Advances in determining signaling mechanisms of ceramide and role in disease

by Jeffrey L. Stith, Fabiola N. Velazquez, Lina M. Obeid
Published 2019-05-01

Transcriptional Regulation of Sphingosine Kinase 1

by Joseph Bonica, Cungui Mao, Lina M. Obeid, Yusuf A. Hannun
Published 2020-11-01

Inhibition of sphingosine kinase-2 in a murine model of lupus nephritis.

by Ashley J Snider, Phillip Ruiz, Lina M Obeid, Jim C Oates
Published 2013-01-01

Functions of neutral ceramidase in the Golgi apparatus

by Wataru Sakamoto, Nicolas Coant, Daniel Canals, Lina M. Obeid, Yusuf A. Hannun
Published 2018-11-01

Probing de novo sphingolipid metabolism in mammalian cells utilizing mass spectrometry[S]

by Justin M. Snider, Ashley J. Snider, Lina M. Obeid, Chiara Luberto, Yusuf A. Hannun
Published 2018-01-01

Cell density-dependent reduction of dihydroceramide desaturase activity in neuroblastoma cells

by Stefka D. Spassieva, Mehrdad Rahmaniyan, Jacek Bielawski, Christopher J. Clarke, Jacqueline M. Kraveka, Lina M. Obeid
Published 2012-05-01

Co-ordinated activation of classical and novel PKC isoforms is required for PMA-induced mTORC1 activation.

by Mengling Liu, Christopher J Clarke, Mohamed F Salama, Yeon Ja Choi, Lina M Obeid, Yusuf A Hannun
Published 2017-01-01

Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism[S]

by Thomas D. Mullen, Stefka Spassieva, Russell W. Jenkins, Kazuyuki Kitatani, Jacek Bielawski, Yusuf A. Hannun, Lina M. Obeid
Published 2011-01-01

Quantification of 3-ketodihydrosphingosine using HPLC-ESI-MS/MS to study SPT activity in yeast Saccharomyces cerevisiae[S]

by Jihui Ren, Justin Snider, Michael V. Airola, Aaron Zhong, Nadia A. Rana, Lina M. Obeid, Yusuf A. Hannun
Published 2018-01-01

Loss of sphingosine kinase 1 increases lung metastases in the MMTV-PyMT mouse model of breast cancer.

by Fabiola N Velazquez, Leiqing Zhang, Valentina Viscardi, Carolena Trocchia, Yusuf A Hannun, Lina M Obeid, Ashley J Snider
Published 2021-01-01

Probing compartment-specific sphingolipids with targeted bacterial sphingomyelinases and ceramidases

by Wataru Sakamoto, Daniel Canals, Silvia Salamone, Janet Allopenna, Christopher J. Clarke, Justin Snider, Lina M. Obeid, Yusuf A. Hannun
Published 2019-11-01

Identification of an acid sphingomyelinase ceramide kinase pathway in the regulation of the chemokine CCL5 [S]

by Benjamin Newcomb, Cosima Rhein, Izolda Mileva, Rasheed Ahmad, Christopher J. Clarke, Justin Snider, Lina M. Obeid, Yusuf A. Hannun
Published 2018-01-01

Activation of p38 Mitogen-Activated Protein Kinase in Gaucher's Disease.

by Kazuyuki Kitatani, Masayuki Wada, David Perry, Toshinori Usui, Ying Sun, Lina M Obeid, Nobuo Yaegashi, Gregory A Grabowski, Yusuf A Hannun
Published 2015-01-01

Multiple actions of doxorubicin on the sphingolipid network revealed by flux analysis[S]

by Justin M. Snider, Magali Trayssac, Christopher J. Clarke, Nicholas Schwartz, Ashley J. Snider, Lina M. Obeid, Chiara Luberto, Yusuf A. Hannun
Published 2019-04-01

Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis

by Evi Houben, Walter M. Holleran, Toshiaki Yaginuma, Cungui Mao, Lina M. Obeid, Vera Rogiers, Yutaka Takagi, Peter M. Elias, Yoshikazu Uchida
Published 2006-05-01

Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides

by Magali Trayssac, Christopher J. Clarke, Jeffrey L. Stith, Justin M. Snider, Naomi Newen, Christopher R. Gault, Yusuf A. Hannun, Lina M. Obeid
Published 2021-01-01

Accumulation of long-chain glycosphingolipids during aging is prevented by caloric restriction.

by María José Hernández-Corbacho, Russell W Jenkins, Christopher J Clarke, Yusuf A Hannun, Lina M Obeid, Ashley J Snider, Leah J Siskind
Published 2011-01-01

Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway

by Jihui Ren, Essa M. Saied, Aaron Zhong, Justin Snider, Christian Ruiz, Christoph Arenz, Lina M. Obeid, Geoffrey D. Girnun, Yusuf A. Hannun
Published 2018-11-01

AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells

by Junfei Jin, Thomas D. Mullen, Qi Hou, Jacek Bielawski, Alicja Bielawska, Xiaoming Zhang, Lina M. Obeid, Yusuf A. Hannun, Yi-Te Hsu
Published 2009-12-01

Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis

by Qi Hou, Junfei Jin, Hui Zhou, Sergei A. Novgorodov, Alicja Bielawska, Zdzislaw M. Szulc, Yusuf A. Hannun, Lina M. Obeid, Yi-Te Hsu
Published 2011-02-01