Direct quantitative determination of ceramide glycosylation in vivo: a new approach to evaluate cellular enzyme activity of glucosylceramide synthase

by Vineet Gupta, Gauri A. Patwardhan, Qian-Jin Zhang, Myles C. Cabot, S. Michal Jazwinski, Yong-Yu Liu
Published 2010-04-01

Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells

by Yong-Yu Liu, Tie Yan Han, Jing Yuan Yu, Arie Bitterman, Ahn Le, Armando E. Giuliano, Myles C. Cabot
Published 2004-05-01

Effect of B7.1 costimulation on T-cell based immunity against TAP-negative cancer can be facilitated by TAP1 expression.

by Xiao-Lin Li, Yong-Yu Liu, David Knight, Yoshinobu Odaka, J Michael Mathis, Runhua Shi, Jonathan Glass, Qian-Jin Zhang
Published 2009-07-01

Incorporation of Fluorescence Ceramide-Based HPLC Assay for Rapidly and Efficiently Assessing Glucosylceramide Synthase In Vivo

by Sachin K. Khiste, Salman B. Hosain, Yixuan Dong, Mohammad B. Uddin, Kartik R. Roy, Ronald A. Hill, Zhijun Liu, Yong-Yu Liu
Published 2017-06-01

Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models.

by Mohamed R Akl, Nehad M Ayoub, Mohamed M Mohyeldin, Belnaser A Busnena, Ahmed I Foudah, Yong-Yu Liu, Khalid A Ei Sayed
Published 2014-01-01

Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy

by Jean Christopher Chamcheu, Tithi Roy, Mohammad Burhan Uddin, Sergette Banang-Mbeumi, Roxane-Cherille N. Chamcheu, Anthony L. Walker, Yong-Yu Liu, Shile Huang
Published 2019-07-01

Curcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathway.

by Cheng-Liang Yang, Yong-Yu Liu, Ye-Gang Ma, Yi-Xue Xue, De-Gui Liu, Yi Ren, Xiao-Bai Liu, Yao Li, Zhen Li
Published 2012-01-01

Gb3‐cSrc complex in glycosphingolipid‐enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via β‐catenin–activated RNA methylation...

by Kartik R. Roy, Mohammad B. Uddin, Sagor C. Roy, Ronald A. Hill, John Marshall, Yu‐Teh Li, Jean Christopher Chamcheu, Hua Lu, Yong‐Yu Liu
Published 2020-11-01

A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis.

by Gauri A Patwardhan, Qian-Jin Zhang, Dongmei Yin, Vineet Gupta, Jianxiong Bao, Can E Senkal, Besim Ogretmen, Myles C Cabot, Girish V Shah, Paul W Sylvester, S Michal Jazwinski, Yong-Yu Liu
Published 2009-09-01

(−)-Oleocanthal Combined with Lapatinib Treatment Synergized against HER-2 Positive Breast Cancer In Vitro and In Vivo

by Abu Bakar Siddique, Hassan Y. Ebrahim, Mohamed R. Akl, Nehad M. Ayoub, Amira A. Goda, Mohamed M. Mohyeldin, Suresh K. Nagumalli, Wael M. Hananeh, Yong-Yu Liu, Sharon A. Meyer, Khalid A. El Sayed
Published 2019-02-01

Graviola (Annona muricata) Exerts Anti-Proliferative, Anti-Clonogenic and Pro-Apoptotic Effects in Human Non-Melanoma Skin Cancer UW-BCC1 and A431 Cells In Vitro: Involvement of He...

by Jean Christopher Chamcheu, Islam Rady, Roxane-Cherille N. Chamcheu, Abu Bakar Siddique, Melissa B. Bloch, Sergette Banang Mbeumi, Abiola S. Babatunde, Mohammad B. Uddin, Felicite K. Noubissi, Peter W. Jurutka, Yong-Yu Liu, Vladimir S. Spiegelman, G. Kerr Whitfield, Khalid A. El Sayed
Published 2018-06-01

Limited density of an antigen presented by RMA-S cells requires B7-1/CD28 signaling to enhance T-cell immunity at the effector phase.

by Xiao-Lin Li, Marjolein Sluijter, Elien M Doorduijn, Shubha P Kale, Harris McFerrin, Yong-Yu Liu, Yan Li, Madhusoodanan Mottamal, Xin Yao, Fengkun Du, Baihan Gu, Kim Hoang, Yen H Nguyen, Nichelle Taylor, Chelsea R Stephens, Thorbald van Hall, Qian-Jin Zhang
Published 2014-01-01