Enhanced activation of memory, but not naïve, B cells in chronic hepatitis C virus-infected patients with cryoglobulinemia and advanced liver fibrosis.

by Deanna M Santer, Mang M Ma, Darren Hockman, Abdolamir Landi, D Lorne J Tyrrell, Michael Houghton
Published 2013-01-01

Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells.

by Deanna M Santer, Gillian E S Minty, Dominic P Golec, Julia Lu, Julia May, Afshin Namdar, Juhi Shah, Shokrollah Elahi, David Proud, Michael Joyce, D Lorne Tyrrell, Michael Houghton
Published 2020-04-01

Do patient characteristics matter when calculating sample size for eczema clinical trials?

by L. Howells, S. Gran, J. R. Chalmers, B. Stuart, M. Santer, L. Bradshaw, D. M. Gaunt, M. J. Ridd, L. A. A. Gerbens, P. I. Spuls, C. Huang, N. A. Francis, K. S. Thomas
Published 2021-09-01

A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans.

by John Lok Man Law, Chao Chen, Jason Wong, Darren Hockman, Deanna M Santer, Sharon E Frey, Robert B Belshe, Takaji Wakita, Jens Bukh, Christopher T Jones, Charles M Rice, Sergio Abrignani, D Lorne Tyrrell, Michael Houghton
Published 2013-01-01

No evidence for XMRV nucleic acids, infectious virus or anti-XMRV antibodies in Canadian patients with chronic fatigue syndrome.

by Imke Steffen, D Lorne Tyrrell, Eleanor Stein, Leilani Montalvo, Tzong-Hae Lee, Yanchen Zhou, Kai Lu, William M Switzer, Shaohua Tang, Hongwei Jia, Darren Hockman, Deanna M Santer, Michael Logan, Amir Landi, John Law, Michael Houghton, Graham Simmons
Published 2011-01-01

IL-28B is a key regulator of B- and T-cell vaccine responses against influenza.

by Adrian Egli, Deanna M Santer, Daire O'Shea, Khaled Barakat, Mohammedyaseen Syedbasha, Madeleine Vollmer, Aliyah Baluch, Rakesh Bhat, Jody Groenendyk, Michael A Joyce, Luiz F Lisboa, Brad S Thomas, Manuel Battegay, Nina Khanna, Thomas Mueller, D Lorne J Tyrrell, Michael Houghton, Atul Humar, Deepali Kumar
Published 2014-12-01