Decoupling of Nrf2 Expression Promotes Mesenchymal State Maintenance in Non-Small Cell Lung Cancer

by John A. Haley, Christian F. Ruiz, Emily D. Montal, Daifeng Wang, John D. Haley, Geoffrey D. Girnun
Published 2019-10-01

Non-proteolytic ubiquitination of Hexokinase 2 by HectH9 controls tumor metabolism and cancer stem cell expansion

by Hong-Jen Lee, Chien-Feng Li, Diane Ruan, Jiabei He, Emily D. Montal, Sonja Lorenz, Geoffrey D. Girnun, Chia-Hsin Chan
Published 2019-06-01

Rapid detection of an ABT-737-sensitive primed for death state in cells using microplate-based respirometry.

by Pascaline Clerc, Gregory B Carey, Zara Mehrabian, Michael Wei, Hyehyun Hwang, Geoffrey D Girnun, Hegang Chen, Stuart S Martin, Brian M Polster
Published 2012-01-01

Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway

by Jihui Ren, Essa M. Saied, Aaron Zhong, Justin Snider, Christian Ruiz, Christoph Arenz, Lina M. Obeid, Geoffrey D. Girnun, Yusuf A. Hannun
Published 2018-11-01

Inhibition of phosphoenolpyruvate carboxykinase blocks lactate utilization and impairs tumor growth in colorectal cancer

by Emily D. Montal, Kavita Bhalla, Ruby E. Dewi, Christian F. Ruiz, John A. Haley, Ashley E. Ropell, Chris Gordon, John D. Haley, Geoffrey D. Girnun
Published 2019-08-01