Stabilizing HIV-1 envelope glycoprotein trimers to induce neutralizing antibodies

by Alba Torrents de la Peña, Rogier W. Sanders
Published 2018-09-01

Enhanced immunogenicity of HIV-1 envelope gp140 proteins fused to APRIL.

by Gözde Isik, Kwinten Sliepen, Thijs van Montfort, Rogier W Sanders
Published 2014-01-01

Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry.

by Reem Berro, Rogier W Sanders, Min Lu, Per J Klasse, John P Moore
Published 2009-08-01

Chimeric HIV-1 envelope glycoproteins with potent intrinsic granulocyte-macrophage colony-stimulating factor (GM-CSF) activity.

by Gözde Isik, Thijs van Montfort, Maikel Boot, Viviana Cobos Jiménez, Neeltje A Kootstra, Rogier W Sanders
Published 2013-01-01

Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide

by Sonu Kumar, Anita Sarkar, Pavel Pugach, Rogier W. Sanders, John P. Moore, Andrew B. Ward, Ian A. Wilson
Published 2019-02-01

Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer

by Kwinten Sliepen, Thijs van Montfort, Gabriel Ozorowski, Laura K. Pritchard, Max Crispin, Andrew B. Ward, Rogier W. Sanders
Published 2015-10-01

Dendritic cell-induced activation of latent HIV-1 provirus in actively proliferating primary T lymphocytes.

by Renée M van der Sluis, Thijs van Montfort, Georgios Pollakis, Rogier W Sanders, Dave Speijer, Ben Berkhout, Rienk E Jeeninga
Published 2013-03-01

The Envelope-Based Fusion Antigen GP120C14K Forming Hexamer-Like Structures Triggers T Cell and Neutralizing Antibody Responses Against HIV-1

by Suresh C. Raman, Ernesto Mejías-Pérez, Carmen E. Gomez, Juan García-Arriaza, Beatriz Perdiguero, Aneesh Vijayan, Mar Pérez-Ruiz, Ana Cuervo, César Santiago, Carlos Oscar S. Sorzano, Cristina Sánchez-Corzo, Christiane Moog, Judith A. Burger, Anna Schorcht, Rogier W. Sanders, Rogier W. Sanders, José L. Carrascosa, Mariano Esteban
Published 2019-12-01

HIV-1 autologous antibody neutralization associates with mother to child transmission.

by Elly Baan, Anthony de Ronde, Martijn Stax, Rogier W Sanders, Stanley Luchters, Joseph Vyankandondera, Joep M Lange, Georgios Pollakis, William A Paxton
Published 2013-01-01

HIV-1 envelope glycoprotein resistance to monoclonal antibody 2G12 is subject-specific and context-dependent in macaques and humans.

by Delphine C Malherbe, Rogier W Sanders, Marit J van Gils, Byung Park, Michelle M Gomes, Hanneke Schuitemaker, Susan Barnett, Nancy L Haigwood
Published 2013-01-01

An HIV-1 envelope glycoprotein trimer with an embedded IL-21 domain activates human B cells.

by Gözde Isik, Nancy P Y Chung, Thijs van Montfort, Sergey Menis, Katie Matthews, William R Schief, John P Moore, Rogier W Sanders
Published 2013-01-01

Influenza A Virus Hemagglutinin Trimer, Head and Stem Proteins Identify and Quantify Different Hemagglutinin-Specific B Cell Subsets in Humans

by Aafke Aartse, Dirk Eggink, Mathieu Claireaux, Sarah van Leeuwen, Petra Mooij, Willy M. Bogers, Rogier W. Sanders, Gerrit Koopman, Marit J. van Gils
Published 2021-07-01

Variable Domain N-Linked Glycans Acquired During Antigen-Specific Immune Responses Can Contribute to Immunoglobulin G Antibody Stability

by Fleur S. van de Bovenkamp, Fleur S. van de Bovenkamp, Ninotska I. L. Derksen, Ninotska I. L. Derksen, Mariëlle J. van Breemen, Steven W. de Taeye, Steven W. de Taeye, Steven W. de Taeye, Pleuni Ooijevaar-de Heer, Pleuni Ooijevaar-de Heer, Rogier W. Sanders, Rogier W. Sanders, Theo Rispens, Theo Rispens
Published 2018-04-01

Optimized Hepatitis C Virus (HCV) E2 Glycoproteins and their Immunogenicity in Combination with MVA-HCV

by María Q. Marín, Kwinten Sliepen, Juan García-Arriaza, Sylvie M. Koekkoek, Patricia Pérez, Carlos Óscar S. Sorzano, Carmen E. Gómez, Rogier W. Sanders, Mariano Esteban
Published 2020-08-01

Clinical adjuvant combinations stimulate potent B-cell responses in vitro by activating dermal dendritic cells.

by Katie Matthews, Nancy P Y Chung, Per Johan Klasse, Magda Moutaftsi, Darrick Carter, André M Salazar, Steven G Reed, Rogier W Sanders, John P Moore
Published 2013-01-01

Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals.

by Jorge Carrillo, Luis Manuel Molinos-Albert, Maria Luisa Rodríguez de la Concepción, Silvia Marfil, Elisabet García, Ronald Derking, Rogier W Sanders, Bonaventura Clotet, Julià Blanco
Published 2015-01-01

Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide

by Erik Lee Snapp, Nicholas McCaul, Matthias Quandte, Zuzana Cabartova, Ilja Bontjer, Carolina Källgren, IngMarie Nilsson, Aafke Land, Gunnar von Heijne, Rogier W Sanders, Ineke Braakman
Published 2017-07-01

Lower Broadly Neutralizing Antibody Responses in Female Versus Male HIV-1 Infected Injecting Drug Users

by Zelda EULER, Tom L. VAN DEN KERKHOF, Roger D. KOUYOS, Damien C. TULLY, Todd M. ALLEN, Alexandra TRKOLA, Rogier W. SANDERS, Hanneke SCHUITEMAKER, Marit J. VAN GILS
Published 2019-04-01

Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers.

by Ilja Bontjer, Mark Melchers, Tommy Tong, Thijs van Montfort, Dirk Eggink, David Montefiori, William C Olson, John P Moore, James M Binley, Ben Berkhout, Rogier W Sanders
Published 2013-01-01

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.

by Alba Torrents de la Peña, Kimmo Rantalainen, Christopher A Cottrell, Joel D Allen, Marit J van Gils, Jonathan L Torres, Max Crispin, Rogier W Sanders, Andrew B Ward
Published 2019-07-01