Inhibitors of the Fanconi anaemia pathway as potential antitumour agents for ovarian cancer

by Sarah J Taylor, Mark J Arends, Simon P Langdon
Published 2020-02-01

DNA mismatch repair and CD133-marked cancer stem cells in colorectal carcinoma

by Phaik-Leng Cheah, Jing Li, Lai-Meng Looi, Kean-Hooi Teoh, Diana Bee-Lan Ong, Mark J. Arends
Published 2018-09-01

Absolute measurement of the tissue origins of cell-free DNA in the healthy state and following paracetamol overdose

by Danny Laurent, Fiona Semple, Philip J. Starkey Lewis, Elaine Rose, Holly A. Black, Jennifer Coe, Stuart J. Forbes, Mark J. Arends, James W. Dear, Timothy J. Aitman
Published 2020-04-01

Correction: Modeling Partial Monosomy for Human Chromosome 21q11.2-q21.1 Reveals Haploinsufficient Genes Influencing Behavior and Fat Deposition

by Anna M. Migdalska, Louise van der Weyden, Ozama Ismail, Jacqueline K. White, Sanger Mouse Genetics Project, Gabriela Sánchez-Andrade, Darren W. Logan, Mark J. Arends, David J. Adams
Published 2012-01-01

Modeling partial monosomy for human chromosome 21q11.2-q21.1 reveals haploinsufficient genes influencing behavior and fat deposition.

by Anna M Migdalska, Louise van der Weyden, Ozama Ismail, Jacqueline K White, Sanger Mouse Genetics Project, Gabriela Sánchez-Andrade, Darren W Logan, Mark J Arends, David J Adams
Published 2012-01-01

Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations

by Robert L. Hollis, Alison M. Meynert, Michael Churchman, Tzyvia Rye, Melanie Mackean, Fiona Nussey, Mark J. Arends, Andrew H. Sims, Colin A. Semple, C. Simon Herrington, Charlie Gourley
Published 2018-01-01

Correction: Modeling Partial Monosomy for Human Chromosome 21q11.2-q21.1 Reveals Haploinsufficient Genes Influencing Behavior and Fat Deposition.

by Anna M. Migdalska, Louise van der Weyden, Ozama Ismail, Jacqueline K. White, Sanger Mouse Genetics Project, Gabriela Sánchez-Andrade, Darren W. Logan, Mark J. Arends, David J. Adams
Published 2012-01-01

Correction: Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa.

by Chinyere K Okoro, Lars Barquist, Thomas R Connor, Simon R Harris, Simon Clare, Mark P Stevens, Mark J Arends, Christine Hale, Leanne Kane, Derek J Pickard, Jennifer Hill, Katherine Harcourt, Julian Parkhill, Gordon Dougan, Robert A Kingsley
Published 2015-06-01

Signatures of adaptation in human invasive Salmonella Typhimurium ST313 populations from sub-Saharan Africa.

by Chinyere K Okoro, Lars Barquist, Thomas R Connor, Simon R Harris, Simon Clare, Mark P Stevens, Mark J Arends, Christine Hale, Leanne Kane, Derek J Pickard, Jennifer Hill, Katherine Harcourt, Julian Parkhill, Gordon Dougan, Robert A Kingsley
Published 2015-03-01

CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation

by Louise van der Weyden, Victoria Harle, Gemma Turner, Victoria Offord, Vivek Iyer, Alastair Droop, Agnieszka Swiatkowska, Roy Rabbie, Andrew D. Campbell, Owen J. Sansom, Mercedes Pardo, Jyoti S. Choudhary, Ingrid Ferreira, Mark Tullett, Mark J. Arends, Anneliese O. Speak, David J. Adams
Published 2021-03-01

FBXO7 sensitivity of phenotypic traits elucidated by a hypomorphic allele.

by Carmen Ballesteros Reviriego, Simon Clare, Mark J Arends, Emma L Cambridge, Agnieszka Swiatkowska, Susana Caetano, Bushra Abu-Helil, Leanne Kane, Katherine Harcourt, David A Goulding, Diane Gleeson, Edward Ryder, Brendan Doe, Jacqueline K White, Louise van der Weyden, Gordon Dougan, David J Adams, Anneliese O Speak
Published 2019-01-01

Infection Susceptibility in Gastric Intrinsic Factor (Vitamin B12)-Defective Mice Is Subject to Maternal Influences

by Lynda Mottram, Anneliese O. Speak, Reza M. Selek, Emma L. Cambridge, Zoe McIntyre, Leanne Kane, Subhankar Mukhopadhyay, Carolyn Grove, Amy Colin, Cordelia Brandt, Maria A. Duque-Correa, Jessica Forbester, Tu Anh Pham Nguyen, Christine Hale, George S. Vasilliou, Mark J. Arends, Brendan W. Wren, Gordon Dougan, Simon Clare
Published 2016-06-01

MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance

by Matthew J. Sale, Kathryn Balmanno, Jayeta Saxena, Eiko Ozono, Katarzyna Wojdyla, Rebecca E. McIntyre, Rebecca Gilley, Anna Woroniuk, Karen D. Howarth, Gareth Hughes, Jonathan R. Dry, Mark J. Arends, Pilar Caro, David Oxley, Susan Ashton, David J. Adams, Julio Saez-Rodriguez, Paul D. Smith, Simon J. Cook
Published 2019-05-01

Characterization of the yehUT two-component regulatory system of Salmonella enterica Serovar Typhi and Typhimurium.

by Vanessa K Wong, Derek J Pickard, Lars Barquist, Karthikeyan Sivaraman, Andrew J Page, Peter J Hart, Mark J Arends, Kathryn E Holt, Leanne Kane, Lynda F Mottram, Louise Ellison, Ruben Bautista, Chris J McGee, Sally J Kay, Thomas M Wileman, Linda J Kenney, Calman A MacLennan, Robert A Kingsley, Gordon Dougan
Published 2013-01-01

Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma

by Kim Wong, Louise van der Weyden, Courtney R. Schott, Alastair Foote, Fernando Constantino-Casas, Sionagh Smith, Jane M. Dobson, Elizabeth P. Murchison, Hong Wu, Iwei Yeh, Douglas R. Fullen, Nancy Joseph, Boris C. Bastian, Rajiv M. Patel, Inigo Martincorena, Carla Daniela Robles-Espinoza, Vivek Iyer, Marieke L. Kuijjer, Mark J. Arends, Thomas Brenn, Paul W. Harms, Geoffrey A. Wood, David J. Adams
Published 2019-01-01

ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma

by Mamunur Rashid, Michiel van der Horst, Thomas Mentzel, Francesca Butera, Ingrid Ferreira, Alena Pance, Arno Rütten, Bostjan Luzar, Zlatko Marusic, Nicolas de Saint Aubain, Jennifer S. Ko, Steven D. Billings, Sofia Chen, Marie Abi Daoud, James Hewinson, Sandra Louzada, Paul W. Harms, Guia Cerretelli, Carla Daniela Robles-Espinoza, Rajiv M. Patel, Louise van der Weyden, Chris Bakal, Jason L. Hornick, Mark J. Arends, Thomas Brenn, David J. Adams
Published 2019-05-01

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.

by Rebecca E McIntyre, Pavithra Lakshminarasimhan Chavali, Ozama Ismail, Damian M Carragher, Gabriela Sanchez-Andrade, Josep V Forment, Beiyuan Fu, Martin Del Castillo Velasco-Herrera, Andrew Edwards, Louise van der Weyden, Fengtang Yang, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis, Jeanne Estabel, Ferdia A Gallagher, Darren W Logan, Mark J Arends, Stephen H Tsang, Vinit B Mahajan, Cheryl L Scudamore, Jacqueline K White, Stephen P Jackson, Fanni Gergely, David J Adams
Published 2012-01-01