Direct quantitative determination of ceramide glycosylation in vivo: a new approach to evaluate cellular enzyme activity of glucosylceramide synthase

by Vineet Gupta, Gauri A. Patwardhan, Qian-Jin Zhang, Myles C. Cabot, S. Michal Jazwinski, Yong-Yu Liu
Published 2010-04-01

Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells

by Yong-Yu Liu, Tie Yan Han, Jing Yuan Yu, Arie Bitterman, Ahn Le, Armando E. Giuliano, Myles C. Cabot
Published 2004-05-01

A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis.

by Gauri A Patwardhan, Qian-Jin Zhang, Dongmei Yin, Vineet Gupta, Jianxiong Bao, Can E Senkal, Besim Ogretmen, Myles C Cabot, Girish V Shah, Paul W Sylvester, S Michal Jazwinski, Yong-Yu Liu
Published 2009-09-01

Intrinsic OXPHOS limitations underlie cellular bioenergetics in leukemia

by Margaret AM Nelson, Kelsey L McLaughlin, James T Hagen, Hannah S Coalson, Cameron Schmidt, Miki Kassai, Kimberly A Kew, Joseph M McClung, P Darrell Neufer, Patricia Brophy, Nasreen A Vohra, Darla Liles, Myles C Cabot, Kelsey H Fisher-Wellman
Published 2021-06-01

Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation

by Su-Fern Tan, Wendy Dunton, Xin Liu, Todd E. Fox, Samy A.F. Morad, Dhimant Desai, Kenichiro Doi, Mark R. Conaway, Shantu Amin, David F. Claxton, Hong-Gang Wang, Mark Kester, Myles C. Cabot, David J. Feith, Thomas P. Loughran, Jr.
Published 2019-06-01

Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia1

by Samy A.F. Morad, Terence E. Ryan, P. Darrell Neufer, Tonya N. Zeczycki, Traci S. Davis, Matthew R. MacDougall, Todd E. Fox, Su-Fern Tan, David J. Feith, Thomas P. Loughran, Jr., Mark Kester, David F. Claxton, Brian M. Barth, Tye G. Deering, Myles C. Cabot
Published 2016-07-01

Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells

by Li-Pin Kao, Samy A.F. Morad, Traci S. Davis, Matthew R. MacDougall, Miki Kassai, Noha Abdelmageed, Todd E. Fox, Mark Kester, Thomas P. Loughran, Jr., Jose' L. Abad, Gemma Fabrias, Su-Fern Tan, David J. Feith, David F. Claxton, Sarah Spiegel, Kelsey H. Fisher-Wellman, Myles C. Cabot
Published 2019-09-01