Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation

by Su-Fern Tan, Wendy Dunton, Xin Liu, Todd E. Fox, Samy A.F. Morad, Dhimant Desai, Kenichiro Doi, Mark R. Conaway, Shantu Amin, David F. Claxton, Hong-Gang Wang, Mark Kester, Myles C. Cabot, David J. Feith, Thomas P. Loughran, Jr.
Published 2019-06-01

The PI3K/AKT Pathway Inhibitor ISC-4 Induces Apoptosis and Inhibits Growth of Leukemia in Preclinical Models of Acute Myeloid Leukemia

by Charyguly Annageldiyev, Charyguly Annageldiyev, Su-Fern Tan, Shreya Thakur, Pavan Kumar Dhanyamraju, Srinivasa R. Ramisetti, Preeti Bhadauria, Jacob Schick, Zheng Zeng, Varun Sharma, Wendy Dunton, Sinisa Dovat, Dhimant Desai, Dhimant Desai, Hong Zheng, Hong Zheng, David J. Feith, David J. Feith, Thomas P. Loughran, Thomas P. Loughran, Shantu Amin, Shantu Amin, Arun K. Sharma, Arun K. Sharma, David Claxton, David Claxton, Arati Sharma, Arati Sharma, Arati Sharma
Published 2020-04-01