HIV-1 immunogens and strategies to drive antibody responses towards neutralization breadth

by Jelle van Schooten, Marit J. van Gils
Published 2018-11-01

Genome-wide association study on the development of cross-reactive neutralizing antibodies in HIV-1 infected individuals.

by Zelda Euler, Marit J van Gils, Brigitte D Boeser-Nunnink, Hanneke Schuitemaker, Daniëlle van Manen
Published 2013-01-01

HIV-1 envelope glycoprotein resistance to monoclonal antibody 2G12 is subject-specific and context-dependent in macaques and humans.

by Delphine C Malherbe, Rogier W Sanders, Marit J van Gils, Byung Park, Michelle M Gomes, Hanneke Schuitemaker, Susan Barnett, Nancy L Haigwood
Published 2013-01-01

Influenza A Virus Hemagglutinin Trimer, Head and Stem Proteins Identify and Quantify Different Hemagglutinin-Specific B Cell Subsets in Humans

by Aafke Aartse, Dirk Eggink, Mathieu Claireaux, Sarah van Leeuwen, Petra Mooij, Willy M. Bogers, Rogier W. Sanders, Gerrit Koopman, Marit J. van Gils
Published 2021-07-01

Lower Broadly Neutralizing Antibody Responses in Female Versus Male HIV-1 Infected Injecting Drug Users

by Zelda EULER, Tom L. VAN DEN KERKHOF, Roger D. KOUYOS, Damien C. TULLY, Todd M. ALLEN, Alexandra TRKOLA, Rogier W. SANDERS, Hanneke SCHUITEMAKER, Marit J. VAN GILS
Published 2019-04-01

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.

by Alba Torrents de la Peña, Kimmo Rantalainen, Christopher A Cottrell, Joel D Allen, Marit J van Gils, Jonathan L Torres, Max Crispin, Rogier W Sanders, Andrew B Ward
Published 2019-07-01

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies.

by Laura E McCoy, Emilia Falkowska, Katie J Doores, Khoa Le, Devin Sok, Marit J van Gils, Zelda Euler, Judith A Burger, Michael S Seaman, Rogier W Sanders, Hanneke Schuitemaker, Pascal Poignard, Terri Wrin, Dennis R Burton
Published 2015-08-01

An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain

by Nicholas C. Wu, Meng Yuan, Hejun Liu, Chang-Chun D. Lee, Xueyong Zhu, Sandhya Bangaru, Jonathan L. Torres, Tom G. Caniels, Philip J.M. Brouwer, Marit J. van Gils, Rogier W. Sanders, Andrew B. Ward, Ian A. Wilson
Published 2020-10-01

The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection.

by Tysheena P Charles, Samantha L Burton, Prabhu S Arunachalam, Christopher A Cottrell, Leigh M Sewall, Venkata S Bollimpelli, Sailaja Gangadhara, Antu K Dey, Andrew B Ward, George M Shaw, Eric Hunter, Rama R Amara, Bali Pulendran, Marit J van Gils, Cynthia A Derdeyn
Published 2021-02-01

Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.

by P J Klasse, Celia C LaBranche, Thomas J Ketas, Gabriel Ozorowski, Albert Cupo, Pavel Pugach, Rajesh P Ringe, Michael Golabek, Marit J van Gils, Miklos Guttman, Kelly K Lee, Ian A Wilson, Salvatore T Butera, Andrew B Ward, David C Montefiori, Rogier W Sanders, John P Moore
Published 2016-09-01

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

by Laura E. McCoy, Marit J. van Gils, Gabriel Ozorowski, Terrence Messmer, Bryan Briney, James E. Voss, Daniel W. Kulp, Matthew S. Macauley, Devin Sok, Matthias Pauthner, Sergey Menis, Christopher A. Cottrell, Jonathan L. Torres, Jessica Hsueh, William R. Schief, Ian A. Wilson, Andrew B. Ward, Rogier W. Sanders, Dennis R. Burton
Published 2016-08-01

Time since SARS-CoV-2 infection and humoral immune response following BNT162b2 mRNA vaccination

by Brent Appelman, Karlijn van der Straten, A.H. Ayesha Lavell, Michiel Schinkel, Marleen A. Slim, Meliawati Poniman, Judith A. Burger, Melissa Oomen, Khadija Tejjani, Alexander P.J. Vlaar, W. Joost Wiersinga, Yvo M. Smulders, Lonneke A. van Vught, Rogier W. Sanders, Marit J. van Gils, Marije K. Bomers, Jonne J. Sikkens
Published 2021-10-01

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies.

by Rogier W Sanders, Ronald Derking, Albert Cupo, Jean-Philippe Julien, Anila Yasmeen, Natalia de Val, Helen J Kim, Claudia Blattner, Alba Torrents de la Peña, Jacob Korzun, Michael Golabek, Kevin de Los Reyes, Thomas J Ketas, Marit J van Gils, C Richter King, Ian A Wilson, Andrew B Ward, P J Klasse, John P Moore
Published 2013-09-01

The effect of spike mutations on SARS-CoV-2 neutralization

by Chloe Rees-Spear, Luke Muir, Sarah A. Griffith, Judith Heaney, Yoann Aldon, Jonne L. Snitselaar, Peter Thomas, Carl Graham, Jeffrey Seow, Nayung Lee, Annachiara Rosa, Chloe Roustan, Catherine F. Houlihan, Rogier W. Sanders, Ravindra K. Gupta, Peter Cherepanov, Hans J. Stauss, Eleni Nastouli, Katie J. Doores, Marit J. van Gils, Laura E. McCoy
Published 2021-03-01

Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles

by Philip J. M. Brouwer, Aleksandar Antanasijevic, Marlon de Gast, Joel D. Allen, Tom P. L. Bijl, Anila Yasmeen, Rashmi Ravichandran, Judith A. Burger, Gabriel Ozorowski, Jonathan L. Torres, Celia LaBranche, David C. Montefiori, Rajesh P. Ringe, Marit J. van Gils, John P. Moore, Per Johan Klasse, Max Crispin, Neil P. King, Andrew B. Ward, Rogier W. Sanders
Published 2021-02-01

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

by P J Klasse, Thomas J Ketas, Christopher A Cottrell, Gabriel Ozorowski, Gargi Debnath, Diawoye Camara, Erik Francomano, Pavel Pugach, Rajesh P Ringe, Celia C LaBranche, Marit J van Gils, Christine A Bricault, Dan H Barouch, Shane Crotty, Guido Silvestri, Sudhir Kasturi, Bali Pulendran, Ian A Wilson, David C Montefiori, Rogier W Sanders, Andrew B Ward, John P Moore
Published 2018-02-01

Dynamics of antibodies to SARS‐CoV‐2 in convalescent plasma donors

by Maurice Steenhuis, Gerard vanMierlo, Ninotska IL Derksen, Pleuni Ooijevaar‐de Heer, Simone Kruithof, Floris L Loeff, Lea C Berkhout, Federica Linty, Chantal Reusken, Johan Reimerink, Boris Hogema, Hans Zaaijer, Leo van deWatering, Francis Swaneveld, Marit J vanGils, Berend Jan Bosch, S Marieke vanHam, Anja tenBrinke, Gestur Vidarsson, Ellen C van derSchoot, Theo Rispens
Published 2021-01-01

Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

by Ronald Derking, Joel D. Allen, Christopher A. Cottrell, Kwinten Sliepen, Gemma E. Seabright, Wen-Hsin Lee, Yoann Aldon, Kimmo Rantalainen, Aleksandar Antanasijevic, Jeffrey Copps, Anila Yasmeen, Albert Cupo, Victor M. Cruz Portillo, Meliawati Poniman, Niki Bol, Patricia van der Woude, Steven W. de Taeye, Tom L.G.M. van den Kerkhof, P.J. Klasse, Gabriel Ozorowski, Marit J. van Gils, John P. Moore, Andrew B. Ward, Max Crispin, Rogier W. Sanders
Published 2021-04-01

Fusion peptide priming reduces immune responses to HIV-1 envelope trimer base

by Angela R. Corrigan, Hongying Duan, Cheng Cheng, Christopher A. Gonelli, Li Ou, Kai Xu, Megan E. DeMouth, Hui Geng, Sandeep Narpala, Sarah O’Connell, Baoshan Zhang, Tongqing Zhou, Manjula Basappa, Jeffrey C. Boyington, Steven J. Chen, Sijy O’Dell, Amarendra Pegu, Tyler Stephens, Yaroslav Tsybovsky, Jelle van Schooten, John P. Todd, Shuishu Wang, Nicole A. Doria-Rose, Kathryn E. Foulds, Richard A. Koup, Adrian B. McDermott, Marit J. van Gils, Peter D. Kwong, John R. Mascola
Published 2021-04-01

Human Milk from Previously COVID-19-Infected Mothers: The Effect of Pasteurization on Specific Antibodies and Neutralization Capacity

by Britt J. van Keulen, Michelle Romijn, Albert Bondt, Kelly A. Dingess, Eva Kontopodi, Karlijn van der Straten, Maurits A. den Boer, Judith A. Burger, Meliawati Poniman, Berend J. Bosch, Philip J. M. Brouwer, Christianne J. M. de Groot, Max Hoek, Wentao Li, Dasja Pajkrt, Rogier W. Sanders, Anne Schoonderwoerd, Sem Tamara, Rian A. H. Timmermans, Gestur Vidarsson, Koert J. Stittelaar, Theo T. Rispens, Kasper A. Hettinga, Marit J. van Gils, Albert J. R. Heck, Johannes B. van Goudoever
Published 2021-05-01