A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation

by Louise van der Weyden, Agnieszka Swiatkowska, Vivek Iyer, Anneliese O. Speak, David J. Adams
Published 2020-06-01

Successful treatment of early cutaneous squamous cell carcinoma with hypofractionated radiation therapy in an African lion (Panthera leo)

by Louise van der Weyden, Nicolize O'Dell, Alida Avenant, Paolo Pazzi, Katja N. Koeppel
Published 2021-06-01

Metastatic Cutaneous Melanoma in a White African Lioness (<i>Panthera leo</i>)

by Louise van der Weyden, Peter Caldwell, Liesl van Rooyen, Emily P. Mitchell, Nicolize O’Dell
Published 2021-08-01

Comparison of the oncogenomic landscape of canine and feline hemangiosarcoma shows novel parallels with human angiosarcoma

by Kim Wong, Latasha Ludwig, Oscar Krijgsman, David J. Adams, Geoffrey A. Wood, Louise van der Weyden
Published 2021-07-01

Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.

by Martin F Dietrich, Louise van der Weyden, Haydn M Prosser, Allan Bradley, Joachim Herz, David J Adams
Published 2010-04-01

CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation.

by Richard Hunte, Patricia Alonso, Remy Thomas, Cassandra Alexandria Bazile, Juan Carlos Ramos, Louise van der Weyden, Juan Dominguez-Bendala, Wasif Noor Khan, Noula Shembade
Published 2018-04-01

Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling.

by Rajeshree Pujari, Richard Hunte, Remy Thomas, Louise van der Weyden, Dan Rauch, Lee Ratner, Jennifer K Nyborg, Juan Carlos Ramos, Yoshimi Takai, Noula Shembade
Published 2015-03-01

Correction: Modeling Partial Monosomy for Human Chromosome 21q11.2-q21.1 Reveals Haploinsufficient Genes Influencing Behavior and Fat Deposition

by Anna M. Migdalska, Louise van der Weyden, Ozama Ismail, Jacqueline K. White, Sanger Mouse Genetics Project, Gabriela Sánchez-Andrade, Darren W. Logan, Mark J. Arends, David J. Adams
Published 2012-01-01

Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis

by Martin Del Castillo Velasco‐Herrera, Louise van derWeyden, Jeremie Nsengimana, Anneliese O. Speak, Marcela K. Sjöberg, David Timothy Bishop, Göran Jönsson, Julia Newton‐Bishop, David J. Adams
Published 2018-02-01

Modeling partial monosomy for human chromosome 21q11.2-q21.1 reveals haploinsufficient genes influencing behavior and fat deposition.

by Anna M Migdalska, Louise van der Weyden, Ozama Ismail, Jacqueline K White, Sanger Mouse Genetics Project, Gabriela Sánchez-Andrade, Darren W Logan, Mark J Arends, David J Adams
Published 2012-01-01

Correction: Modeling Partial Monosomy for Human Chromosome 21q11.2-q21.1 Reveals Haploinsufficient Genes Influencing Behavior and Fat Deposition.

by Anna M. Migdalska, Louise van der Weyden, Ozama Ismail, Jacqueline K. White, Sanger Mouse Genetics Project, Gabriela Sánchez-Andrade, Darren W. Logan, Mark J. Arends, David J. Adams
Published 2012-01-01

Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis.

by Camille A Huser, Kathryn L Gilroy, Jeroen de Ridder, Anna Kilbey, Gillian Borland, Nancy Mackay, Alma Jenkins, Margaret Bell, Pawel Herzyk, Louise van der Weyden, David J Adams, Alistair G Rust, Ewan Cameron, James C Neil
Published 2014-02-01

Tumors induce de novo steroid biosynthesis in T cells to evade immunity

by Bidesh Mahata, Jhuma Pramanik, Louise van der Weyden, Krzysztof Polanski, Gozde Kar, Angela Riedel, Xi Chen, Nuno A. Fonseca, Kousik Kundu, Lia S. Campos, Edward Ryder, Graham Duddy, Izabela Walczak, Klaus Okkenhaug, David J. Adams, Jacqueline D. Shields, Sarah A. Teichmann
Published 2020-07-01

CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation

by Louise van der Weyden, Victoria Harle, Gemma Turner, Victoria Offord, Vivek Iyer, Alastair Droop, Agnieszka Swiatkowska, Roy Rabbie, Andrew D. Campbell, Owen J. Sansom, Mercedes Pardo, Jyoti S. Choudhary, Ingrid Ferreira, Mark Tullett, Mark J. Arends, Anneliese O. Speak, David J. Adams
Published 2021-03-01

FBXO7 sensitivity of phenotypic traits elucidated by a hypomorphic allele.

by Carmen Ballesteros Reviriego, Simon Clare, Mark J Arends, Emma L Cambridge, Agnieszka Swiatkowska, Susana Caetano, Bushra Abu-Helil, Leanne Kane, Katherine Harcourt, David A Goulding, Diane Gleeson, Edward Ryder, Brendan Doe, Jacqueline K White, Louise van der Weyden, Gordon Dougan, David J Adams, Anneliese O Speak
Published 2019-01-01

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

by Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Published 2021-02-01

Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma

by Kim Wong, Louise van der Weyden, Courtney R. Schott, Alastair Foote, Fernando Constantino-Casas, Sionagh Smith, Jane M. Dobson, Elizabeth P. Murchison, Hong Wu, Iwei Yeh, Douglas R. Fullen, Nancy Joseph, Boris C. Bastian, Rajiv M. Patel, Inigo Martincorena, Carla Daniela Robles-Espinoza, Vivek Iyer, Marieke L. Kuijjer, Mark J. Arends, Thomas Brenn, Paul W. Harms, Geoffrey A. Wood, David J. Adams
Published 2019-01-01

ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma

by Mamunur Rashid, Michiel van der Horst, Thomas Mentzel, Francesca Butera, Ingrid Ferreira, Alena Pance, Arno Rütten, Bostjan Luzar, Zlatko Marusic, Nicolas de Saint Aubain, Jennifer S. Ko, Steven D. Billings, Sofia Chen, Marie Abi Daoud, James Hewinson, Sandra Louzada, Paul W. Harms, Guia Cerretelli, Carla Daniela Robles-Espinoza, Rajiv M. Patel, Louise van der Weyden, Chris Bakal, Jason L. Hornick, Mark J. Arends, Thomas Brenn, David J. Adams
Published 2019-05-01

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.

by Rebecca E McIntyre, Pavithra Lakshminarasimhan Chavali, Ozama Ismail, Damian M Carragher, Gabriela Sanchez-Andrade, Josep V Forment, Beiyuan Fu, Martin Del Castillo Velasco-Herrera, Andrew Edwards, Louise van der Weyden, Fengtang Yang, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis, Jeanne Estabel, Ferdia A Gallagher, Darren W Logan, Mark J Arends, Stephen H Tsang, Vinit B Mahajan, Cheryl L Scudamore, Jacqueline K White, Stephen P Jackson, Fanni Gergely, David J Adams
Published 2012-01-01

Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets

by Felicity Newell, Yan Kong, James S. Wilmott, Peter A. Johansson, Peter M. Ferguson, Chuanliang Cui, Zhongwu Li, Stephen H. Kazakoff, Hazel Burke, Tristan J. Dodds, Ann-Marie Patch, Katia Nones, Varsha Tembe, Ping Shang, Louise van der Weyden, Kim Wong, Oliver Holmes, Serigne Lo, Conrad Leonard, Scott Wood, Qinying Xu, Robert V. Rawson, Pamela Mukhopadhyay, Reinhard Dummer, Mitchell P. Levesque, Göran Jönsson, Xuan Wang, Iwei Yeh, Hong Wu, Nancy Joseph, Boris C. Bastian, Georgina V. Long, Andrew J. Spillane, Kerwin F. Shannon, John F. Thompson, Robyn P. M. Saw, David J. Adams, Lu Si, John V. Pearson, Nicholas K. Hayward, Nicola Waddell, Graham J. Mann, Jun Guo, Richard A. Scolyer
Published 2019-07-01