Straightforward Generation of Ultrapure Off-the-Shelf Allogeneic CAR-T Cells

by Alexandre Juillerat, Diane Tkach, Ming Yang, Alex Boyne, Julien Valton, Laurent Poirot, Philippe Duchateau
Published 2020-06-01

Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells

by Román Galetto, Celine Lebuhotel, Laurent Poirot, Agnès Gouble, Maria L Toribio, Julianne Smith, Andrew Scharenberg
Published 2014-01-01

Fine and Predictable Tuning of TALEN Gene Editing Targeting for Improved T Cell Adoptive Immunotherapy

by Anne-Sophie Gautron, Alexandre Juillerat, Valérie Guyot, Jean-Marie Filhol, Emilie Dessez, Aymeric Duclert, Philippe Duchateau, Laurent Poirot
Published 2017-12-01

Modulation of chimeric antigen receptor surface expression by a small molecule switch

by Alexandre Juillerat, Diane Tkach, Brian W. Busser, Sonal Temburni, Julien Valton, Aymeric Duclert, Laurent Poirot, Stéphane Depil, Philippe Duchateau
Published 2019-07-01

Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA.

by Oscar Quintana-Bustamante, Sara Fañanas-Baquero, Israel Orman, Raul Torres, Philippe Duchateau, Laurent Poirot, Agnès Gouble, Juan A Bueren, Jose C Segovia
Published 2019-01-01

Author Correction: Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality

by Mohit Sachdeva, Brian W. Busser, Sonal Temburni, Billal Jahangiri, Anne-Sophie Gautron, Alan Maréchal, Alexandre Juillerat, Alan Williams, Stéphane Depil, Philippe Duchateau, Laurent Poirot, Julien Valton
Published 2020-05-01

Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality

by Mohit Sachdeva, Brian W. Busser, Sonal Temburni, Billal Jahangiri, Anne-Sophie Gautron, Alan Maréchal, Alexandre Juillerat, Alan Williams, Stéphane Depil, Philippe Duchateau, Laurent Poirot, Julien Valton
Published 2019-11-01

Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells

by Zita Garate, Oscar Quintana-Bustamante, Ana M. Crane, Emmanuel Olivier, Laurent Poirot, Roman Galetto, Penelope Kosinski, Collin Hill, Charles Kung, Xabi Agirre, Israel Orman, Laura Cerrato, Omaira Alberquilla, Fatima Rodriguez-Fornes, Noemi Fusaki, Felix Garcia-Sanchez, Tabita M. Maia, Maria L. Ribeiro, Julian Sevilla, Felipe Prosper, Shengfang Jin, Joanne Mountford, Guillermo Guenechea, Agnes Gouble, Juan A. Bueren, Brian R. Davis, Jose C. Segovia
Published 2015-12-01