Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response.

by Vyacheslav M Labunskyy, Maxim V Gerashchenko, Joe R Delaney, Alaattin Kaya, Brian K Kennedy, Matt Kaeberlein, Vadim N Gladyshev
Published 2014-01-01

Molecular signatures of aneuploidy-driven adaptive evolution

by Alaattin Kaya, Marco Mariotti, Alexander Tyshkovskiy, Xuming Zhou, Michelle L. Hulke, Siming Ma, Maxim V. Gerashchenko, Amnon Koren, Vadim N. Gladyshev
Published 2020-01-01

Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation.

by Amy E O'Connell, Maxim V Gerashchenko, Marie-Francoise O'Donohue, Samantha M Rosen, Eric Huntzinger, Diane Gleeson, Antonella Galli, Edward Ryder, Siqi Cao, Quinn Murphy, Shideh Kazerounian, Sarah U Morton, Klaus Schmitz-Abe, Vadim N Gladyshev, Pierre-Emmanuel Gleizes, Bertrand Séraphin, Pankaj B Agrawal
Published 2019-02-01

Adaptations to a Subterranean Environment and Longevity Revealed by the Analysis of Mole Rat Genomes

by Xiaodong Fang, Inge Seim, Zhiyong Huang, Maxim V. Gerashchenko, Zhiqiang Xiong, Anton A. Turanov, Yabing Zhu, Alexei V. Lobanov, Dingding Fan, Sun Hee Yim, Xiaoming Yao, Siming Ma, Lan Yang, Sang-Goo Lee, Eun Bae Kim, Roderick T. Bronson, Radim Šumbera, Rochelle Buffenstein, Xin Zhou, Anders Krogh, Thomas J. Park, Guojie Zhang, Jun Wang, Vadim N. Gladyshev
Published 2014-09-01