Helicobacter pylori in relation to asthma and allergy modified by abdominal obesity: The HUNT study in Norway

by Eivind Ness-Jensen, Arnulf Langhammer, Kristian Hveem, Yunxia Lu
Published 2019-01-01

Genetic Effects on Longitudinal Changes from Healthy to Adverse Weight and Metabolic Status – The HUNT Study.

by Kirsti Kvaløy, Jostein Holmen, Kristian Hveem, Turid Lingaas Holmen
Published 2015-01-01

A Validated Clinical Risk Prediction Model for Lung Cancer in Smokers of All Ages and Exposure Types: A HUNT Study

by Maria Markaki, Ioannis Tsamardinos, Arnulf Langhammer, Vincenzo Lagani, Kristian Hveem, Oluf Dimitri Røe
Published 2018-05-01

Domesticated Animal Biobanking: Land of Opportunity.

by Linn F Groeneveld, Sigbjørn Gregusson, Bernt Guldbrandtsen, Sipke J Hiemstra, Kristian Hveem, Juha Kantanen, Hannes Lohi, Lina Stroemstedt, Peer Berg
Published 2016-07-01

The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey)

by Øyvind Helgeland, Jens K. Hertel, Anders Molven, Helge Ræder, Carl G. P. Platou, Kristian Midthjell, Kristian Hveem, Ottar Nygård, Pål R. Njølstad, Stefan Johansson
Published 2015-01-01

Pre-analytical sample quality: metabolite ratios as an intrinsic marker for prolonged room temperature exposure of serum samples.

by Gabriele Anton, Rory Wilson, Zhong-Hao Yu, Cornelia Prehn, Sven Zukunft, Jerzy Adamski, Margit Heier, Christa Meisinger, Werner Römisch-Margl, Rui Wang-Sattler, Kristian Hveem, Bruce Wolfenbuttel, Annette Peters, Gabi Kastenmüller, Melanie Waldenberger
Published 2015-01-01

Metabolic syndrome and the plasma proteome: from association to causation

by Mohamed A. Elhadad, Rory Wilson, Shaza B. Zaghlool, Cornelia Huth, Christian Gieger, Harald Grallert, Johannes Graumann, Wolfgang Rathmann, Wolfgang Koenig, Moritz F. Sinner, Kristian Hveem, Karsten Suhre, Barbara Thorand, Christian Jonasson, Melanie Waldenberger, Annette Peters
Published 2021-05-01

Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth

by Øyvind Helgeland, Marc Vaudel, Petur B. Juliusson, Oddgeir Lingaas Holmen, Julius Juodakis, Jonas Bacelis, Bo Jacobsson, Haakon Lindekleiv, Kristian Hveem, Rolv Terje Lie, Gun Peggy Knudsen, Camilla Stoltenberg, Per Magnus, Jørn V. Sagen, Anders Molven, Stefan Johansson, Pål Rasmus Njølstad
Published 2019-10-01

Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals.

by Yingleong Chan, Oddgeir L Holmen, Andrew Dauber, Lars Vatten, Aki S Havulinna, Frank Skorpen, Kirsti Kvaløy, Kaisa Silander, Thutrang T Nguyen, Cristen Willer, Michael Boehnke, Markus Perola, Aarno Palotie, Veikko Salomaa, Kristian Hveem, Timothy M Frayling, Joel N Hirschhorn, Michael N Weedon
Published 2011-12-01

MDM2 promoter SNP344T>A (rs1196333) status does not affect cancer risk.

by Stian Knappskog, Liv B Gansmo, Pål Romundstad, Merete Bjørnslett, Jone Trovik, Jan Sommerfelt-Pettersen, Erik Løkkevik, Norwegian Breast Cancer Group trial NBCG VI, Rob A E M Tollenaar, Caroline Seynaeve, Peter Devilee, Helga B Salvesen, Anne Dørum, Kristian Hveem, Lars Vatten, Per E Lønning
Published 2012-01-01

A Novel Variant in APOB Gene Causes Extremely Low LDL-C Without Known Adverse Effects

by Ida Surakka, PhD, Whitney E. Hornsby, PhD, Linda Farhat, MS, Melvyn Rubenfire, MD, Lars G. Fritsche, PhD, Kristian Hveem, MD, PhD, Y. Eugene Chen, MD, PhD, Robert D. Brook, MD, Cristen J. Willer, PhD, Richard L. Weinberg, MD, PhD
Published 2020-05-01

Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis

by Sarah E. Graham, Jonas B. Nielsen, Matthew Zawistowski, Wei Zhou, Lars G. Fritsche, Maiken E. Gabrielsen, Anne Heidi Skogholt, Ida Surakka, Whitney E. Hornsby, Damian Fermin, Daniel B. Larach, Sachin Kheterpal, Chad M. Brummett, Seunggeun Lee, Hyun Min Kang, Goncalo R. Abecasis, Solfrid Romundstad, Stein Hallan, Matthew G. Sampson, Kristian Hveem, Cristen J. Willer
Published 2019-04-01

Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability.

by Serena Sanna, Bingshan Li, Antonella Mulas, Carlo Sidore, Hyun M Kang, Anne U Jackson, Maria Grazia Piras, Gianluca Usala, Giuseppe Maninchedda, Alessandro Sassu, Fabrizio Serra, Maria Antonietta Palmas, William H Wood, Inger Njølstad, Markku Laakso, Kristian Hveem, Jaakko Tuomilehto, Timo A Lakka, Rainer Rauramaa, Michael Boehnke, Francesco Cucca, Manuela Uda, David Schlessinger, Ramaiah Nagaraja, Gonçalo R Abecasis
Published 2011-07-01

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

by Ida Surakka, Lars G. Fritsche, Wei Zhou, Joshua Backman, Jack A. Kosmicki, Haocheng Lu, Ben Brumpton, Jonas B. Nielsen, Maiken E. Gabrielsen, Anne Heidi Skogholt, Brooke Wolford, Sarah E. Graham, Y. Eugene Chen, Seunggeun Lee, Hyun Min Kang, Arnulf Langhammer, Siri Forsmo, Bjørn O. Åsvold, Unnur Styrkarsdottir, Hilma Holm, Daniel Gudbjartsson, Kari Stefansson, Aris Baras, Regeneron Genetics Center, Goncalo R. Abecasis, Kristian Hveem, Cristen J. Willer
Published 2020-10-01

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

by Ben Brumpton, Eleanor Sanderson, Karl Heilbron, Fernando Pires Hartwig, Sean Harrison, Gunnhild Åberge Vie, Yoonsu Cho, Laura D. Howe, Amanda Hughes, Dorret I. Boomsma, Alexandra Havdahl, John Hopper, Michael Neale, Michel G. Nivard, Nancy L. Pedersen, Chandra A. Reynolds, Elliot M. Tucker-Drob, Andrew Grotzinger, Laurence Howe, Tim Morris, Shuai Li, The Within-family Consortium, The 23andMe Research Team, Adam Auton, Frank Windmeijer, Wei-Min Chen, Johan Håkon Bjørngaard, Kristian Hveem, Cristen Willer, David M. Evans, Jaakko Kaprio, George Davey Smith, Bjørn Olav Åsvold, Gibran Hemani, Neil M. Davies
Published 2020-07-01

Genome-wide analysis yields new loci associating with aortic valve stenosis

by Anna Helgadottir, Gudmar Thorleifsson, Solveig Gretarsdottir, Olafur A. Stefansson, Vinicius Tragante, Rosa B. Thorolfsdottir, Ingileif Jonsdottir, Thorsteinn Bjornsson, Valgerdur Steinthorsdottir, Niek Verweij, Jonas B. Nielsen, Wei Zhou, Lasse Folkersen, Andreas Martinsson, Mahyar Heydarpour, Siddharth Prakash, Gylfi Oskarsson, Tomas Gudbjartsson, Arnar Geirsson, Isleifur Olafsson, Emil L. Sigurdsson, Peter Almgren, Olle Melander, Anders Franco-Cereceda, Anders Hamsten, Lars Fritsche, Maoxuan Lin, Bo Yang, Whitney Hornsby, Dongchuan Guo, Chad M. Brummett, Gonçalo Abecasis, Michael Mathis, Dianna Milewicz, Simon C. Body, Per Eriksson, Cristen J. Willer, Kristian Hveem, Christopher Newton-Cheh, J. Gustav Smith, Ragnar Danielsen, Gudmundur Thorgeirsson, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Hilma Holm, Kari Stefansson
Published 2018-03-01

Age-of-onset information helps identify 76 genetic variants associated with allergic disease.

by Manuel A R Ferreira, Judith M Vonk, Hansjörg Baurecht, Ingo Marenholz, Chao Tian, Joshua D Hoffman, Quinta Helmer, Annika Tillander, Vilhelmina Ullemar, Yi Lu, Sarah Grosche, Franz Rüschendorf, Raquel Granell, Ben M Brumpton, Lars G Fritsche, Laxmi Bhatta, Maiken E Gabrielsen, Jonas B Nielsen, Wei Zhou, Kristian Hveem, Arnulf Langhammer, Oddgeir L Holmen, Mari Løset, Gonçalo R Abecasis, Cristen J Willer, Nima C Emami, Taylor B Cavazos, John S Witte, Agnieszka Szwajda, 23andMe Research Team, collaborators of the SHARE study, David A Hinds, Norbert Hübner, Stephan Weidinger, Patrik Ke Magnusson, Eric Jorgenson, Robert Karlsson, Lavinia Paternoster, Dorret I Boomsma, Catarina Almqvist, Young-Ae Lee, Gerard H Koppelman
Published 2020-06-01

Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes

by Heming Wang, Jacqueline M. Lane, Samuel E. Jones, Hassan S. Dashti, Hanna M. Ollila, Andrew R. Wood, Vincent T. van Hees, Ben Brumpton, Bendik S. Winsvold, Katri Kantojärvi, Teemu Palviainen, Brian E. Cade, Tamar Sofer, Yanwei Song, Krunal Patel, Simon G. Anderson, David A. Bechtold, Jack Bowden, Richard Emsley, Simon D. Kyle, Max A. Little, Andrew S. Loudon, Frank A. J. L. Scheer, Shaun M. Purcell, Rebecca C. Richmond, Kai Spiegelhalder, Jessica Tyrrell, Xiaofeng Zhu, Christer Hublin, Jaakko A. Kaprio, Kati Kristiansson, Sonja Sulkava, Tiina Paunio, Kristian Hveem, Jonas B. Nielsen, Cristen J. Willer, John-Anker Zwart, Linn B. Strand, Timothy M. Frayling, David Ray, Deborah A. Lawlor, Martin K. Rutter, Michael N. Weedon, Susan Redline, Richa Saxena
Published 2019-08-01

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

by Wei Zhou, Ben Brumpton, Omer Kabil, Julius Gudmundsson, Gudmar Thorleifsson, Josh Weinstock, Matthew Zawistowski, Jonas B. Nielsen, Layal Chaker, Marco Medici, Alexander Teumer, Silvia Naitza, Serena Sanna, Ulla T. Schultheiss, Anne Cappola, Juha Karjalainen, Mitja Kurki, Morgan Oneka, Peter Taylor, Lars G. Fritsche, Sarah E. Graham, Brooke N. Wolford, William Overton, Humaira Rasheed, Eirin B. Haug, Maiken E. Gabrielsen, Anne Heidi Skogholt, Ida Surakka, George Davey Smith, Anita Pandit, Tanmoy Roychowdhury, Whitney E. Hornsby, Jon G. Jonasson, Leigha Senter, Sandya Liyanarachchi, Matthew D. Ringel, Li Xu, Lambertus A. Kiemeney, Huiling He, Romana T. Netea-Maier, Jose I. Mayordomo, Theo S. Plantinga, Jon Hrafnkelsson, Hannes Hjartarson, Erich M. Sturgis, Aarno Palotie, Mark Daly, Cintia E. Citterio, Peter Arvan, Chad M. Brummett, Michael Boehnke, Albert de la Chapelle, Kari Stefansson, Kristian Hveem, Cristen J. Willer, Bjørn Olav Åsvold
Published 2020-08-01

Variants associated with HHIP expression have sex-differential effects on lung function [version 2; peer review: 2 approved]

by Katherine A. Fawcett, Ma'en Obeidat, Carl Melbourne, Nick Shrine, Anna L. Guyatt, Catherine John, Jian'an Luan, Anne Richmond, Marta R. Moksnes, Raquel Granell, Stefan Weiss, Medea Imboden, Sebastian May-Wilson, Pirro Hysi, Thibaud S. Boutin, Laura Portas, Claudia Flexeder, Sarah E. Harris, Carol A. Wang, Leo-Pekka Lyytikäinen, Teemu Palviainen, Rachel E. Foong, Dirk Keidel, Cosetta Minelli, Claudia Langenberg, Yohan Bossé, Maarten Van den Berge, Don D. Sin, Ke Hao, Archie Campbell, David Porteous, Sandosh Padmanabhan, Blair H. Smith, David M. Evans, Sue Ring, Arnulf Langhammer, Kristian Hveem, Cristen Willer, Ralf Ewert, Beate Stubbe, Nicola Pirastu, Lucija Klaric, Peter K. Joshi, Karina Patasova, Mangino Massimo, Ozren Polasek, John M. Starr, Stefan Karrasch, Konstantin Strauch, Thomas Meitinger, Igor Rudan, Taina Rantanen, Kirsi Pietiläinen, Mika Kähönen, Olli T. Raitakari, Graham L. Hall, Peter D. Sly, Craig E. Pennell, Jaakko Kaprio, Terho Lehtimäki, Veronique Vitart, Ian J. Deary, Debbie Jarvis, James F. Wilson, Tim Spector, Nicole Probst-Hensch, Nicholas J. Wareham, Henry Völzke, John Henderson, David P. Strachan, Ben M. Brumpton, Caroline Hayward, Ian P. Hall, Martin D. Tobin, Louise V. Wain
Published 2021-05-01