissive niches for human breast cancer metastasis.

by Rodrigo Fernández-Periáñez, Irene Molina-Privado, Federico Rojo, Irene Guijarro-Muñoz, Vanesa Alonso-Camino, Sandra Zazo, Marta Compte, Ana Alvarez-Cienfuegos, Angel M Cuesta, David Sánchez-Martín, Ana M Alvarez-Méndez, Laura Sanz, Luis Alvarez-Vallina
Published 2013-01-01

ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy

by Seandean Lykke Harwood, Ana Alvarez-Cienfuegos, Natalia Nuñez-Prado, Marta Compte, Sara Hernández-Pérez, Nekane Merino, Jaume Bonet, Rocio Navarro, Paul M. P. Van Bergen en Henegouwen, Simon Lykkemark, Kasper Mikkelsen, Kasper Mølgaard, Frederic Jabs, Laura Sanz, Francisco J. Blanco, Pedro Roda-Navarro, Luis Alvarez-Vallina
Published 2018-01-01