Restoration of HCV-Specific Immune Responses with Antiviral Therapy: A Case for DAA Treatment in Acute HCV Infection

by Julia L. Casey, Jordan J. Feld, Sonya A. MacParland
Published 2019-04-01

The basis of liver regeneration: A systems biology approach

by Mamatha Bhat, Elisa Pasini, Cristina Baciu, Marc Angeli, Atul Humar, Sonya Macparland, Jordan Feld, Ian McGilvray
Published 2019-05-01

Evaluation of methods to assign cell type labels to cell clusters from single-cell RNA-sequencing data [version 2; peer review: 1 approved, 2 approved with reservations]

by J. Javier Diaz-Mejia, Elaine C. Meng, Alexander R. Pico, Sonya A. MacParland, Troy Ketela, Trevor J. Pugh, Gary D. Bader, John H. Morris
Published 2019-08-01

Evaluation of methods to assign cell type labels to cell clusters from single-cell RNA-sequencing data [version 3; peer review: 2 approved, 1 approved with reservations]

by J. Javier Diaz-Mejia, Elaine C. Meng, Alexander R. Pico, Sonya A. MacParland, Troy Ketela, Trevor J. Pugh, Gary D. Bader, John H. Morris
Published 2019-10-01

The 5th Canadian Symposium on Hepatitis C Virus: We Are Not Done Yet—Remaining Challenges in Hepatitis C

by Nicholas van Buuren, Lorraine Fradette, Jason Grebely, Alexandra King, Mel Krajden, Sonya A. MacParland, Alison Marshall, Sahar Saeed, Joyce Wilson, Marina B. Klein, Selena M. Sagan
Published 2016-01-01

Highlights of the Fourth Canadian Symposium on Hepatitis C: Moving towards a National Action Plan

by Selena M. Sagan, Benoit Dupont, Jason Grebely, Mel Krajden, Sonya A. MacParland, Jennifer F. Raven, Sahar Saeed, Jordan J. Feld, D. Lorne Tyrrell, Joyce A. Wilson
Published 2016-01-01

Determinants of Ligand Specificity and Functional Plasticity in Type I Interferon Signaling

by Duncan Kirby, Baljyot Parmar, Sepehr Fathi, Sagar Marwah, Chitra R. Nayak, Chitra R. Nayak, Vera Cherepanov, Sonya MacParland, Jordan J. Feld, Grégoire Altan-Bonnet, Anton Zilman, Anton Zilman
Published 2021-10-01

Regulatory B cells are induced in untreated HIV-1 infection and suppress HIV-1 specific T cell responses

by Liu J, Zhan W, Kim C, Lee E, Cao J, Ziegler B, Gregor A, Yue F, Huibner S, Macparland S, Clayton K, Schwartz J, Song H, Bento E, Kovacs C, Kaul R, Ostrowski M
Published 2012-09-01

Tim-3 negatively regulates cytotoxicity in exhausted CD8+ T cells in HIV infection.

by Ali Sakhdari, Shariq Mujib, Bahareh Vali, Feng Yun Yue, Sonya MacParland, Kiera Clayton, Richard Bradley Jones, Jun Liu, Erika Yue Lee, Erika Benko, Colin Kovacs, Jennifer Gommerman, Rupert Kaul, Mario A Ostrowski
Published 2012-01-01

HCV Specific IL-21 Producing T Cells but Not IL-17A Producing T Cells Are Associated with HCV Viral Control in HIV/HCV Coinfection.

by Sonya A MacParland, Saleh M Fadel, Vesna Mihajlovic, Ali Fawaz, Connie Kim, A K M Nur-Ur Rahman, Jun Liu, Rupert Kaul, Colin Kovacs, Jason Grebely, Gregory J Dore, David K Wong, Mario A Ostrowski
Published 2016-01-01

The 3rd Canadian Symposium on Hepatitis C Virus: Expanding Care in the Interferon-Free Era

by Sonya A MacParland, Marc Bilodeau, Jason Grebely, Julie Bruneau, Curtis Cooper, Marina Klein, Selena M Sagan, Norma Choucha, Louise Balfour, Frank Bialystok, Mel Krajden, Jennifer Raven, Eve Roberts, Rodney Russell, Michael Houghton, D Lorne Tyrrell, Jordan J Feld
Published 2014-01-01

IL-10-producing B cells are induced early in HIV-1 infection and suppress HIV-1-specific T cell responses.

by Jun Liu, Wei Zhan, Connie J Kim, Kiera Clayton, Hanqi Zhao, Erika Lee, Jin Chao Cao, Blake Ziegler, Alexander Gregor, Feng Yun Yue, Sanja Huibner, Sonya MacParland, Jordan Schwartz, Hai Han Song, Erika Benko, Gabor Gyenes, Colin Kovacs, Rupert Kaul, Mario Ostrowski
Published 2014-01-01

Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations

by Sonya A. MacParland, Jeff C. Liu, Xue-Zhong Ma, Brendan T. Innes, Agata M. Bartczak, Blair K. Gage, Justin Manuel, Nicholas Khuu, Juan Echeverri, Ivan Linares, Rahul Gupta, Michael L. Cheng, Lewis Y. Liu, Damra Camat, Sai W. Chung, Rebecca K. Seliga, Zigong Shao, Elizabeth Lee, Shinichiro Ogawa, Mina Ogawa, Michael D. Wilson, Jason E. Fish, Markus Selzner, Anand Ghanekar, David Grant, Paul Greig, Gonzalo Sapisochin, Nazia Selzner, Neil Winegarden, Oyedele Adeyi, Gordon Keller, Gary D. Bader, Ian D. McGilvray
Published 2018-10-01