Dissolvable Microneedle Patches to Enable Increased Access to Vaccines against SARS-CoV-2 and Future Pandemic Outbreaks

by Jesse O’Shea, Mark R. Prausnitz, Nadine Rouphael
Published 2021-04-01

Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch

by Wandi Zhu, Song Li, Chao Wang, Guoying Yu, Mark R. Prausnitz, Bao-Zhong Wang
Published 2018-07-01

Administration of pilocarpine by microneedle patch as a novel method for cystic fibrosis sweat testing

by Song Li, Kelsey Hart, Natalie Norton, Clare A. Ryan, Lokesh Guglani, Mark R. Prausnitz
Published 2021-09-01

cGAMP/Saponin Adjuvant Combination Improves Protective Response to Influenza Vaccination by Microneedle Patch in an Aged Mouse Model

by Elena V. Vassilieva, Song Li, Heorhiy Korniychuk, Dahnide M. Taylor, Shelly Wang, Mark R. Prausnitz, Richard W. Compans
Published 2021-02-01

Effect of Osmotic Pressure on the Stability of Whole Inactivated Influenza Vaccine for Coating on Microneedles.

by Hyo-Jick Choi, Jae-Min Song, Brian J Bondy, Richard W Compans, Sang-Moo Kang, Mark R Prausnitz
Published 2015-01-01

Stabilization of influenza vaccine enhances protection by microneedle delivery in the mouse skin.

by Fu-Shi Quan, Yeu-Chun Kim, Dae-Goon Yoo, Richard W Compans, Mark R Prausnitz, Sang-Moo Kang
Published 2009-09-01

Transdermal influenza immunization with vaccine-coated microneedle arrays.

by Dimitrios G Koutsonanos, Maria del Pilar Martin, Vladimir G Zarnitsyn, Sean P Sullivan, Richard W Compans, Mark R Prausnitz, Ioanna Skountzou
Published 2009-01-01

Effect of adjuvants on responses to skin immunization by microneedles coated with influenza subunit vaccine.

by William C Weldon, Vladimir G Zarnitsyn, E Stein Esser, Misha T Taherbhai, Dimitrios G Koutsonanos, Elena V Vassilieva, Ioanna Skountzou, Mark R Prausnitz, Richard W Compans
Published 2012-01-01

Microneedle patch delivery of influenza vaccine during pregnancy enhances maternal immune responses promoting survival and long-lasting passive immunity to offspring

by E. Stein Esser, Joanna A. Pulit-Penaloza, Haripriya Kalluri, Devin McAllister, Elena V. Vassilieva, Elizabeth Q. Littauer, Nadia Lelutiu, Mark R. Prausnitz, Richard W. Compans, Ioanna Skountzou
Published 2017-07-01

Vaccination with human papillomavirus pseudovirus-encapsidated plasmids targeted to skin using microneedles.

by Rhonda C Kines, Vladimir Zarnitsyn, Teresa R Johnson, Yuk-Ying S Pang, Kizzmekia S Corbett, John D Nicewonger, Anu Gangopadhyay, Man Chen, Jie Liu, Mark R Prausnitz, John T Schiller, Barney S Graham
Published 2015-01-01

Vaccination by microneedle patch with inactivated respiratory syncytial virus and monophosphoryl lipid A enhances the protective efficacy and diminishes inflammatory disease after...

by Soojin Park, Youri Lee, Young-Man Kwon, Young-Tae Lee, Ki-Hye Kim, Eun-Ju Ko, Jae Hwan Jung, Manki Song, Barney Graham, Mark R Prausnitz, Sang-Moo Kang
Published 2018-01-01

Co-Delivery of M2e Virus-Like Particles with Influenza Split Vaccine to the Skin Using Microneedles Enhances the Efficacy of Cross Protection

by Min-Chul Kim, Ki-Hye Kim, Jeong Woo Lee, Yu-Na Lee, Hyo-Jick Choi, Yu-Jin Jung, Yu-Jin Kim, Richard W. Compans, Mark R. Prausnitz, Sang-Moo Kang
Published 2019-04-01

Immunologic mechanisms of seasonal influenza vaccination administered by microneedle patch from a randomized phase I trial

by Nadine G. Rouphael, Lilin Lai, Sonia Tandon, Michele Paine McCullough, Yunchuan Kong, Sarah Kabbani, Muktha S. Natrajan, Yongxian Xu, Yerun Zhu, Dongli Wang, Jesse O’Shea, Amy Sherman, Tianwei Yu, Sebastien Henry, Devin McAllister, Daniel Stadlbauer, Surender Khurana, Hana Golding, Florian Krammer, Mark J. Mulligan, Mark R. Prausnitz
Published 2021-07-01