Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells

by Román Galetto, Celine Lebuhotel, Laurent Poirot, Agnès Gouble, Maria L Toribio, Julianne Smith, Andrew Scharenberg
Published 2014-01-01

Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA.

by Oscar Quintana-Bustamante, Sara Fañanas-Baquero, Israel Orman, Raul Torres, Philippe Duchateau, Laurent Poirot, Agnès Gouble, Juan A Bueren, Jose C Segovia
Published 2019-01-01

Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™.

by Aurélie Dupuy, Julien Valton, Sophie Leduc, Jacques Armier, Roman Galetto, Agnès Gouble, Céline Lebuhotel, Anne Stary, Frédéric Pâques, Philippe Duchateau, Alain Sarasin, Fayza Daboussi
Published 2013-01-01

Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells

by Zita Garate, Oscar Quintana-Bustamante, Ana M. Crane, Emmanuel Olivier, Laurent Poirot, Roman Galetto, Penelope Kosinski, Collin Hill, Charles Kung, Xabi Agirre, Israel Orman, Laura Cerrato, Omaira Alberquilla, Fatima Rodriguez-Fornes, Noemi Fusaki, Felix Garcia-Sanchez, Tabita M. Maia, Maria L. Ribeiro, Julian Sevilla, Felipe Prosper, Shengfang Jin, Joanne Mountford, Guillermo Guenechea, Agnes Gouble, Juan A. Bueren, Brian R. Davis, Jose C. Segovia
Published 2015-12-01