Vadim N. Gladyshev

Vadim N. Gladyshev is a professor of medicine at Brigham and Women's Hospital, Harvard Medical School, who specializes in antioxidant biology. He is known for his characterization of the human selenoproteome. He is also known for his work on the effects of aging in humans. He has conducted studies on whether organisms can acquire cellular damage from their food; the role selenium plays as a micro-nutrient with significant health benefits; In 2013 he won the NIH Pioneer Award.

In 2021, he was elected member of the U. S. National Academy of Sciences. Provided by Wikipedia
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  1. 1
    Trends in selenium utilization in marine microbial world revealed through the analysis of the global ocean sampling (GOS) project.
    by Yan Zhang, Vadim N Gladyshev
    Published 2008-06-01
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  2. 2
    A structure-based approach for detection of thiol oxidoreductases and their catalytic redox-active cysteine residues.
    by Stefano M Marino, Vadim N Gladyshev
    Published 2009-05-01
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  3. 3
    Different catalytic mechanisms in mammalian selenocysteine- and cysteine-containing methionine-R-sulfoxide reductases.
    by Hwa-Young Kim, Vadim N Gladyshev
    Published 2005-12-01
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  4. 4
    Comparative genomic analyses of copper transporters and cuproproteomes reveal evolutionary dynamics of copper utilization and its link to oxygen.
    by Perry G Ridge, Yan Zhang, Vadim N Gladyshev
    Published 2008-01-01
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  5. 5
    Selenium Deficiency Is Associated with Pro-longevity Mechanisms
    by Sun Hee Yim, Clary B. Clish, Vadim N. Gladyshev
    Published 2019-05-01
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  6. 6
    Structural analysis of glutaredoxin domain of Mus musculus thioredoxin glutathione reductase.
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  7. 7
    A whole lifespan mouse multi-tissue DNA methylation clock
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  8. 8
    Analysis of cancer genomes reveals basic features of human aging and its role in cancer development
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  9. 9
    Patterns of Aging Biomarkers, Mortality, and Damaging Mutations Illuminate the Beginning of Aging and Causes of Early-Life Mortality
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  10. 10
    Abrogated thioredoxin system causes increased sensitivity to TNF-α-induced apoptosis via enrichment of p-ERK 1/2 in the nucleus.
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  11. 11
    Diversity of protein and mRNA forms of mammalian methionine sulfoxide reductase B1 due to intronization and protein processing.
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  12. 12
    A naked mole rat iPSC line expressing drug-inducible mouse pluripotency factors developed from embryonic fibroblasts
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  13. 13
    Hydrogen peroxide probes directed to different cellular compartments.
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  14. 14
    Characterization of mammalian selenoprotein o: a redox-active mitochondrial protein.
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  15. 15
    Human Gut Microbiome Aging Clock Based on Taxonomic Profiling and Deep Learning
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  16. 16
    Mouse Models Targeting Selenocysteine tRNA Expression for Elucidating the Role of Selenoproteins in Health and Development
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  17. 17
    Germline burden of rare damaging variants negatively affects human healthspan and lifespan
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  18. 18
    CTELS: A Cell-Free System for the Analysis of Translation Termination Rate
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  19. 19
    Differences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for Therapy
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  20. 20
    svist4get: a simple visualization tool for genomic tracks from sequencing experiments
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