Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer’s disease

by Barbara Bettegazzi, Laura Sebastian Monasor, Serena Bellani, Franca Codazzi, Lisa Michelle Restelli, Alessio Vittorio Colombo, Nikolaus Deigendesch, Stephan Frank, Takashi Saito, Takaomi C. Saido, Sven Lammich, Sabina Tahirovic, Fabio Grohovaz, Daniele Zacchetti
Published 2021-08-01

Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

by Laura Sebastian Monasor, Stephan A Müller, Alessio Vittorio Colombo, Gaye Tanrioever, Jasmin König, Stefan Roth, Arthur Liesz, Anna Berghofer, Anke Piechotta, Matthias Prestel, Takashi Saito, Takaomi C Saido, Jochen Herms, Michael Willem, Christian Haass, Stefan F Lichtenthaler, Sabina Tahirovic
Published 2020-06-01

Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia

by Alessio Colombo, Lina Dinkel, Stephan A. Müller, Laura Sebastian Monasor, Martina Schifferer, Ludovico Cantuti-Castelvetri, Jasmin König, Lea Vidatic, Tatiana Bremova-Ertl, Andrew P. Lieberman, Silva Hecimovic, Mikael Simons, Stefan F. Lichtenthaler, Michael Strupp, Susanne A. Schneider, Sabina Tahirovic
Published 2021-02-01

Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism

by Julia K Götzl, Matthias Brendel, Georg Werner, Samira Parhizkar, Laura Sebastian Monasor, Gernot Kleinberger, Alessio‐Vittorio Colombo, Maximilian Deussing, Matias Wagner, Juliane Winkelmann, Janine Diehl‐Schmid, Johannes Levin, Katrin Fellerer, Anika Reifschneider, Sebastian Bultmann, Peter Bartenstein, Axel Rominger, Sabina Tahirovic, Scott T Smith, Charlotte Madore, Oleg Butovsky, Anja Capell, Christian Haass
Published 2019-06-01

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

by Alessio Vittorio Colombo, Rebecca Katie Sadler, Gemma Llovera, Vikramjeet Singh, Stefan Roth, Steffanie Heindl, Laura Sebastian Monasor, Aswin Verhoeven, Finn Peters, Samira Parhizkar, Frits Kamp, Mercedes Gomez de Aguero, Andrew J MacPherson, Edith Winkler, Jochen Herms, Corinne Benakis, Martin Dichgans, Harald Steiner, Martin Giera, Christian Haass, Sabina Tahirovic, Arthur Liesz
Published 2021-04-01

Relationship between IGF-1 and body weight in inflammatory bowel diseases: Cellular and molecular mechanisms involved

by Luis G. Guijarro, David Cano-Martínez, M.Val Toledo-Lobo, Patricia Sanmartín Salinas, María Chaparro, Ana M. Gómez-Lahoz, Sofía Zoullas, Rosa Rodríguez-Torres, Irene D. Román, Laura Sebastián Monasor, Lidia Ruiz-Llorente, María del Carmen Boyano-Adánez, Iván Guerra, Marisa Iborra, José Luis Cabriada, Luis Bujanda, Carlos Taxonera, Valle García-Sánchez, Ignacio Marín-Jiménez, Manuel Barreiro-de Acosta, Isabel Vera, María Dolores Martín-Arranz, Francisco Mesonero, Laura Sempere, Fernando Gomollón, Joaquín Hinojosa, Melchor Alvarez-Mon, Javier P. Gisbert, Miguel A. Ortega, Borja Hernández-Breijo, on behalf of the PREDICROHN study group from GETECCU
Published 2021-12-01