Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions

by Ernst, Jason, Melnikov, Alexandre, Zhang, Xiaolan, Wang, Li, Rogov, Peter L, Mikkelsen, Tarjei, Kellis, Manolis
Published 2017

Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay

by Kheradpour, Pouya, Kellis, Manolis, Ernst, Jason, Melnikov, Alexandre, Rogov, Peter, Wang, Li, Zhang, Xiaolan, Alston, Jessica, Mikkelsen, Tarjei Sigurd
Published 2013

Systematic dissection of genomic features determining transcription factor binding and enhancer function

by Zhang, Xiaolan, Wang, Li, Melnikov, Alexandre, Rogov, Peter, Tewhey, Ryan, Isakova, Alina, Deplancke, Bart, Bernstein, Bradley E., Mikkelsen, Tarjei S., Grossman, Sharon Rachel, Engreitz, Jesse Michael, Lander, Eric Steven
Published 2017

Rapid dissection and model-based optimization of inducible enhancers in human cells using a massively parallel reporter assay

by Melnikov, Alexandre, Murugan, Anand, Zhang, Xiaolan, Tesileanu, Tiberiu, Wang, Li, Rogov, Peter, Feizi-Khankandi, Soheil, Gnirke, Andreas, Callan Jr, Curtis G., Kinney, Justin B., Kellis, Manolis, Lander, Eric S., Mikkelsen, Tarjei Sigurd 1978-
Published 2012

Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

by Sanborn, Adrian L., Rao, Suhas S. P., Huang, Su-Chen, Durand, Neva C., Huntley, Miriam H., Jewett, Andrew I., Bochkov, Ivan D., Chinnappan, Dharmaraj, Cutkosky, Ashok, Li, Jian, Geeting, Kristopher P., Gnirke, Andreas, Melnikov, Alexandre, McKenna, Doug, Stamenova, Elena K., Aiden, Erez Lieberman, Lander, Eric Steven
Published 2017