Towards Goals to Refine Prophylactic and Therapeutic Strategies Against COVID-19 Linked to Aging and Metabolic Syndrome

by Chong-Hyun Shin, Ki-Hye Kim, Subbiah Jeeva, Sang-Moo Kang
Published 2021-06-01

An Update on mRNA-Based Viral Vaccines

by Subbiah Jeeva, Ki-Hye Kim, Chong Hyun Shin, Bao-Zhong Wang, Sang-Moo Kang
Published 2021-08-01

Recombinant Live Attenuated Influenza Virus Expressing Conserved G-Protein Domain in a Chimeric Hemagglutinin Molecule Induces G-Specific Antibodies and Confers Protection against...

by Yu-Jin Jung, Yu-Na Lee, Ki-Hye Kim, Youri Lee, Subbiah Jeeva, Bo Ryoung Park, Sang-Moo Kang
Published 2020-12-01

Intranasal vaccination with M2e5x virus-like particles induces humoral and cellular immune responses conferring cross-protection against heterosubtypic influenza viruses.

by Young-Tae Lee, Eun-Ju Ko, Youri Lee, Ki-Hye Kim, Min-Chul Kim, Yu-Na Lee, Sang-Moo Kang
Published 2018-01-01

Roles of the Fc Receptor γ-Chain in Inducing Protective Immune Responses after Heterologous Vaccination against Respiratory Syncytial Virus Infection

by Hye Suk Hwang, Young-Tae Lee, Ki-Hye Kim, Ho Seong Seo, Kap Seung Yang, Hoonsung Cho, Sang-Moo Kang
Published 2021-03-01

Immunogenicity and Neutralizing Activity Comparison of SARS-CoV-2 Spike Full-Length and Subunit Domain Proteins in Young Adult and Old-Aged Mice

by Ki-Hye Kim, Noopur Bhatnagar, Subbiah Jeeva, Judy Oh, Bo Ryoung Park, Chong Hyun Shin, Bao-Zhong Wang, Sang-Moo Kang
Published 2021-03-01

A Strategy to Elicit M2e-Specific Antibodies Using a Recombinant H7N9 Live Attenuated Influenza Vaccine Expressing Multiple M2e Tandem Repeats

by Daria Mezhenskaya, Irina Isakova-Sivak, Tatiana Kotomina, Victoria Matyushenko, Min-Chul Kim, Noopur Bhatnagar, Ki-Hye Kim, Sang-Moo Kang, Larisa Rudenko
Published 2021-02-01

BCG Cell Wall Skeleton As a Vaccine Adjuvant Protects Both Infant and Old-Aged Mice from Influenza Virus Infection

by Ki-Hye Kim, Young-Tae Lee, Yoonsuh Park, Eun-Ju Ko, Yu-Jin Jung, Yu-Jin Kim, Eun-Kyeong Jo, Sang-Moo Kang
Published 2021-05-01

Ginseng Protects Against Respiratory Syncytial Virus by Modulating Multiple Immune Cells and Inhibiting Viral Replication

by Jong Seok Lee, Yu-Na Lee, Young-Tae Lee, Hye Suk Hwang, Ki-Hye Kim, Eun-Ju Ko, Min-Chul Kim, Sang-Moo Kang
Published 2015-02-01

Generation and Characterization of Universal Live-Attenuated Influenza Vaccine Candidates Containing Multiple M2e Epitopes

by Tatiana Kotomina, Irina Isakova-Sivak, Ki-Hye Kim, Bo Ryoung Park, Yu-Jin Jung, Youri Lee, Daria Mezhenskaya, Victoria Matyushenko, Sang-Moo Kang, Larisa Rudenko
Published 2020-11-01

Virus-Like Particles Are a Superior Platform for Presenting M2e Epitopes to Prime Humoral and Cellular Immunity against Influenza Virus

by Ki-Hye Kim, Young-Man Kwon, Young-Tae Lee, Min-Chul Kim, Hye Suk Hwang, Eun-Ju Ko, Youri Lee, Hyo-Jick Choi, Sang-Moo Kang
Published 2018-09-01

Antiviral Activity of Fermented Ginseng Extracts against a Broad Range of Influenza Viruses

by Ye Wang, Yu-Jin Jung, Ki-Hye Kim, Youngman Kwon, Yu-Jin Kim, Zhan Zhang, Heun-Soo Kang, Bao-Zhong Wang, Fu-Shi Quan, Sang-Moo Kang
Published 2018-09-01

Alum Adjuvant Enhances Protection against Respiratory Syncytial Virus but Exacerbates Pulmonary Inflammation by Modulating Multiple Innate and Adaptive Immune Cells.

by Ki-Hye Kim, Young-Tae Lee, Hye Suk Hwang, Young-Man Kwon, Yu-Jin Jung, Youri Lee, Jong Seok Lee, Yu-Na Lee, Soojin Park, Sang-Moo Kang
Published 2015-01-01

Vaccination by microneedle patch with inactivated respiratory syncytial virus and monophosphoryl lipid A enhances the protective efficacy and diminishes inflammatory disease after...

by Soojin Park, Youri Lee, Young-Man Kwon, Young-Tae Lee, Ki-Hye Kim, Eun-Ju Ko, Jae Hwan Jung, Manki Song, Barney Graham, Mark R Prausnitz, Sang-Moo Kang
Published 2018-01-01

Cross-Protective Efficacy of Influenza Virus M2e Containing Virus-Like Particles Is Superior to Hemagglutinin Vaccines and Variable Depending on the Genetic Backgrounds of Mice

by Yu-Jin Kim, Young-Tae Lee, Min-Chul Kim, Min-Chul Kim, Yu-Na Lee, Yu-Na Lee, Ki-Hye Kim, Eun-Ju Ko, Jae-Min Song, Sang-Moo Kang
Published 2017-12-01

Co-Delivery of M2e Virus-Like Particles with Influenza Split Vaccine to the Skin Using Microneedles Enhances the Efficacy of Cross Protection

by Min-Chul Kim, Ki-Hye Kim, Jeong Woo Lee, Yu-Na Lee, Hyo-Jick Choi, Yu-Jin Jung, Yu-Jin Kim, Richard W. Compans, Mark R. Prausnitz, Sang-Moo Kang
Published 2019-04-01

Broad cross protection by recombinant live attenuated influenza H3N2 seasonal virus expressing conserved M2 extracellular domain in a chimeric hemagglutinin

by Bo Ryoung Park, Ki-Hye Kim, Tatiana Kotomina, Min-Chul Kim, Young-Man Kwon, Subbiah Jeeva, Yu-Jin Jung, Noopur Bhatnagar, Irina Isakova-Sivak, Daria Mezhenskaya, Larisa Rudenko, Bao-Zhong Wang, Sang-Moo Kang
Published 2021-02-01