Discovery of rare variants via sequencing: implications for the design of complex trait association studies.

by Bingshan Li, Suzanne M Leal
Published 2009-05-01

Improved Variant Calling Accuracy by Merging Replicates in Whole-Exome Sequencing Studies

by Yanfeng Zhang, Bingshan Li, Chun Li, Qiuyin Cai, Wei Zheng, Jirong Long
Published 2014-01-01

Leveraging Identity-by-Descent for Accurate Genotype Inference in Family Sequencing Data.

by Bingshan Li, Qiang Wei, Xiaowei Zhan, Xue Zhong, Wei Chen, Chun Li, Jonathan Haines
Published 2015-06-01

QPLOT: A Quality Assessment Tool for Next Generation Sequencing Data

by Bingshan Li, Xiaowei Zhan, Mary-Kate Wing, Paul Anderson, Hyun Min Kang, Goncalo R. Abecasis
Published 2013-01-01

PSCAN: Spatial scan tests guided by protein structures improve complex disease gene discovery and signal variant detection

by Zheng-Zheng Tang, Gregory R. Sliwoski, Guanhua Chen, Bowen Jin, William S. Bush, Bingshan Li, John A. Capra
Published 2020-08-01

A likelihood-based framework for variant calling and de novo mutation detection in families.

by Bingshan Li, Wei Chen, Xiaowei Zhan, Fabio Busonero, Serena Sanna, Carlo Sidore, Francesco Cucca, Hyun M Kang, Gonçalo R Abecasis
Published 2012-01-01

Site-specific selection reveals selective constraints and functionality of tumor somatic mtDNA mutations

by Deyang Li, Xiaohong Du, Xu Guo, Lei Zhan, Xin Li, Chun Yin, Cheng Chen, Mingkun Li, Bingshan Li, Hushan Yang, Jinliang Xing
Published 2017-11-01

Genetic polymorphism in a VEGF-independent angiogenesis gene ANGPT1 and overall survival of colorectal cancer patients after surgical resection.

by Jingyao Dai, Shaogui Wan, Feng Zhou, Ronald E Myers, Xu Guo, Bingshan Li, Xiaoying Fu, Juan P Palazzo, Kefeng Dou, Hushan Yang, Jinliang Xing
Published 2012-01-01

Incidental Pulmonary Metastases Revealing Subcentimeter Papillary Thyroid Carcinoma

by Ruey Hu, MD, MPH, George Xu, Thomas Stricker, MD, PhD, Bingshan Li, PhD, Vivian L. Weiss, MD, PhD, Lindsay Bischoff, MD
Published 2020-09-01

Integration of circulating tumor cell and neutrophil-lymphocyte ratio to identify high-risk metastatic castration-resistant prostate cancer patients

by Weelic Chong, Zhenchao Zhang, Rui Luo, Jian Gu, Jianqing Lin, Qiang Wei, Bingshan Li, Ronald Myers, Grace Lu-Yao, William Kevin Kelly, Chun Wang, Hushan Yang
Published 2021-06-01

DRAMS: A tool to detect and re-align mixed-up samples for integrative studies of multi-omics data.

by Yi Jiang, Gina Giase, Kay Grennan, Annie W Shieh, Yan Xia, Lide Han, Quan Wang, Qiang Wei, Rui Chen, Sihan Liu, Kevin P White, Chao Chen, Bingshan Li, Chunyu Liu
Published 2020-04-01

Improved Prognostic Stratification Using Circulating Tumor Cell Clusters in Patients with Metastatic Castration-Resistant Prostate Cancer

by Chun Wang, Zhenchao Zhang, Weelic Chong, Rui Luo, Ronald E. Myers, Jian Gu, Jianqing Lin, Qiang Wei, Bingshan Li, Timothy R. Rebbeck, Grace Lu-Yao, William K. Kelly, Hushan Yang
Published 2021-01-01

Whole-exome sequencing identifies somatic mutations and intratumor heterogeneity in inflammatory breast cancer

by Rui Luo, Weelic Chong, Qiang Wei, Zhenchao Zhang, Chun Wang, Zhong Ye, Maysa M. Abu-Khalaf, Daniel P. Silver, Robert T. Stapp, Wei Jiang, Ronald E. Myers, Bingshan Li, Massimo Cristofanilli, Hushan Yang
Published 2021-06-01

Recurrent tissue-specific mtDNA mutations are common in humans.

by David C Samuels, Chun Li, Bingshan Li, Zhuo Song, Eric Torstenson, Hayley Boyd Clay, Antonis Rokas, Tricia A Thornton-Wells, Jason H Moore, Tia M Hughes, Robert D Hoffman, Jonathan L Haines, Deborah G Murdock, Douglas P Mortlock, Scott M Williams
Published 2013-11-01

A big-data approach to understanding metabolic rate and response to obesity in laboratory mice

by June K Corrigan, Deepti Ramachandran, Yuchen He, Colin J Palmer, Michael J Jurczak, Rui Chen, Bingshan Li, Randall H Friedline, Jason K Kim, Jon J Ramsey, Louise Lantier, Owen P McGuinness, Mouse Metabolic Phenotyping Center Energy Balance Working Group, Alexander S Banks
Published 2020-05-01

Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability.

by Serena Sanna, Bingshan Li, Antonella Mulas, Carlo Sidore, Hyun M Kang, Anne U Jackson, Maria Grazia Piras, Gianluca Usala, Giuseppe Maninchedda, Alessandro Sassu, Fabrizio Serra, Maria Antonietta Palmas, William H Wood, Inger Njølstad, Markku Laakso, Kristian Hveem, Jaakko Tuomilehto, Timo A Lakka, Rainer Rauramaa, Michael Boehnke, Francesco Cucca, Manuela Uda, David Schlessinger, Ramaiah Nagaraja, Gonçalo R Abecasis
Published 2011-07-01

An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk

by Lang Wu, Yaohua Yang, Xingyi Guo, Xiao-Ou Shu, Qiuyin Cai, Xiang Shu, Bingshan Li, Ran Tao, Chong Wu, Jason B. Nikas, Yanfa Sun, Jingjing Zhu, Monique J. Roobol, Graham G. Giles, Hermann Brenner, Esther M. John, Judith Clements, Eli Marie Grindedal, Jong Y. Park, Janet L. Stanford, Zsofia Kote-Jarai, Christopher A. Haiman, Rosalind A. Eeles, Wei Zheng, Jirong Long, The PRACTICAL consortium, CRUK Consortium, BPC3 Consortium, CAPS Consortium, PEGASUS Consortium
Published 2020-08-01

A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

by Dong Li, Xiao Chang, John J. Connolly, Lifeng Tian, Yichuan Liu, Elizabeth J. Bhoj, Nora Robinson, Debra Abrams, Yun R. Li, Jonathan P. Bradfield, Cecilia E. Kim, Jin Li, Fengxiang Wang, James Snyder, Maria Lemma, Cuiping Hou, Zhi Wei, Yiran Guo, Haijun Qiu, Frank D. Mentch, Kelly A. Thomas, Rosetta M. Chiavacci, Roger Cone, Bingshan Li, Patrick A. Sleiman, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Price Foundation Collaborative Group, Hakon Hakonarson
Published 2017-06-01

Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

by Dong Li, Xiao Chang, John J. Connolly, Lifeng Tian, Yichuan Liu, Elizabeth J. Bhoj, Nora Robinson, Debra Abrams, Yun R. Li, Jonathan P. Bradfield, Cecilia E. Kim, Jin Li, Fengxiang Wang, James Snyder, Maria Lemma, Cuiping Hou, Zhi Wei, Yiran Guo, Haijun Qiu, Frank D. Mentch, Kelly A. Thomas, Rosetta M. Chiavacci, Roger Cone, Bingshan Li, Patrick A. Sleiman, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Price Foundation Collaborative Group, Hakon Hakonarson
Published 2017-08-01

Genome sequencing unveils a regulatory landscape of platelet reactivity

by Ali R. Keramati, Ming-Huei Chen, Benjamin A. T. Rodriguez, Lisa R. Yanek, Arunoday Bhan, Brady J. Gaynor, Kathleen Ryan, Jennifer A. Brody, Xue Zhong, Qiang Wei, NHLBI Trans-Omics for Precision (TOPMed) Consortium, Kai Kammers, Kanika Kanchan, Kruthika Iyer, Madeline H. Kowalski, Achilleas N. Pitsillides, L. Adrienne Cupples, Bingshan Li, Thorsten M. Schlaeger, Alan R. Shuldiner, Jeffrey R. O’Connell, Ingo Ruczinski, Braxton D. Mitchell, Nauder Faraday, Margaret A. Taub, Lewis C. Becker, Joshua P. Lewis, Rasika A. Mathias, Andrew D. Johnson
Published 2021-06-01